Affinity Data by PubMed id=3612682

PubMed code 3612682

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dopamine beta-hydroxylase (Rattus norvegicus)	BDBM50000439 (5-Butyl-pyridine-2-carboxylic acid \| 5-Butyl-pyrid...) Show SMILES CCCCc1ccc(nc1)C(O)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 0.4-1.1				J Med Chem 30: 1309-13 (1987) BindingDB Entry DOI: 10.7270/Q2MC8Z0M
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Rattus norvegicus)	BDBM50014983 (1-(3,5-Difluoro-benzyl)-1,3-dihydro-imidazole-2-th...) Show SMILES Fc1cc(F)cc(Cn2cc[nH]c2=S)c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 1.1-1.4				J Med Chem 30: 1309-13 (1987) BindingDB Entry DOI: 10.7270/Q2MC8Z0M
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Rattus norvegicus)	BDBM50014968 (1-(4-Hydroxy-benzyl)-1,3-dihydro-imidazole-2-thion...) Show SMILES Oc1ccc(Cn2cc[nH]c2=S)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 1.3-4.6				J Med Chem 30: 1309-13 (1987) BindingDB Entry DOI: 10.7270/Q2MC8Z0M
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Rattus norvegicus)	BDBM50014960 (1-Benzyl-1,3-dihydro-imidazole-2-thione \| 1-Benzyl...) Show SMILES S=c1[nH]ccn1Cc1ccccc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value range from 8.9-13				J Med Chem 30: 1309-13 (1987) BindingDB Entry DOI: 10.7270/Q2MC8Z0M
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Rattus norvegicus)	BDBM50024476 (1-(5-Hydroxy-pyridin-2-ylmethyl)-1,3-dihydro-imida...) Show SMILES Oc1ccc(Cn2cc[nH]c2=S)nc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 21-35				J Med Chem 30: 1309-13 (1987) BindingDB Entry DOI: 10.7270/Q2MC8Z0M
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Rattus norvegicus)	BDBM50024478 (1-Pyridin-3-ylmethyl-1,3-dihydro-imidazole-2-thion...) Show SMILES S=c1[nH]ccn1Cc1cccnc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.04E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 89-121				J Med Chem 30: 1309-13 (1987) BindingDB Entry DOI: 10.7270/Q2MC8Z0M
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Rattus norvegicus)	BDBM50024477 (1-Pyridin-2-ylmethyl-1,3-dihydro-imidazole-2-thion...) Show SMILES S=c1[nH]ccn1Cc1ccccn1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 76-220				J Med Chem 30: 1309-13 (1987) BindingDB Entry DOI: 10.7270/Q2MC8Z0M
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%