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Articleid 50029606

Compile data set for download or QSAR
Found 58 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286092
PNG
(3-(1-Methyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(cc12)C(N)=O |c:4|
Show InChI InChI=1S/C15H17N3O/c1-18-6-2-3-11(9-18)13-8-17-14-5-4-10(15(16)19)7-12(13)14/h3-5,7-8,17H,2,6,9H2,1H3,(H2,16,19)
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 3.80n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286098
PNG
(3-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccc(cc12)C(N)=O |c:6|
Show InChI InChI=1S/C17H21N3O/c1-2-7-20-8-3-4-13(11-20)15-10-19-16-6-5-12(17(18)21)9-14(15)16/h4-6,9-10,19H,2-3,7-8,11H2,1H3,(H2,18,21)
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 4.70n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286073
PNG
(5-Methoxy-3-(1,2,5,6-tetrahydro-pyridin-3-yl)-1H-i...)
Show SMILES COc1ccc2[nH]cc(C3=CCCNC3)c2c1 |t:9|
Show InChI InChI=1S/C14H16N2O/c1-17-11-4-5-14-12(7-11)13(9-16-14)10-3-2-6-15-8-10/h3-5,7,9,15-16H,2,6,8H2,1H3
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 5.70n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM81498
PNG
(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)
Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:9|
Show InChI InChI=1S/C14H16N2O/c1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10/h2-4,8-9,15-16H,5-7H2,1H3
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 11n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286089
PNG
(CHEMBL100814 | N-[3-(1-Methyl-1,2,5,6-tetrahydro-p...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(NC(C)=O)cc12 |c:4|
Show InChI InChI=1S/C16H19N3O/c1-11(20)18-13-5-6-16-14(8-13)15(9-17-16)12-4-3-7-19(2)10-12/h4-6,8-9,17H,3,7,10H2,1-2H3,(H,18,20)
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 16n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286075
PNG
(5-Bromo-3-(1-ethyl-1,2,5,6-tetrahydro-pyridin-3-yl...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccc(Br)cc12 |c:5|
Show InChI InChI=1S/C15H17BrN2/c1-2-18-7-3-4-11(10-18)14-9-17-15-6-5-12(16)8-13(14)15/h4-6,8-9,17H,2-3,7,10H2,1H3
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 24n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286095
PNG
(3-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-5-meth...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccc(C)cc12 |c:5|
Show InChI InChI=1S/C16H20N2/c1-3-18-8-4-5-13(11-18)15-10-17-16-7-6-12(2)9-14(15)16/h5-7,9-10,17H,3-4,8,11H2,1-2H3
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 42n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286076
PNG
(5-Fluoro-3-(1-methyl-1,2,5,6-tetrahydro-pyridin-3-...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(F)cc12 |c:4|
Show InChI InChI=1S/C14H15FN2/c1-17-6-2-3-10(9-17)13-8-16-14-5-4-11(15)7-12(13)14/h3-5,7-8,16H,2,6,9H2,1H3
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 43n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286084
PNG
(5-Chloro-3-(1-ethyl-1,2,5,6-tetrahydro-pyridin-3-y...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccc(Cl)cc12 |c:5|
Show InChI InChI=1S/C15H17ClN2/c1-2-18-7-3-4-11(10-18)14-9-17-15-6-5-12(16)8-13(14)15/h4-6,8-9,17H,2-3,7,10H2,1H3
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 47n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286082
PNG
(5-Bromo-3-(1-methyl-1,2,5,6-tetrahydro-pyridin-3-y...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(Br)cc12 |c:4|
Show InChI InChI=1S/C14H15BrN2/c1-17-6-2-3-10(9-17)13-8-16-14-5-4-11(15)7-12(13)14/h3-5,7-8,16H,2,6,9H2,1H3
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 50n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286097
PNG
(3-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-5-fluo...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccc(F)cc12 |c:5|
Show InChI InChI=1S/C15H17FN2/c1-2-18-7-3-4-11(10-18)14-9-17-15-6-5-12(16)8-13(14)15/h4-6,8-9,17H,2-3,7,10H2,1H3
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 67n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286100
PNG
(3-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-5-meth...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccc(OC)cc12 |c:5|
Show InChI InChI=1S/C16H20N2O/c1-3-18-8-4-5-12(11-18)15-10-17-16-7-6-13(19-2)9-14(15)16/h5-7,9-10,17H,3-4,8,11H2,1-2H3
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 71n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286074
PNG
(5-Methyl-3-(1-methyl-1,2,5,6-tetrahydro-pyridin-3-...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(C)cc12 |c:4|
Show InChI InChI=1S/C15H18N2/c1-11-5-6-15-13(8-11)14(9-16-15)12-4-3-7-17(2)10-12/h4-6,8-9,16H,3,7,10H2,1-2H3
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 72n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286099
PNG
(5-Methoxy-3-(1-methyl-1,2,5,6-tetrahydro-pyridin-3...)
Show SMILES COc1ccc2[nH]cc(C3=CCCN(C)C3)c2c1 |t:9|
Show InChI InChI=1S/C15H18N2O/c1-17-7-3-4-11(10-17)14-9-16-15-6-5-12(18-2)8-13(14)15/h4-6,8-9,16H,3,7,10H2,1-2H3
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 79n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286082
PNG
(5-Bromo-3-(1-methyl-1,2,5,6-tetrahydro-pyridin-3-y...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(Br)cc12 |c:4|
Show InChI InChI=1S/C14H15BrN2/c1-17-6-2-3-10(9-17)13-8-16-14-5-4-11(15)7-12(13)14/h3-5,7-8,16H,2,6,9H2,1H3
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 82n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286094
PNG
(1-[3-(1-Methyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(cc12)C(C)=O |c:4|
Show InChI InChI=1S/C16H18N2O/c1-11(19)12-5-6-16-14(8-12)15(9-17-16)13-4-3-7-18(2)10-13/h4-6,8-9,17H,3,7,10H2,1-2H3
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 91n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286083
PNG
(3-(1-Methyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES COC(=O)c1ccc2[nH]cc(C3=CCCN(C)C3)c2c1 |t:11|
Show InChI InChI=1S/C16H18N2O2/c1-18-7-3-4-12(10-18)14-9-17-15-6-5-11(8-13(14)15)16(19)20-2/h4-6,8-9,17H,3,7,10H2,1-2H3
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 102n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286091
PNG
(5-Chloro-3-(1-methyl-1,2,5,6-tetrahydro-pyridin-3-...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(Cl)cc12 |c:4|
Show InChI InChI=1S/C14H15ClN2/c1-17-6-2-3-10(9-17)13-8-16-14-5-4-11(15)7-12(13)14/h3-5,7-8,16H,2,6,9H2,1H3
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 107n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286091
PNG
(5-Chloro-3-(1-methyl-1,2,5,6-tetrahydro-pyridin-3-...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(Cl)cc12 |c:4|
Show InChI InChI=1S/C14H15ClN2/c1-17-6-2-3-10(9-17)13-8-16-14-5-4-11(15)7-12(13)14/h3-5,7-8,16H,2,6,9H2,1H3
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 113n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286076
PNG
(5-Fluoro-3-(1-methyl-1,2,5,6-tetrahydro-pyridin-3-...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(F)cc12 |c:4|
Show InChI InChI=1S/C14H15FN2/c1-17-6-2-3-10(9-17)13-8-16-14-5-4-11(15)7-12(13)14/h3-5,7-8,16H,2,6,9H2,1H3
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 124n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286075
PNG
(5-Bromo-3-(1-ethyl-1,2,5,6-tetrahydro-pyridin-3-yl...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccc(Br)cc12 |c:5|
Show InChI InChI=1S/C15H17BrN2/c1-2-18-7-3-4-11(10-18)14-9-17-15-6-5-12(16)8-13(14)15/h4-6,8-9,17H,2-3,7,10H2,1H3
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 125n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286093
PNG
(3-(1-Methyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(cc12)C#N |c:4|
Show InChI InChI=1S/C15H15N3/c1-18-6-2-3-12(10-18)14-9-17-15-5-4-11(8-16)7-13(14)15/h3-5,7,9,17H,2,6,10H2,1H3
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 129n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286087
PNG
(5-Bromo-3-(1-propyl-1,2,5,6-tetrahydro-pyridin-3-y...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccc(Br)cc12 |c:6|
Show InChI InChI=1S/C16H19BrN2/c1-2-7-19-8-3-4-12(11-19)15-10-18-16-6-5-13(17)9-14(15)16/h4-6,9-10,18H,2-3,7-8,11H2,1H3
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 139n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286096
PNG
(3-(1-Methyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccccc12 |c:4|
Show InChI InChI=1S/C14H16N2/c1-16-8-4-5-11(10-16)13-9-15-14-7-3-2-6-12(13)14/h2-3,5-7,9,15H,4,8,10H2,1H3
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 139n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286097
PNG
(3-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-5-fluo...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccc(F)cc12 |c:5|
Show InChI InChI=1S/C15H17FN2/c1-2-18-7-3-4-11(10-18)14-9-17-15-6-5-12(16)8-13(14)15/h4-6,8-9,17H,2-3,7,10H2,1H3
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 142n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286077
PNG
(3-(1-Methyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(O)cc12 |c:4|
Show InChI InChI=1S/C14H16N2O/c1-16-6-2-3-10(9-16)13-8-15-14-5-4-11(17)7-12(13)14/h3-5,7-8,15,17H,2,6,9H2,1H3
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 145n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286090
PNG
(3-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccccc12 |c:6|
Show InChI InChI=1S/C16H20N2/c1-2-9-18-10-5-6-13(12-18)15-11-17-16-8-4-3-7-14(15)16/h3-4,6-8,11,17H,2,5,9-10,12H2,1H3
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 146n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286084
PNG
(5-Chloro-3-(1-ethyl-1,2,5,6-tetrahydro-pyridin-3-y...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccc(Cl)cc12 |c:5|
Show InChI InChI=1S/C15H17ClN2/c1-2-18-7-3-4-11(10-18)14-9-17-15-6-5-12(16)8-13(14)15/h4-6,8-9,17H,2-3,7,10H2,1H3
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 150n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286078
PNG
(3-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-ind...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccccc12 |c:5|
Show InChI InChI=1S/C15H18N2/c1-2-17-9-5-6-12(11-17)14-10-16-15-8-4-3-7-13(14)15/h3-4,6-8,10,16H,2,5,9,11H2,1H3
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 165n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286088
PNG
(3-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-ind...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccc(cc12)C#N |c:5|
Show InChI InChI=1S/C16H17N3/c1-2-19-7-3-4-13(11-19)15-10-18-16-6-5-12(9-17)8-14(15)16/h4-6,8,10,18H,2-3,7,11H2,1H3
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 186n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286087
PNG
(5-Bromo-3-(1-propyl-1,2,5,6-tetrahydro-pyridin-3-y...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccc(Br)cc12 |c:6|
Show InChI InChI=1S/C16H19BrN2/c1-2-7-19-8-3-4-12(11-19)15-10-18-16-6-5-13(17)9-14(15)16/h4-6,9-10,18H,2-3,7-8,11H2,1H3
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 192n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286074
PNG
(5-Methyl-3-(1-methyl-1,2,5,6-tetrahydro-pyridin-3-...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(C)cc12 |c:4|
Show InChI InChI=1S/C15H18N2/c1-11-5-6-15-13(8-11)14(9-16-15)12-4-3-7-17(2)10-12/h4-6,8-9,16H,3,7,10H2,1-2H3
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 194n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286080
PNG
(CHEMBL103514 | N-[3-(1-Propyl-1,2,5,6-tetrahydro-p...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccc(NC(C)=O)cc12 |c:6|
Show InChI InChI=1S/C18H23N3O/c1-3-8-21-9-4-5-14(12-21)17-11-19-18-7-6-15(10-16(17)18)20-13(2)22/h5-7,10-11,19H,3-4,8-9,12H2,1-2H3,(H,20,22)
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 205n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286078
PNG
(3-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-ind...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccccc12 |c:5|
Show InChI InChI=1S/C15H18N2/c1-2-17-9-5-6-12(11-17)14-10-16-15-8-4-3-7-13(14)15/h3-4,6-8,10,16H,2,5,9,11H2,1H3
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 213n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286081
PNG
(3-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccc(cc12)C(=O)OC |c:6|
Show InChI InChI=1S/C18H22N2O2/c1-3-8-20-9-4-5-14(12-20)16-11-19-17-7-6-13(10-15(16)17)18(21)22-2/h5-7,10-11,19H,3-4,8-9,12H2,1-2H3
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 214n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286085
PNG
(5-Methoxy-3-(1-propyl-1,2,5,6-tetrahydro-pyridin-3...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccc(OC)cc12 |c:6|
Show InChI InChI=1S/C17H22N2O/c1-3-8-19-9-4-5-13(12-19)16-11-18-17-7-6-14(20-2)10-15(16)17/h5-7,10-11,18H,3-4,8-9,12H2,1-2H3
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 226n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286073
PNG
(5-Methoxy-3-(1,2,5,6-tetrahydro-pyridin-3-yl)-1H-i...)
Show SMILES COc1ccc2[nH]cc(C3=CCCNC3)c2c1 |t:9|
Show InChI InChI=1S/C14H16N2O/c1-17-11-4-5-14-12(7-11)13(9-16-14)10-3-2-6-15-8-10/h3-5,7,9,15-16H,2,6,8H2,1H3
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 230n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286077
PNG
(3-(1-Methyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(O)cc12 |c:4|
Show InChI InChI=1S/C14H16N2O/c1-16-6-2-3-10(9-16)13-8-15-14-5-4-11(17)7-12(13)14/h3-5,7-8,15,17H,2,6,9H2,1H3
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 237n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286095
PNG
(3-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-5-meth...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccc(C)cc12 |c:5|
Show InChI InChI=1S/C16H20N2/c1-3-18-8-4-5-13(11-18)15-10-17-16-7-6-12(2)9-14(15)16/h5-7,9-10,17H,3-4,8,11H2,1-2H3
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 246n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286096
PNG
(3-(1-Methyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccccc12 |c:4|
Show InChI InChI=1S/C14H16N2/c1-16-8-4-5-11(10-16)13-9-15-14-7-3-2-6-12(13)14/h2-3,5-7,9,15H,4,8,10H2,1H3
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 261n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286086
PNG
(3-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccc(cc12)C#N |c:6|
Show InChI InChI=1S/C17H19N3/c1-2-7-20-8-3-4-14(12-20)16-11-19-17-6-5-13(10-18)9-15(16)17/h4-6,9,11,19H,2-3,7-8,12H2,1H3
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 303n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286079
PNG
((4aS,11cS)-2-Methyl-2,3,4,4a,5,6,7,11c-octahydro-1...)
Show SMILES CN1CC[C@@H]2CCc3[nH]c4ccccc4c3[C@H]2C1
Show InChI InChI=1S/C16H20N2/c1-18-9-8-11-6-7-15-16(13(11)10-18)12-4-2-3-5-14(12)17-15/h2-5,11,13,17H,6-10H2,1H3/t11-,13-/m0/s1
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 325n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286090
PNG
(3-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccccc12 |c:6|
Show InChI InChI=1S/C16H20N2/c1-2-9-18-10-5-6-13(12-18)15-11-17-16-8-4-3-7-14(15)16/h3-4,6-8,11,17H,2,5,9-10,12H2,1H3
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 556n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286099
PNG
(5-Methoxy-3-(1-methyl-1,2,5,6-tetrahydro-pyridin-3...)
Show SMILES COc1ccc2[nH]cc(C3=CCCN(C)C3)c2c1 |t:9|
Show InChI InChI=1S/C15H18N2O/c1-17-7-3-4-11(10-17)14-9-16-15-6-5-12(18-2)8-13(14)15/h4-6,8-9,16H,3,7,10H2,1-2H3
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 716n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM81498
PNG
(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)
Show SMILES COc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:9|
Show InChI InChI=1S/C14H16N2O/c1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10/h2-4,8-9,15-16H,5-7H2,1H3
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 912n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for its binding affinity to Tested for its binding affinity to 5-hydroxytryptamine 2 receptor using [3H]-ketanserin radioligand assay using [3...

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286086
PNG
(3-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccc(cc12)C#N |c:6|
Show InChI InChI=1S/C17H19N3/c1-2-7-20-8-3-4-14(12-20)16-11-19-17-6-5-13(10-18)9-15(16)17/h4-6,9,11,19H,2-3,7-8,12H2,1H3
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 958n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286093
PNG
(3-(1-Methyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(cc12)C#N |c:4|
Show InChI InChI=1S/C15H15N3/c1-18-6-2-3-12(10-18)14-9-17-15-5-4-11(8-16)7-13(14)15/h3-5,7,9,17H,2,6,10H2,1H3
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 1.04E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286085
PNG
(5-Methoxy-3-(1-propyl-1,2,5,6-tetrahydro-pyridin-3...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccc(OC)cc12 |c:6|
Show InChI InChI=1S/C17H22N2O/c1-3-8-19-9-4-5-13(12-19)16-11-18-17-7-6-14(20-2)10-15(16)17/h5-7,10-11,18H,3-4,8-9,12H2,1-2H3
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 1.07E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286100
PNG
(3-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-5-meth...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccc(OC)cc12 |c:5|
Show InChI InChI=1S/C16H20N2O/c1-3-18-8-4-5-12(11-18)15-10-17-16-7-6-13(19-2)9-14(15)16/h5-7,9-10,17H,3-4,8,11H2,1-2H3
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 1.13E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286088
PNG
(3-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-ind...)
Show SMILES CCN1CCC=C(C1)c1c[nH]c2ccc(cc12)C#N |c:5|
Show InChI InChI=1S/C16H17N3/c1-2-19-7-3-4-13(11-19)15-10-18-16-6-5-12(9-17)8-14(15)16/h4-6,8,10,18H,2-3,7,11H2,1H3
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 1.36E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50286079
PNG
((4aS,11cS)-2-Methyl-2,3,4,4a,5,6,7,11c-octahydro-1...)
Show SMILES CN1CC[C@@H]2CCc3[nH]c4ccccc4c3[C@H]2C1
Show InChI InChI=1S/C16H20N2/c1-18-9-8-11-6-7-15-16(13(11)10-18)12-4-2-3-5-14(12)17-15/h2-5,11,13,17H,6-10H2,1H3/t11-,13-/m0/s1
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 2.36E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286094
PNG
(1-[3-(1-Methyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(cc12)C(C)=O |c:4|
Show InChI InChI=1S/C16H18N2O/c1-11(19)12-5-6-16-14(8-12)15(9-17-16)13-4-3-7-18(2)10-13/h4-6,8-9,17H,3,7,10H2,1-2H3
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 3.38E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286083
PNG
(3-(1-Methyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES COC(=O)c1ccc2[nH]cc(C3=CCCN(C)C3)c2c1 |t:11|
Show InChI InChI=1S/C16H18N2O2/c1-18-7-3-4-12(10-18)14-9-17-15-6-5-11(8-13(14)15)16(19)20-2/h4-6,8-9,17H,3,7,10H2,1-2H3
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 5.36E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286092
PNG
(3-(1-Methyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(cc12)C(N)=O |c:4|
Show InChI InChI=1S/C15H17N3O/c1-18-6-2-3-11(9-18)13-8-17-14-5-4-10(15(16)19)7-12(13)14/h3-5,7-8,17H,2,6,9H2,1H3,(H2,16,19)
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>1.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286089
PNG
(CHEMBL100814 | N-[3-(1-Methyl-1,2,5,6-tetrahydro-p...)
Show SMILES CN1CCC=C(C1)c1c[nH]c2ccc(NC(C)=O)cc12 |c:4|
Show InChI InChI=1S/C16H19N3O/c1-11(20)18-13-5-6-16-14(8-13)15(9-17-16)12-4-3-7-19(2)10-12/h4-6,8-9,17H,3,7,10H2,1-2H3,(H,18,20)
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 1.45E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286098
PNG
(3-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccc(cc12)C(N)=O |c:6|
Show InChI InChI=1S/C17H21N3O/c1-2-7-20-8-3-4-13(11-20)15-10-19-16-6-5-12(17(18)21)9-14(15)16/h4-6,9-10,19H,2-3,7-8,11H2,1H3,(H2,18,21)
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 1.92E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286080
PNG
(CHEMBL103514 | N-[3-(1-Propyl-1,2,5,6-tetrahydro-p...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccc(NC(C)=O)cc12 |c:6|
Show InChI InChI=1S/C18H23N3O/c1-3-8-21-9-4-5-14(12-21)17-11-19-18-7-6-15(10-16(17)18)20-13(2)22/h5-7,10-11,19H,3-4,8-9,12H2,1-2H3,(H,20,22)
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>5.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)		BDBM50286081
PNG
(3-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-1H-in...)
Show SMILES CCCN1CCC=C(C1)c1c[nH]c2ccc(cc12)C(=O)OC |c:6|
Show InChI InChI=1S/C18H22N2O2/c1-3-8-20-9-4-5-14(12-20)16-11-19-17-7-6-13(10-15(16)17)18(21)22-2/h5-7,10-11,19H,3-4,8-9,12H2,1-2H3
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>5.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 2 receptor using [3H]ketanserin radioligand assay.

Bioorg Med Chem Lett 5: 2963-2968 (1995)


Article DOI: 10.1016/0960-894X(95)00534-8
BindingDB Entry DOI: 10.7270/Q2862GD3
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%