Affinity Data by PubMed id=8258828

PubMed code 8258828

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thromboxane-A synthase (Rattus norvegicus)	BDBM50017896 ((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...) Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in rat whole blood				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50017896 ((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...) Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in rat platelet				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017896 ((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...) Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in human platelet				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50043282 (2-Methyl-4-thiazol-5-yl-2H-phthalazin-1-one \| CHEM...) Show SMILES Cn1nc(-c2cncs2)c2ccccc2c1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in rat platelet				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017896 ((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...) Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in human platelet				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50043282 (2-Methyl-4-thiazol-5-yl-2H-phthalazin-1-one \| CHEM...) Show SMILES Cn1nc(-c2cncs2)c2ccccc2c1=O Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in human platelet				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017896 ((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...) Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in human whole blood				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50043283 (2-Ethyl-4-pyridin-3-yl-2H-phthalazin-1-one \| CHEMB...) Show SMILES CCn1nc(-c2cccnc2)c2ccccc2c1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in rat platelet				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50043283 (2-Ethyl-4-pyridin-3-yl-2H-phthalazin-1-one \| CHEMB...) Show SMILES CCn1nc(-c2cccnc2)c2ccccc2c1=O Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in human microsome				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50043283 (2-Ethyl-4-pyridin-3-yl-2H-phthalazin-1-one \| CHEMB...) Show SMILES CCn1nc(-c2cccnc2)c2ccccc2c1=O Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in human microsome				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50043283 (2-Ethyl-4-pyridin-3-yl-2H-phthalazin-1-one \| CHEMB...) Show SMILES CCn1nc(-c2cccnc2)c2ccccc2c1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in rat whole blood				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50043283 (2-Ethyl-4-pyridin-3-yl-2H-phthalazin-1-one \| CHEMB...) Show SMILES CCn1nc(-c2cccnc2)c2ccccc2c1=O Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in human whole blood				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50043282 (2-Methyl-4-thiazol-5-yl-2H-phthalazin-1-one \| CHEM...) Show SMILES Cn1nc(-c2cncs2)c2ccccc2c1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in rat whole blood				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50043282 (2-Methyl-4-thiazol-5-yl-2H-phthalazin-1-one \| CHEM...) Show SMILES Cn1nc(-c2cncs2)c2ccccc2c1=O Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in human microsome				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50043282 (2-Methyl-4-thiazol-5-yl-2H-phthalazin-1-one \| CHEM...) Show SMILES Cn1nc(-c2cncs2)c2ccccc2c1=O Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Tested in vitro against TXA2 synthetase inhibitory activity in human whole blood				J Med Chem 36: 4061-8 (1994) BindingDB Entry DOI: 10.7270/Q2QJ7GBK
Chugai Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%