Found 26 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289733
(1-(2,5-Dimethoxy-benzyl)-6-ethoxy-4-(4-methoxy-phe...)Show SMILES CCOc1ccc2n(Cc3cc(OC)ccc3OC)c(=O)c(C(O)=O)c(-c3ccc(OC)cc3)c2c1 Show InChI InChI=1S/C28H27NO7/c1-5-36-21-10-12-23-22(15-21)25(17-6-8-19(33-2)9-7-17)26(28(31)32)27(30)29(23)16-18-14-20(34-3)11-13-24(18)35-4/h6-15H,5,16H2,1-4H3,(H,31,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289733
(1-(2,5-Dimethoxy-benzyl)-6-ethoxy-4-(4-methoxy-phe...)Show SMILES CCOc1ccc2n(Cc3cc(OC)ccc3OC)c(=O)c(C(O)=O)c(-c3ccc(OC)cc3)c2c1 Show InChI InChI=1S/C28H27NO7/c1-5-36-21-10-12-23-22(15-21)25(17-6-8-19(33-2)9-7-17)26(28(31)32)27(30)29(23)16-18-14-20(34-3)11-13-24(18)35-4/h6-15H,5,16H2,1-4H3,(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289739
(4-Benzo[1,3]dioxol-5-yl-6-ethoxy-1-(2-methoxy-benz...)Show SMILES CCOc1ccc2n(Cc3ccccc3OC)c(=O)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C27H23NO7/c1-3-33-18-9-10-20-19(13-18)24(16-8-11-22-23(12-16)35-15-34-22)25(27(30)31)26(29)28(20)14-17-6-4-5-7-21(17)32-2/h4-13H,3,14-15H2,1-2H3,(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289739
(4-Benzo[1,3]dioxol-5-yl-6-ethoxy-1-(2-methoxy-benz...)Show SMILES CCOc1ccc2n(Cc3ccccc3OC)c(=O)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C27H23NO7/c1-3-33-18-9-10-20-19(13-18)24(16-8-11-22-23(12-16)35-15-34-22)25(27(30)31)26(29)28(20)14-17-6-4-5-7-21(17)32-2/h4-13H,3,14-15H2,1-2H3,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289738
(6-Ethoxy-1-(2-methoxy-benzyl)-4-(4-methoxy-phenyl)...)Show SMILES CCOc1ccc2n(Cc3ccccc3OC)c(=O)c(C(O)=O)c(-c3ccc(OC)cc3)c2c1 Show InChI InChI=1S/C27H25NO6/c1-4-34-20-13-14-22-21(15-20)24(17-9-11-19(32-2)12-10-17)25(27(30)31)26(29)28(22)16-18-7-5-6-8-23(18)33-3/h5-15H,4,16H2,1-3H3,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289737
(4-(2,4-Dimethoxy-phenyl)-6-ethoxy-1-(2-methoxy-ben...)Show SMILES CCOc1ccc2n(Cc3ccccc3OC)c(=O)c(C(O)=O)c(-c3ccc(OC)cc3OC)c2c1 |(-3.49,-2.11,;-2.16,-2.88,;-2.16,-4.42,;-.83,-5.19,;-.83,-6.73,;.5,-7.5,;1.83,-6.73,;3.17,-7.5,;3.16,-9.04,;4.49,-9.81,;5.82,-9.04,;7.15,-9.81,;7.15,-11.36,;5.82,-12.12,;4.49,-11.35,;3.16,-12.12,;1.82,-11.35,;4.51,-6.73,;5.84,-7.5,;4.51,-5.19,;5.84,-4.42,;7.17,-5.19,;5.84,-2.88,;3.17,-4.41,;3.17,-2.88,;4.51,-2.11,;4.5,-.57,;3.18,.2,;3.17,1.74,;4.51,2.51,;1.84,-.57,;1.83,-2.11,;.5,-2.88,;-.83,-2.11,;1.84,-5.19,;.5,-4.42,)| Show InChI InChI=1S/C28H27NO7/c1-5-36-19-11-13-22-21(14-19)25(20-12-10-18(33-2)15-24(20)35-4)26(28(31)32)27(30)29(22)16-17-8-6-7-9-23(17)34-3/h6-15H,5,16H2,1-4H3,(H,31,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289730
(4-Benzo[1,3]dioxol-5-yl-1-(2-methoxy-benzyl)-2-oxo...)Show SMILES COc1ccccc1Cn1c2ccccc2c(-c2ccc3OCOc3c2)c(C(O)=O)c1=O Show InChI InChI=1S/C25H19NO6/c1-30-19-9-5-2-6-16(19)13-26-18-8-4-3-7-17(18)22(23(24(26)27)25(28)29)15-10-11-20-21(12-15)32-14-31-20/h2-12H,13-14H2,1H3,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 940 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289737
(4-(2,4-Dimethoxy-phenyl)-6-ethoxy-1-(2-methoxy-ben...)Show SMILES CCOc1ccc2n(Cc3ccccc3OC)c(=O)c(C(O)=O)c(-c3ccc(OC)cc3OC)c2c1 |(-3.49,-2.11,;-2.16,-2.88,;-2.16,-4.42,;-.83,-5.19,;-.83,-6.73,;.5,-7.5,;1.83,-6.73,;3.17,-7.5,;3.16,-9.04,;4.49,-9.81,;5.82,-9.04,;7.15,-9.81,;7.15,-11.36,;5.82,-12.12,;4.49,-11.35,;3.16,-12.12,;1.82,-11.35,;4.51,-6.73,;5.84,-7.5,;4.51,-5.19,;5.84,-4.42,;7.17,-5.19,;5.84,-2.88,;3.17,-4.41,;3.17,-2.88,;4.51,-2.11,;4.5,-.57,;3.18,.2,;3.17,1.74,;4.51,2.51,;1.84,-.57,;1.83,-2.11,;.5,-2.88,;-.83,-2.11,;1.84,-5.19,;.5,-4.42,)| Show InChI InChI=1S/C28H27NO7/c1-5-36-19-11-13-22-21(14-19)25(20-12-10-18(33-2)15-24(20)35-4)26(28(31)32)27(30)29(22)16-17-8-6-7-9-23(17)34-3/h6-15H,5,16H2,1-4H3,(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289732
(4-Benzo[1,3]dioxol-5-yl-6-ethyl-1-(2-methoxy-benzy...)Show SMILES CCc1ccc2n(Cc3ccccc3OC)c(=O)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C27H23NO6/c1-3-16-8-10-20-19(12-16)24(17-9-11-22-23(13-17)34-15-33-22)25(27(30)31)26(29)28(20)14-18-6-4-5-7-21(18)32-2/h4-13H,3,14-15H2,1-2H3,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289738
(6-Ethoxy-1-(2-methoxy-benzyl)-4-(4-methoxy-phenyl)...)Show SMILES CCOc1ccc2n(Cc3ccccc3OC)c(=O)c(C(O)=O)c(-c3ccc(OC)cc3)c2c1 Show InChI InChI=1S/C27H25NO6/c1-4-34-20-13-14-22-21(15-20)24(17-9-11-19(32-2)12-10-17)25(27(30)31)26(29)28(22)16-18-7-5-6-8-23(18)33-3/h5-15H,4,16H2,1-3H3,(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289732
(4-Benzo[1,3]dioxol-5-yl-6-ethyl-1-(2-methoxy-benzy...)Show SMILES CCc1ccc2n(Cc3ccccc3OC)c(=O)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C27H23NO6/c1-3-16-8-10-20-19(12-16)24(17-9-11-22-23(13-17)34-15-33-22)25(27(30)31)26(29)28(20)14-18-6-4-5-7-21(18)32-2/h4-13H,3,14-15H2,1-2H3,(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289730
(4-Benzo[1,3]dioxol-5-yl-1-(2-methoxy-benzyl)-2-oxo...)Show SMILES COc1ccccc1Cn1c2ccccc2c(-c2ccc3OCOc3c2)c(C(O)=O)c1=O Show InChI InChI=1S/C25H19NO6/c1-30-19-9-5-2-6-16(19)13-26-18-8-4-3-7-17(18)22(23(24(26)27)25(28)29)15-10-11-20-21(12-15)32-14-31-20/h2-12H,13-14H2,1H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289734
(4-Benzo[1,3]dioxol-5-yl-1-(4-methoxy-benzyl)-2-oxo...)Show SMILES COc1ccc(Cn2c3ccccc3c(-c3ccc4OCOc4c3)c(C(O)=O)c2=O)cc1 Show InChI InChI=1S/C25H19NO6/c1-30-17-9-6-15(7-10-17)13-26-19-5-3-2-4-18(19)22(23(24(26)27)25(28)29)16-8-11-20-21(12-16)32-14-31-20/h2-12H,13-14H2,1H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289731
(4-Benzo[1,3]dioxol-5-yl-5,6-dimethoxy-1-(2-methoxy...)Show SMILES COc1ccccc1Cn1c2ccc(OC)c(OC)c2c(-c2ccc3OCOc3c2)c(C(O)=O)c1=O Show InChI InChI=1S/C27H23NO8/c1-32-18-7-5-4-6-16(18)13-28-17-9-11-20(33-2)25(34-3)23(17)22(24(26(28)29)27(30)31)15-8-10-19-21(12-15)36-14-35-19/h4-12H,13-14H2,1-3H3,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289728
(4-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)Show SMILES OC(=O)c1c(-c2ccc3OCOc3c2)c2ccccc2n(Cc2ccc3OCOc3c2)c1=O Show InChI InChI=1S/C25H17NO7/c27-24-23(25(28)29)22(15-6-8-19-21(10-15)33-13-31-19)16-3-1-2-4-17(16)26(24)11-14-5-7-18-20(9-14)32-12-30-18/h1-10H,11-13H2,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289728
(4-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)Show SMILES OC(=O)c1c(-c2ccc3OCOc3c2)c2ccccc2n(Cc2ccc3OCOc3c2)c1=O Show InChI InChI=1S/C25H17NO7/c27-24-23(25(28)29)22(15-6-8-19-21(10-15)33-13-31-19)16-3-1-2-4-17(16)26(24)11-14-5-7-18-20(9-14)32-12-30-18/h1-10H,11-13H2,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289731
(4-Benzo[1,3]dioxol-5-yl-5,6-dimethoxy-1-(2-methoxy...)Show SMILES COc1ccccc1Cn1c2ccc(OC)c(OC)c2c(-c2ccc3OCOc3c2)c(C(O)=O)c1=O Show InChI InChI=1S/C27H23NO8/c1-32-18-7-5-4-6-16(18)13-28-17-9-11-20(33-2)25(34-3)23(17)22(24(26(28)29)27(30)31)15-8-10-19-21(12-15)36-14-35-19/h4-12H,13-14H2,1-3H3,(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289734
(4-Benzo[1,3]dioxol-5-yl-1-(4-methoxy-benzyl)-2-oxo...)Show SMILES COc1ccc(Cn2c3ccccc3c(-c3ccc4OCOc4c3)c(C(O)=O)c2=O)cc1 Show InChI InChI=1S/C25H19NO6/c1-30-17-9-6-15(7-10-17)13-26-19-5-3-2-4-18(19)22(23(24(26)27)25(28)29)16-8-11-20-21(12-16)32-14-31-20/h2-12H,13-14H2,1H3,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289735
(4-Benzo[1,3]dioxol-5-yl-1-benzyl-2-oxo-1,2-dihydro...)Show SMILES OC(=O)c1c(-c2ccc3OCOc3c2)c2ccccc2n(Cc2ccccc2)c1=O Show InChI InChI=1S/C24H17NO5/c26-23-22(24(27)28)21(16-10-11-19-20(12-16)30-14-29-19)17-8-4-5-9-18(17)25(23)13-15-6-2-1-3-7-15/h1-12H,13-14H2,(H,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289736
(CHEMBL56349 | [4-Benzo[1,3]dioxol-5-yl-1-(2-methox...)Show SMILES COc1ccccc1Cn1c2ccccc2c(-c2ccc3OCOc3c2)c(CC(O)=O)c1=O Show InChI InChI=1S/C26H21NO6/c1-31-21-9-5-2-6-17(21)14-27-20-8-4-3-7-18(20)25(19(26(27)30)13-24(28)29)16-10-11-22-23(12-16)33-15-32-22/h2-12H,13-15H2,1H3,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289736
(CHEMBL56349 | [4-Benzo[1,3]dioxol-5-yl-1-(2-methox...)Show SMILES COc1ccccc1Cn1c2ccccc2c(-c2ccc3OCOc3c2)c(CC(O)=O)c1=O Show InChI InChI=1S/C26H21NO6/c1-31-21-9-5-2-6-17(21)14-27-20-8-4-3-7-18(20)25(19(26(27)30)13-24(28)29)16-10-11-22-23(12-16)33-15-32-22/h2-12H,13-15H2,1H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289740
(4-Benzo[1,3]dioxol-5-yl-1-(3-methoxy-benzyl)-2-oxo...)Show SMILES COc1cccc(Cn2c3ccccc3c(-c3ccc4OCOc4c3)c(C(O)=O)c2=O)c1 Show InChI InChI=1S/C25H19NO6/c1-30-17-6-4-5-15(11-17)13-26-19-8-3-2-7-18(19)22(23(24(26)27)25(28)29)16-9-10-20-21(12-16)32-14-31-20/h2-12H,13-14H2,1H3,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289740
(4-Benzo[1,3]dioxol-5-yl-1-(3-methoxy-benzyl)-2-oxo...)Show SMILES COc1cccc(Cn2c3ccccc3c(-c3ccc4OCOc4c3)c(C(O)=O)c2=O)c1 Show InChI InChI=1S/C25H19NO6/c1-30-17-6-4-5-15(11-17)13-26-19-8-3-2-7-18(19)22(23(24(26)27)25(28)29)16-9-10-20-21(12-16)32-14-31-20/h2-12H,13-14H2,1H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289735
(4-Benzo[1,3]dioxol-5-yl-1-benzyl-2-oxo-1,2-dihydro...)Show SMILES OC(=O)c1c(-c2ccc3OCOc3c2)c2ccccc2n(Cc2ccccc2)c1=O Show InChI InChI=1S/C24H17NO5/c26-23-22(24(27)28)21(16-10-11-19-20(12-16)30-14-29-19)17-8-4-5-9-18(17)25(23)13-15-6-2-1-3-7-15/h1-12H,13-14H2,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin-1 receptor
(RAT) | BDBM50289729
(3-Benzo[1,3]dioxol-5-yl-5-ethoxy-1-(4-methoxy-benz...)Show SMILES CCOc1ccc2n(Cc3ccc(OC)cc3)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C26H23NO6/c1-3-31-19-9-10-21-20(13-19)24(17-6-11-22-23(12-17)33-15-32-22)25(26(28)29)27(21)14-16-4-7-18(30-2)8-5-16/h4-13H,3,14-15H2,1-2H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to rat aorta membranes(ETA) |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B
(Homo sapiens (Human)) | BDBM50289729
(3-Benzo[1,3]dioxol-5-yl-5-ethoxy-1-(4-methoxy-benz...)Show SMILES CCOc1ccc2n(Cc3ccc(OC)cc3)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C26H23NO6/c1-3-31-19-9-10-21-20(13-19)24(17-6-11-22-23(12-17)33-15-32-22)25(26(28)29)27(21)14-16-4-7-18(30-2)8-5-16/h4-13H,3,14-15H2,1-2H3,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membranes |
Bioorg Med Chem Lett 7: 1883-1886 (1997)
Article DOI: 10.1016/S0960-894X(97)00319-3
BindingDB Entry DOI: 10.7270/Q2FF3SCQ |
More data for this
Ligand-Target Pair | |
Search and Browse
