Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neprilysin (Rattus norvegicus (Rat)) | BDBM50024096 (((R)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of rat kidney neutral endopeptidase | Bioorg Med Chem Lett 6: 2097-2102 (1996) Article DOI: 10.1016/0960-894X(96)00375-7 BindingDB Entry DOI: 10.7270/Q2X92B8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Rattus norvegicus (Rat)) | BDBM50024102 (((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of rat kidney neutral endopeptidase | Bioorg Med Chem Lett 6: 2097-2102 (1996) Article DOI: 10.1016/0960-894X(96)00375-7 BindingDB Entry DOI: 10.7270/Q2X92B8K | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Neprilysin (Rattus norvegicus (Rat)) | BDBM50287697 ((4S,7S)-7-Mercaptomethyl-6-oxo-1,2,3,4,6,7,8,12b-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of rat kidney neutral endopeptidase | Bioorg Med Chem Lett 6: 2097-2102 (1996) Article DOI: 10.1016/0960-894X(96)00375-7 BindingDB Entry DOI: 10.7270/Q2X92B8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Rattus norvegicus (Rat)) | BDBM50287716 (CHEMBL63704 | [((1S,2R,5S)-2-Mercapto-5-phenyl-cyc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of rat kidney neutral endopeptidase | Bioorg Med Chem Lett 6: 2097-2102 (1996) Article DOI: 10.1016/0960-894X(96)00375-7 BindingDB Entry DOI: 10.7270/Q2X92B8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Rattus norvegicus (Rat)) | BDBM50287717 (CHEMBL67069 | [((1R,2S,5R)-2-Mercapto-5-phenyl-cyc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of rat kidney neutral endopeptidase | Bioorg Med Chem Lett 6: 2097-2102 (1996) Article DOI: 10.1016/0960-894X(96)00375-7 BindingDB Entry DOI: 10.7270/Q2X92B8K | |||||||||||
More data for this Ligand-Target Pair |