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Articleid 50029596

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Substance-K receptor


(HAMSTER)		BDBM50285956
PNG
(4-(4-Chloro-phenylamino)-6-isopropyl-2-morpholin-4...)
Show SMILES CC(C)N1Cc2c(nc(nc2Nc2ccc(Cl)cc2)N2CCOCC2)C1=O
Show InChI InChI=1S/C19H22ClN5O2/c1-12(2)25-11-15-16(18(25)26)22-19(24-7-9-27-10-8-24)23-17(15)21-14-5-3-13(20)4-6-14/h3-6,12H,7-11H2,1-2H3,(H,21,22,23)
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 15n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285956
PNG
(4-(4-Chloro-phenylamino)-6-isopropyl-2-morpholin-4...)
Show SMILES CC(C)N1Cc2c(nc(nc2Nc2ccc(Cl)cc2)N2CCOCC2)C1=O
Show InChI InChI=1S/C19H22ClN5O2/c1-12(2)25-11-15-16(18(25)26)22-19(24-7-9-27-10-8-24)23-17(15)21-14-5-3-13(20)4-6-14/h3-6,12H,7-11H2,1-2H3,(H,21,22,23)
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 15n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(HAMSTER)		BDBM50285943
PNG
((4-Chloro-phenyl)-(2-morpholin-4-yl-8-propyl-9H-pu...)
Show SMILES CCCc1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCOCC1
Show InChI InChI=1S/C18H21ClN6O/c1-2-3-14-21-15-16(20-13-6-4-12(19)5-7-13)23-18(24-17(15)22-14)25-8-10-26-11-9-25/h4-7H,2-3,8-11H2,1H3,(H2,20,21,22,23,24)
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 54n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285955
PNG
((4-Chloro-phenyl)-(8-isopropyl-2-morpholin-4-yl-9H...)
Show SMILES CC(C)c1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCOCC1
Show InChI InChI=1S/C18H21ClN6O/c1-11(2)15-21-14-16(20-13-5-3-12(19)4-6-13)23-18(24-17(14)22-15)25-7-9-26-10-8-25/h3-6,11H,7-10H2,1-2H3,(H2,20,21,22,23,24)
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 67n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(HAMSTER)		BDBM50285955
PNG
((4-Chloro-phenyl)-(8-isopropyl-2-morpholin-4-yl-9H...)
Show SMILES CC(C)c1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCOCC1
Show InChI InChI=1S/C18H21ClN6O/c1-11(2)15-21-14-16(20-13-5-3-12(19)4-6-13)23-18(24-17(14)22-15)25-7-9-26-10-8-25/h3-6,11H,7-10H2,1-2H3,(H2,20,21,22,23,24)
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 67n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285944
PNG
((4-Chloro-phenyl)-(8-ethyl-2-morpholin-4-yl-9H-pur...)
Show SMILES CCc1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCOCC1
Show InChI InChI=1S/C17H19ClN6O/c1-2-13-20-14-15(19-12-5-3-11(18)4-6-12)22-17(23-16(14)21-13)24-7-9-25-10-8-24/h3-6H,2,7-10H2,1H3,(H2,19,20,21,22,23)
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 520n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(HAMSTER)		BDBM50285944
PNG
((4-Chloro-phenyl)-(8-ethyl-2-morpholin-4-yl-9H-pur...)
Show SMILES CCc1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCOCC1
Show InChI InChI=1S/C17H19ClN6O/c1-2-13-20-14-15(19-12-5-3-11(18)4-6-12)22-17(23-16(14)21-13)24-7-9-25-10-8-24/h3-6H,2,7-10H2,1H3,(H2,19,20,21,22,23)
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 520n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(HAMSTER)		BDBM50285950
PNG
(4-(4-Chloro-phenylamino)-2-morpholin-4-yl-quinazol...)
Show SMILES COC(=O)c1ccc2c(Nc3ccc(Cl)cc3)nc(nc2c1)N1CCOCC1
Show InChI InChI=1S/C20H19ClN4O3/c1-27-19(26)13-2-7-16-17(12-13)23-20(25-8-10-28-11-9-25)24-18(16)22-15-5-3-14(21)4-6-15/h2-7,12H,8-11H2,1H3,(H,22,23,24)
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 820n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285957
PNG
(1-[8-Isopropyl-6-(4-trifluoromethyl-phenylamino)-9...)
Show SMILES CC(C)c1nc2nc(nc(Nc3ccc(cc3)C(F)(F)F)c2[nH]1)N1CCC(O)CC1
Show InChI InChI=1S/C20H23F3N6O/c1-11(2)16-25-15-17(24-13-5-3-12(4-6-13)20(21,22)23)27-19(28-18(15)26-16)29-9-7-14(30)8-10-29/h3-6,11,14,30H,7-10H2,1-2H3,(H2,24,25,26,27,28)
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 1.77E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-NKA from the cloned human Tachykinin receptor 2 which has been expressed in baculovirus infected insect sf21 cells

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285959
PNG
(1-[6-(4-Chloro-phenylamino)-8-isopropyl-9H-purin-2...)
Show SMILES CC(C)c1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCC(C)(O)CC1
Show InChI InChI=1S/C20H25ClN6O/c1-12(2)16-23-15-17(22-14-6-4-13(21)5-7-14)25-19(26-18(15)24-16)27-10-8-20(3,28)9-11-27/h4-7,12,28H,8-11H2,1-3H3,(H2,22,23,24,25,26)
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 2.10E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-NKA from the cloned human Tachykinin receptor 2 which has been expressed in baculovirus infected insect sf21 cells

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285945
PNG
(1-[6-(4-Chloro-phenylamino)-8-isopropyl-9H-purin-2...)
Show SMILES CC(C)c1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCC(O)(CC1)c1ccccc1
Show InChI InChI=1S/C25H27ClN6O/c1-16(2)21-28-20-22(27-19-10-8-18(26)9-11-19)30-24(31-23(20)29-21)32-14-12-25(33,13-15-32)17-6-4-3-5-7-17/h3-11,16,33H,12-15H2,1-2H3,(H2,27,28,29,30,31)
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 2.24E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-NKA from the cloned human Tachykinin receptor 2 which has been expressed in baculovirus infected insect sf21 cells

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285943
PNG
((4-Chloro-phenyl)-(2-morpholin-4-yl-8-propyl-9H-pu...)
Show SMILES CCCc1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCOCC1
Show InChI InChI=1S/C18H21ClN6O/c1-2-3-14-21-15-16(20-13-6-4-12(19)5-7-13)23-18(24-17(15)22-14)25-8-10-26-11-9-25/h4-7H,2-3,8-11H2,1H3,(H2,20,21,22,23,24)
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 2.34E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from the cloned human NK2 receptor

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285952
PNG
(CHEMBL321137 | N*2*-(3-Amino-propyl)-N*6*-(4-chlor...)
Show SMILES CC(C)c1nc2nc(NCCCN)nc(Nc3ccc(Cl)cc3)c2[nH]1
Show InChI InChI=1S/C17H22ClN7/c1-10(2)14-22-13-15(21-12-6-4-11(18)5-7-12)24-17(20-9-3-8-19)25-16(13)23-14/h4-7,10H,3,8-9,19H2,1-2H3,(H3,20,21,22,23,24,25)
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 2.55E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-NKA from the cloned human Tachykinin receptor 2 which has been expressed in baculovirus infected insect sf21 cells

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285948
PNG
((8-Isopropyl-2-morpholin-4-yl-9H-purin-6-yl)-(4-tr...)
Show SMILES CC(C)c1nc2nc(nc(Nc3ccc(cc3)C(F)(F)F)c2[nH]1)N1CCOCC1
Show InChI InChI=1S/C19H21F3N6O/c1-11(2)15-24-14-16(23-13-5-3-12(4-6-13)19(20,21)22)26-18(27-17(14)25-15)28-7-9-29-10-8-28/h3-6,11H,7-10H2,1-2H3,(H2,23,24,25,26,27)
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 2.85E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-NKA from the cloned human Tachykinin receptor 2 which has been expressed in baculovirus infected insect sf21 cells

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285946
PNG
((4-Chloro-phenyl)-[2-(4,4-dimethoxy-piperidin-1-yl...)
Show SMILES COC1(CCN(CC1)c1nc(Nc2ccc(Cl)cc2)c2[nH]c(nc2n1)C(C)C)OC
Show InChI InChI=1S/C21H27ClN6O2/c1-13(2)17-24-16-18(23-15-7-5-14(22)6-8-15)26-20(27-19(16)25-17)28-11-9-21(29-3,30-4)10-12-28/h5-8,13H,9-12H2,1-4H3,(H2,23,24,25,26,27)
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 3.44E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-NKA from the cloned human Tachykinin receptor 2 which has been expressed in baculovirus infected insect sf21 cells

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285949
PNG
(CHEMBL97140 | N*6*-(4-Chloro-phenyl)-8-isopropyl-N...)
Show SMILES CCCNc1nc(Nc2ccc(Cl)cc2)c2[nH]c(nc2n1)C(C)C
Show InChI InChI=1S/C17H21ClN6/c1-4-9-19-17-23-15(20-12-7-5-11(18)6-8-12)13-16(24-17)22-14(21-13)10(2)3/h5-8,10H,4,9H2,1-3H3,(H3,19,20,21,22,23,24)
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 3.49E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-NKA from the cloned human Tachykinin receptor 2 which has been expressed in baculovirus infected insect sf21 cells

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285958
PNG
((4-Chloro-phenyl)-[2-(1,4-dioxa-8-aza-spiro[4.5]de...)
Show SMILES CC(C)c1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCC2(CC1)OCCO2
Show InChI InChI=1S/C21H25ClN6O2/c1-13(2)17-24-16-18(23-15-5-3-14(22)4-6-15)26-20(27-19(16)25-17)28-9-7-21(8-10-28)29-11-12-30-21/h3-6,13H,7-12H2,1-2H3,(H2,23,24,25,26,27)
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 4.36E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-NKA from the cloned human Tachykinin receptor 2 which has been expressed in baculovirus infected insect sf21 cells

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285961
PNG
(CHEMBL318880 | N*2*-Benzyl-N*6*-(4-chloro-phenyl)-...)
Show SMILES CC(C)c1nc2nc(NCc3ccccc3)nc(Nc3ccc(Cl)cc3)c2[nH]1
Show InChI InChI=1S/C21H21ClN6/c1-13(2)18-25-17-19(24-16-10-8-15(22)9-11-16)27-21(28-20(17)26-18)23-12-14-6-4-3-5-7-14/h3-11,13H,12H2,1-2H3,(H3,23,24,25,26,27,28)
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 5.58E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-NKA from the cloned human Tachykinin receptor 2 which has been expressed in baculovirus infected insect sf21 cells

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285951
PNG
(1-[6-(4-Chloro-phenylamino)-8-isopropyl-9H-purin-2...)
Show SMILES CC(C)c1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCC(=O)CC1
Show InChI InChI=1S/C19H21ClN6O/c1-11(2)16-22-15-17(21-13-5-3-12(20)4-6-13)24-19(25-18(15)23-16)26-9-7-14(27)8-10-26/h3-6,11H,7-10H2,1-2H3,(H2,21,22,23,24,25)
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 5.89E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-NKA from the cloned human Tachykinin receptor 2 which has been expressed in baculovirus infected insect sf21 cells

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(Homo sapiens (Human))		BDBM50285954
PNG
((4-Chloro-phenyl)-(8-methyl-2-morpholin-4-yl-9H-pu...)
Show SMILES Cc1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCOCC1
Show InChI InChI=1S/C16H17ClN6O/c1-10-18-13-14(19-10)21-16(23-6-8-24-9-7-23)22-15(13)20-12-4-2-11(17)3-5-12/h2-5H,6-9H2,1H3,(H2,18,19,20,21,22)
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 6.60E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(HAMSTER)		BDBM50285954
PNG
((4-Chloro-phenyl)-(8-methyl-2-morpholin-4-yl-9H-pu...)
Show SMILES Cc1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCOCC1
Show InChI InChI=1S/C16H17ClN6O/c1-10-18-13-14(19-10)21-16(23-6-8-24-9-7-23)22-15(13)20-12-4-2-11(17)3-5-12/h2-5H,6-9H2,1H3,(H2,18,19,20,21,22)
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 6.60E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(HAMSTER)		BDBM50285947
PNG
(4-(4-Chloro-phenylamino)-2-morpholin-4-yl-quinazol...)
Show SMILES OC(=O)c1ccc2c(Nc3ccc(Cl)cc3)nc(nc2c1)N1CCOCC1
Show InChI InChI=1S/C19H17ClN4O3/c20-13-2-4-14(5-3-13)21-17-15-6-1-12(18(25)26)11-16(15)22-19(23-17)24-7-9-27-10-8-24/h1-6,11H,7-10H2,(H,25,26)(H,21,22,23)
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 2.03E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(HAMSTER)		BDBM50285953
PNG
((4-Chloro-phenyl)-(2-morpholin-4-yl-quinazolin-4-y...)
Show SMILES Clc1ccc(Nc2nc(nc3ccccc23)N2CCOCC2)cc1
Show InChI InChI=1S/C18H17ClN4O/c19-13-5-7-14(8-6-13)20-17-15-3-1-2-4-16(15)21-18(22-17)23-9-11-24-12-10-23/h1-8H,9-12H2,(H,20,21,22)
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 2.95E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
Substance-K receptor


(HAMSTER)		BDBM50285960
PNG
(4-(4-Chloro-phenylamino)-2-morpholin-4-yl-quinazol...)
Show SMILES CC(C)NC(=O)c1ccc2c(Nc3ccc(Cl)cc3)nc(nc2c1)N1CCOCC1
Show InChI InChI=1S/C22H24ClN5O2/c1-14(2)24-21(29)15-3-8-18-19(13-15)26-22(28-9-11-30-12-10-28)27-20(18)25-17-6-4-16(23)5-7-17/h3-8,13-14H,9-12H2,1-2H3,(H,24,29)(H,25,26,27)
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 5.87E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)

Bioorg Med Chem Lett 5: 2879-2884 (1995)


Article DOI: 10.1016/0960-894X(95)00502-K
BindingDB Entry DOI: 10.7270/Q2DV1JTQ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%