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Articleid 50029396

Compile data set for download or QSAR
Found 25 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50041961
PNG
(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C
Show InChI InChI=1S/C18H29NO/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4/h7-9,14,17H,5-6,10-13H2,1-4H3/t14-,17+/m0/s1
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Article
 4.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50041961
PNG
(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C
Show InChI InChI=1S/C18H29NO/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4/h7-9,14,17H,5-6,10-13H2,1-4H3/t14-,17+/m0/s1
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 15n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]-U-86,170)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50041959
PNG
(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C
Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1
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 26n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50284086
PNG
(CHEMBL161811 | Trifluoro-methanesulfonic acid (5S,...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C
Show InChI InChI=1S/C18H26F3NO3S/c1-4-11-22(12-5-2)16-10-9-15-14(13(16)3)7-6-8-17(15)25-26(23,24)18(19,20)21/h6-8,13,16H,4-5,9-12H2,1-3H3/t13-,16+/m0/s1
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 40n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens (Human))		BDBM50041961
PNG
(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C
Show InChI InChI=1S/C18H29NO/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4/h7-9,14,17H,5-6,10-13H2,1-4H3/t14-,17+/m0/s1
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 48n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens (Human))		BDBM50041959
PNG
(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C
Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1
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 117n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens (Human))		BDBM50284086
PNG
(CHEMBL161811 | Trifluoro-methanesulfonic acid (5S,...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C
Show InChI InChI=1S/C18H26F3NO3S/c1-4-11-22(12-5-2)16-10-9-15-14(13(16)3)7-6-8-17(15)25-26(23,24)18(19,20)21/h6-8,13,16H,4-5,9-12H2,1-3H3/t13-,16+/m0/s1
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 121n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50041959
PNG
(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C
Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1
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 145n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]-U-86,170)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 5A


(Homo sapiens (Human))		BDBM50041961
PNG
(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C
Show InChI InChI=1S/C18H29NO/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4/h7-9,14,17H,5-6,10-13H2,1-4H3/t14-,17+/m0/s1
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 168n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]-8-OH-DPAT )

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50284083
PNG
(CHEMBL349843 | Trifluoro-methanesulfonic acid (5S,...)
Show SMILES CCCN[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C
Show InChI InChI=1S/C15H20F3NO3S/c1-3-9-19-13-8-7-12-11(10(13)2)5-4-6-14(12)22-23(20,21)15(16,17)18/h4-6,10,13,19H,3,7-9H2,1-2H3/t10-,13+/m0/s1
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 171n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50284084
PNG
((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Show SMILES CCCN[C@@H]1CCc2c(cccc2C(=O)OC)[C@@H]1C
Show InChI InChI=1S/C16H23NO2/c1-4-10-17-15-9-8-13-12(11(15)2)6-5-7-14(13)16(18)19-3/h5-7,11,15,17H,4,8-10H2,1-3H3/t11-,15+/m0/s1
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 253n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 5A


(Homo sapiens (Human))		BDBM50284084
PNG
((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Show SMILES CCCN[C@@H]1CCc2c(cccc2C(=O)OC)[C@@H]1C
Show InChI InChI=1S/C16H23NO2/c1-4-10-17-15-9-8-13-12(11(15)2)6-5-7-14(13)16(18)19-3/h5-7,11,15,17H,4,8-10H2,1-3H3/t11-,15+/m0/s1
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 287n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]-8-OH-DPAT )

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50284086
PNG
(CHEMBL161811 | Trifluoro-methanesulfonic acid (5S,...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C
Show InChI InChI=1S/C18H26F3NO3S/c1-4-11-22(12-5-2)16-10-9-15-14(13(16)3)7-6-8-17(15)25-26(23,24)18(19,20)21/h6-8,13,16H,4-5,9-12H2,1-3H3/t13-,16+/m0/s1
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 546n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]-U-86,170)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens (Human))		BDBM50284083
PNG
(CHEMBL349843 | Trifluoro-methanesulfonic acid (5S,...)
Show SMILES CCCN[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C
Show InChI InChI=1S/C15H20F3NO3S/c1-3-9-19-13-8-7-12-11(10(13)2)5-4-6-14(12)22-23(20,21)15(16,17)18/h4-6,10,13,19H,3,7-9H2,1-2H3/t10-,13+/m0/s1
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 621n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(4) dopamine receptor


(Homo sapiens (Human))		BDBM50284084
PNG
((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Show SMILES CCCN[C@@H]1CCc2c(cccc2C(=O)OC)[C@@H]1C
Show InChI InChI=1S/C16H23NO2/c1-4-10-17-15-9-8-13-12(11(15)2)6-5-7-14(13)16(18)19-3/h5-7,11,15,17H,4,8-10H2,1-3H3/t11-,15+/m0/s1
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 1.59E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50284082
PNG
((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Show SMILES CCCN[C@@H]1CCc2c(cccc2[C@@H]1C)C#N
Show InChI InChI=1S/C15H20N2/c1-3-9-17-15-8-7-14-12(10-16)5-4-6-13(14)11(15)2/h4-6,11,15,17H,3,7-9H2,1-2H3/t11-,15+/m0/s1
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>1.79E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]-8-OH-DPAT )

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50284084
PNG
((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Show SMILES CCCN[C@@H]1CCc2c(cccc2C(=O)OC)[C@@H]1C
Show InChI InChI=1S/C16H23NO2/c1-4-10-17-15-9-8-13-12(11(15)2)6-5-7-14(13)16(18)19-3/h5-7,11,15,17H,4,8-10H2,1-3H3/t11-,15+/m0/s1
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 2.33E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]-U-86,170)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 5A


(Homo sapiens (Human))		BDBM50041959
PNG
(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Show SMILES CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C
Show InChI InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1
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 2.33E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]-8-OH-DPAT )

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50284083
PNG
(CHEMBL349843 | Trifluoro-methanesulfonic acid (5S,...)
Show SMILES CCCN[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C
Show InChI InChI=1S/C15H20F3NO3S/c1-3-9-19-13-8-7-12-11(10(13)2)5-4-6-14(12)22-23(20,21)15(16,17)18/h4-6,10,13,19H,3,7-9H2,1-2H3/t10-,13+/m0/s1
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Article
 2.56E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]-U-86,170)

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 5A


(Homo sapiens (Human))		BDBM50284083
PNG
(CHEMBL349843 | Trifluoro-methanesulfonic acid (5S,...)
Show SMILES CCCN[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C
Show InChI InChI=1S/C15H20F3NO3S/c1-3-9-19-13-8-7-12-11(10(13)2)5-4-6-14(12)22-23(20,21)15(16,17)18/h4-6,10,13,19H,3,7-9H2,1-2H3/t10-,13+/m0/s1
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 3.07E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]-8-OH-DPAT )

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 5A


(Homo sapiens (Human))		BDBM50284086
PNG
(CHEMBL161811 | Trifluoro-methanesulfonic acid (5S,...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2[C@@H]1C
Show InChI InChI=1S/C18H26F3NO3S/c1-4-11-22(12-5-2)16-10-9-15-14(13(16)3)7-6-8-17(15)25-26(23,24)18(19,20)21/h6-8,13,16H,4-5,9-12H2,1-3H3/t13-,16+/m0/s1
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>3.45E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]-8-OH-DPAT )

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50284085
PNG
((5S,6R)-6-Dipropylamino-5-methyl-5,6,7,8-tetrahydr...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(cccc2[C@@H]1C)C#N
Show InChI InChI=1S/C18H26N2/c1-4-11-20(12-5-2)18-10-9-17-15(13-19)7-6-8-16(17)14(18)3/h6-8,14,18H,4-5,9-12H2,1-3H3/t14-,18+/m0/s1
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 5.04E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at 5-HT1A receptor in rat striatal membranes using [3H]-8-OH-DPAT

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50284085
PNG
((5S,6R)-6-Dipropylamino-5-methyl-5,6,7,8-tetrahydr...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(cccc2[C@@H]1C)C#N
Show InChI InChI=1S/C18H26N2/c1-4-11-20(12-5-2)18-10-9-17-15(13-19)7-6-8-16(17)14(18)3/h6-8,14,18H,4-5,9-12H2,1-3H3/t14-,18+/m0/s1
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 6.67E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured from rat striatal membrane using [3H]-spiperone at D2 receptors

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50284087
PNG
((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Show SMILES CCCN[C@@H]1CCc2c(cccc2C(N)=O)[C@@H]1C
Show InChI InChI=1S/C15H22N2O/c1-3-9-17-14-8-7-12-11(10(14)2)5-4-6-13(12)15(16)18/h4-6,10,14,17H,3,7-9H2,1-2H3,(H2,16,18)/t10-,14+/m0/s1
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 6.72E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured at 5-HT1A receptor in rat striatal membranes using [3H]-8-OH-DPAT

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50284082
PNG
((5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-...)
Show SMILES CCCN[C@@H]1CCc2c(cccc2[C@@H]1C)C#N
Show InChI InChI=1S/C15H20N2/c1-3-9-17-15-8-7-14-12(10-16)5-4-6-13(14)11(15)2/h4-6,11,15,17H,3,7-9H2,1-2H3/t11-,15+/m0/s1
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 1.67E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound was measured from rat striatal membrane using [3H]-spiperone at D2 receptors

Bioorg Med Chem Lett 4: 689-694 (1994)


Article DOI: 10.1016/S0960-894X(01)80181-5
BindingDB Entry DOI: 10.7270/Q2SX6D5J
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%