Affinity Data by PubMed id=7650683

PubMed code 7650683

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50032951 (5-(piperidin-4-yl)isothiazol-3-ol \| 5-Piperidin-4-...) Show SMILES O=c1cc(s[nH]1)C1CCNCC1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM82002 (CAS_64603-91-4 \| NSC_3448 \| THIP) Show SMILES O=c1[nH]oc2CNCCc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50032956 (3-Piperidin-4-yl-isoxazol-5-ol \| CHEMBL110210) Show SMILES O=c1cc([nH]o1)C1CCNCC1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50032957 ((E)-3-Piperidin-4-yl-acrylic acid \| CHEMBL113450) Show SMILES OC(=O)\C=C\C1CCNCC1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50032953 (3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-propionic acid...) Show SMILES OC(=O)CCC1=CCNCC1 \|t:5\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50032949 (3-Piperidin-4-yl-propionic acid \| CHEMBL110858) Show SMILES OC(=O)CCC1CCNCC1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50032954 (5-(piperidin-4-yl)isoxazol-3-ol \| 5-Piperidin-4-yl...) Show SMILES O=c1cc(o[nH]1)C1CCNCC1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50032955 (1,2,3,6-Tetrahydro-pyridine-4-carboxylic acid \| 1,...) Show SMILES OC(=O)C1=CCNCC1 \|t:3\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50032950 (5-(1,2,3,6-Tetrahydro-pyridin-4-yl)-isothiazol-3-o...) Show SMILES O=c1cc(s[nH]1)C1=CCNCC1 \|t:7\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50032952 ((E)-3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-acrylic ac...) Show SMILES OC(=O)\C=C\C1=CCNCC1 \|t:5\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50032948 (5-(1,2,3,6-Tetrahydro-pyridin-4-yl)-isoxazol-3-ol ...) Show SMILES O=c1cc(o[nH]1)C1=CCNCC1 \|t:7\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%