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PubMed code 319234

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydrofolate reductase


(Escherichia coli)
BDBM50391226
PNG
(CHEMBL265493)
Show SMILES Nc1ncc(Cc2ccccc2)c(N)n1
Show InChI InChI=1S/C11H12N4/c12-10-9(7-14-11(13)15-10)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H4,12,13,14,15)
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Similars

Article
PubMed
n/an/a 3.39E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli dihydrofolate reductase


J Med Chem 20: 96-102 (1977)


Article DOI: 10.1021/jm00211a020
BindingDB Entry DOI: 10.7270/Q2348PC5
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%