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Articleid 50029731

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Substance-P receptor


(Homo sapiens (Human))		BDBM50287337
PNG
(CHEMBL291025 | N-[2-(3,5-Bis-trifluoromethyl-pheny...)
Show SMILES CN(CCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)CC(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C26H23F6NO/c1-33(13-12-18-14-21(25(27,28)29)16-22(15-18)26(30,31)32)24(34)17-23(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-11,14-16,23H,12-13,17H2,1H3
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n/an/a 10n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287354
PNG
(CHEMBL291074 | N-[2-(3,5-Bis-trifluoromethyl-pheny...)
Show SMILES CN(CCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C25H21F6NO/c1-32(13-12-17-14-20(24(26,27)28)16-21(15-17)25(29,30)31)23(33)22(18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-11,14-16,22H,12-13H2,1H3
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n/an/a 14n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287355
PNG
(CHEMBL288382 | N-(3,5-Dichloro-benzyl)-N-methyl-3,...)
Show SMILES CN(Cc1cc(Cl)cc(Cl)c1)C(=O)CC(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H21Cl2NO/c1-26(16-17-12-20(24)14-21(25)13-17)23(27)15-22(18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-14,22H,15-16H2,1H3
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n/an/a 45n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287345
PNG
(CHEMBL43085 | N-[2-(3,5-Bis-trifluoromethyl-phenyl...)
Show SMILES FC(F)(F)c1cc(CCNC(=O)C(c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C24H19F6NO/c25-23(26,27)19-13-16(14-20(15-19)24(28,29)30)11-12-31-22(32)21(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-10,13-15,21H,11-12H2,(H,31,32)
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n/an/a 46n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287349
PNG
(CHEMBL39089 | N-(3,5-Bis-trifluoromethyl-benzyl)-N...)
Show SMILES CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H19F6NO/c1-31(15-16-12-19(23(25,26)27)14-20(13-16)24(28,29)30)22(32)21(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-14,21H,15H2,1H3
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n/an/a 47n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287340
PNG
(CHEMBL40817 | N-(3,5-Bis-trifluoromethyl-benzyl)-N...)
Show SMILES CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)CC(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C25H21F6NO/c1-32(16-17-12-20(24(26,27)28)14-21(13-17)25(29,30)31)23(33)15-22(18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-14,22H,15-16H2,1H3
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n/an/a 56n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287358
PNG
(CHEMBL288340 | N-[2-(3,5-Bis-trifluoromethyl-pheny...)
Show SMILES FC(F)(F)c1cc(CCNC(=O)CC(c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C25H21F6NO/c26-24(27,28)20-13-17(14-21(15-20)25(29,30)31)11-12-32-23(33)16-22(18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-10,13-15,22H,11-12,16H2,(H,32,33)
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n/an/a 112n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287341
PNG
(2-(3,5-Bis-trifluoromethyl-phenyl)-N-(2,2-diphenyl...)
Show SMILES CN(CC(c1ccccc1)c1ccccc1)C(=O)Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C25H21F6NO/c1-32(16-22(18-8-4-2-5-9-18)19-10-6-3-7-11-19)23(33)14-17-12-20(24(26,27)28)15-21(13-17)25(29,30)31/h2-13,15,22H,14,16H2,1H3
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n/an/a 114n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287351
PNG
(CHEMBL41124 | N-(3,5-Bis-trifluoromethyl-phenyl)-N...)
Show SMILES CN(C(=O)CC(c1ccccc1)c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C24H19F6NO/c1-31(20-13-18(23(25,26)27)12-19(14-20)24(28,29)30)22(32)15-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-14,21H,15H2,1H3
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n/an/a 121n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287347
PNG
(CHEMBL436698 | N-(3,5-Dichloro-benzyl)-3,3-dipheny...)
Show SMILES Clc1cc(Cl)cc(CNC(=O)CC(c2ccccc2)c2ccccc2)c1
Show InChI InChI=1S/C22H19Cl2NO/c23-19-11-16(12-20(24)13-19)15-25-22(26)14-21(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-13,21H,14-15H2,(H,25,26)
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n/an/a 226n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287352
PNG
(CHEMBL417519 | N-(3,5-Dimethoxy-benzyl)-N-methyl-3...)
Show SMILES COc1cc(CN(C)C(=O)CC(c2ccccc2)c2ccccc2)cc(OC)c1
Show InChI InChI=1S/C25H27NO3/c1-26(18-19-14-22(28-2)16-23(15-19)29-3)25(27)17-24(20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-16,24H,17-18H2,1-3H3
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n/an/a 226n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287348
PNG
(CHEMBL289728 | N-(3,5-Bis-trifluoromethyl-benzyl)-...)
Show SMILES FC(F)(F)c1cc(CNC(=O)CC(c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C24H19F6NO/c25-23(26,27)19-11-16(12-20(13-19)24(28,29)30)15-31-22(32)14-21(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-13,21H,14-15H2,(H,31,32)
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n/an/a 235n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287357
PNG
(CHEMBL42972 | N-(2,2-Diphenyl-ethyl)-N-methyl-3,5-...)
Show SMILES CN(CC(c1ccccc1)c1ccccc1)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C24H19F6NO/c1-31(15-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17)22(32)18-12-19(23(25,26)27)14-20(13-18)24(28,29)30/h2-14,21H,15H2,1H3
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n/an/a 297n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287356
PNG
(CHEMBL40262 | N-(3,5-Bis-trifluoromethyl-phenyl)-N...)
Show SMILES CN(C(=O)C(c1ccccc1)c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C23H17F6NO/c1-30(19-13-17(22(24,25)26)12-18(14-19)23(27,28)29)21(31)20(15-8-4-2-5-9-15)16-10-6-3-7-11-16/h2-14,20H,1H3
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n/an/a 301n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287350
PNG
(CHEMBL41705 | N-[3-(3,5-Bis-trifluoromethyl-phenyl...)
Show SMILES CN(CCCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)CC(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H25F6NO/c1-34(14-8-9-19-15-22(26(28,29)30)17-23(16-19)27(31,32)33)25(35)18-24(20-10-4-2-5-11-20)21-12-6-3-7-13-21/h2-7,10-13,15-17,24H,8-9,14,18H2,1H3
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n/an/a 304n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287335
PNG
(CHEMBL40620 | N-[3-(3,5-Bis-trifluoromethyl-phenyl...)
Show SMILES CN(CCCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C26H23F6NO/c1-33(24(34)23(19-10-4-2-5-11-19)20-12-6-3-7-13-20)14-8-9-18-15-21(25(27,28)29)17-22(16-18)26(30,31)32/h2-7,10-13,15-17,23H,8-9,14H2,1H3
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n/an/a 323n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287343
PNG
(2-(3,5-Bis-trifluoromethyl-phenyl)-N-(2,2-diphenyl...)
Show SMILES FC(F)(F)c1cc(CC(=O)NCC(c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C24H19F6NO/c25-23(26,27)19-11-16(12-20(14-19)24(28,29)30)13-22(32)31-15-21(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-12,14,21H,13,15H2,(H,31,32)
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n/an/a 378n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287336
PNG
(CHEMBL43027 | N-(3,5-Bis-trifluoromethyl-benzyl)-2...)
Show SMILES FC(F)(F)c1cc(CNC(=O)C(c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C23H17F6NO/c24-22(25,26)18-11-15(12-19(13-18)23(27,28)29)14-30-21(31)20(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-13,20H,14H2,(H,30,31)
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n/an/a 526n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287342
PNG
(CHEMBL417881 | N-[3-(3,5-Bis-trifluoromethyl-pheny...)
Show SMILES FC(F)(F)c1cc(CCCNC(=O)C(c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C25H21F6NO/c26-24(27,28)20-14-17(15-21(16-20)25(29,30)31)8-7-13-32-23(33)22(18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-6,9-12,14-16,22H,7-8,13H2,(H,32,33)
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n/an/a 593n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287353
PNG
(CHEMBL417522 | N-[3-(3,5-Bis-trifluoromethyl-pheny...)
Show SMILES FC(F)(F)c1cc(CCCNC(=O)CC(c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C26H23F6NO/c27-25(28,29)21-14-18(15-22(16-21)26(30,31)32)8-7-13-33-24(34)17-23(19-9-3-1-4-10-19)20-11-5-2-6-12-20/h1-6,9-12,14-16,23H,7-8,13,17H2,(H,33,34)
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n/an/a 620n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287338
PNG
(CHEMBL40164 | N-(3,5-Dimethoxy-benzyl)-3,3-dipheny...)
Show SMILES COc1cc(CNC(=O)CC(c2ccccc2)c2ccccc2)cc(OC)c1
Show InChI InChI=1S/C24H25NO3/c1-27-21-13-18(14-22(15-21)28-2)17-25-24(26)16-23(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-15,23H,16-17H2,1-2H3,(H,25,26)
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n/an/a 2.24E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287339
PNG
(CHEMBL40969 | N-(3,5-Bis-trifluoromethyl-phenyl)-3...)
Show SMILES FC(F)(F)c1cc(NC(=O)CC(c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C23H17F6NO/c24-22(25,26)17-11-18(23(27,28)29)13-19(12-17)30-21(31)14-20(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,20H,14H2,(H,30,31)
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n/an/a 3.01E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287344
PNG
(CHEMBL40587 | N-(2,2-Diphenyl-ethyl)-3,5-bis-trifl...)
Show SMILES FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)NCC(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H17F6NO/c24-22(25,26)18-11-17(12-19(13-18)23(27,28)29)21(31)30-14-20(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,20H,14H2,(H,30,31)
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n/an/a 3.92E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
Substance-P receptor


(Homo sapiens (Human))		BDBM50287346
PNG
(CHEMBL41762 | N-(3,5-Bis-trifluoromethyl-phenyl)-2...)
Show SMILES FC(F)(F)c1cc(NC(=O)C(c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C22H15F6NO/c23-21(24,25)16-11-17(22(26,27)28)13-18(12-16)29-20(30)19(14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-13,19H,(H,29,30)
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n/an/a 6.56E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%