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PubMed code 8340921

Compile data set for download or QSAR
Found 43 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044403
PNG
(2-Methoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylme...)
Show SMILES COc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C23H18N6O3/c1-32-23-24-19-8-4-7-18(22(30)31)20(19)29(23)13-14-9-11-15(12-10-14)16-5-2-3-6-17(16)21-25-27-28-26-21/h2-12H,13H2,1H3,(H,30,31)(H,25,26,27,28)
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n/an/a 32n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044379
PNG
(2-Propylamino-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-...)
Show SMILES CCCNc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H23N7O2/c1-2-14-26-25-27-21-9-5-8-20(24(33)34)22(21)32(25)15-16-10-12-17(13-11-16)18-6-3-4-7-19(18)23-28-30-31-29-23/h3-13H,2,14-15H2,1H3,(H,26,27)(H,33,34)(H,28,29,30,31)
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n/an/a 39n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044410
PNG
(2-Ethyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Show SMILES CCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C24H20N6O2/c1-2-21-25-20-9-5-8-19(24(31)32)22(20)30(21)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)23-26-28-29-27-23/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)
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n/an/a 46n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044414
PNG
(2-Ethylamino-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-y...)
Show SMILES CCNc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C24H21N7O2/c1-2-25-24-26-20-9-5-8-19(23(32)33)21(20)31(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-27-29-30-28-22/h3-13H,2,14H2,1H3,(H,25,26)(H,32,33)(H,27,28,29,30)
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n/an/a 62n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044396
PNG
(2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Show SMILES CCOc1nc2cccc(C(=O)OC)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H22N6O3/c1-3-34-25-26-21-10-6-9-20(24(32)33-2)22(21)31(25)15-16-11-13-17(14-12-16)18-7-4-5-8-19(18)23-27-29-30-28-23/h4-14H,3,15H2,1-2H3,(H,27,28,29,30)
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n/an/a 66n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044386
PNG
(2-Isopropyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl...)
Show SMILES CC(C)c1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H22N6O2/c1-15(2)24-26-21-9-5-8-20(25(32)33)22(21)31(24)14-16-10-12-17(13-11-16)18-6-3-4-7-19(18)23-27-29-30-28-23/h3-13,15H,14H2,1-2H3,(H,32,33)(H,27,28,29,30)
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n/an/a 82n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044389
PNG
(2-Cyclopropyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-...)
Show SMILES OC(=O)c1cccc2nc(C3CC3)n(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c12
Show InChI InChI=1S/C25H20N6O2/c32-25(33)20-6-3-7-21-22(20)31(24(26-21)17-12-13-17)14-15-8-10-16(11-9-15)18-4-1-2-5-19(18)23-27-29-30-28-23/h1-11,17H,12-14H2,(H,32,33)(H,27,28,29,30)
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n/an/a 84n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044388
PNG
(2-Ethanesulfinyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Show SMILES CCS(=O)c1nc2cccc(C(=O)OC)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H22N6O3S/c1-3-35(33)25-26-21-10-6-9-20(24(32)34-2)22(21)31(25)15-16-11-13-17(14-12-16)18-7-4-5-8-19(18)23-27-29-30-28-23/h4-14H,3,15H2,1-2H3,(H,27,28,29,30)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50240609
PNG
(2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Show SMILES CCOc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044413
PNG
(2-Propylsulfanyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Show SMILES CCCSc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H22N6O2S/c1-2-14-34-25-26-21-9-5-8-20(24(32)33)22(21)31(25)15-16-10-12-17(13-11-16)18-6-3-4-7-19(18)23-27-29-30-28-23/h3-13H,2,14-15H2,1H3,(H,32,33)(H,27,28,29,30)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044377
PNG
(2-Methylsulfanyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Show SMILES CSc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C23H18N6O2S/c1-32-23-24-19-8-4-7-18(22(30)31)20(19)29(23)13-14-9-11-15(12-10-14)16-5-2-3-6-17(16)21-25-27-28-26-21/h2-12H,13H2,1H3,(H,30,31)(H,25,26,27,28)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50406795
PNG
(Cozaar | LOSARTAN POTASSIUM)
Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nn[n-]n1
Show InChI InChI=1S/C22H22ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3/q-1
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044406
PNG
(2-Methylsulfanylmethyl-3-[2'-(1H-tetrazol-5-yl)-bi...)
Show SMILES CSCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C24H20N6O2S/c1-33-14-21-25-20-8-4-7-19(24(31)32)22(20)30(21)13-15-9-11-16(12-10-15)17-5-2-3-6-18(17)23-26-28-29-27-23/h2-12H,13-14H2,1H3,(H,31,32)(H,26,27,28,29)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044375
PNG
(2-Propyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Show SMILES CCCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H22N6O2/c1-2-6-22-26-21-10-5-9-20(25(32)33)23(21)31(22)15-16-11-13-17(14-12-16)18-7-3-4-8-19(18)24-27-29-30-28-24/h3-5,7-14H,2,6,15H2,1H3,(H,32,33)(H,27,28,29,30)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044382
PNG
(2-Ethylsulfanyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-...)
Show SMILES CCSc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C24H20N6O2S/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044408
PNG
(2-Methylamino-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-...)
Show SMILES CNc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C23H19N7O2/c1-24-23-25-19-8-4-7-18(22(31)32)20(19)30(23)13-14-9-11-15(12-10-14)16-5-2-3-6-17(16)21-26-28-29-27-21/h2-12H,13H2,1H3,(H,24,25)(H,31,32)(H,26,27,28,29)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044391
PNG
(2-Methyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Show SMILES Cc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C23H18N6O2/c1-14-24-20-8-4-7-19(23(30)31)21(20)29(14)13-15-9-11-16(12-10-15)17-5-2-3-6-18(17)22-25-27-28-26-22/h2-12H,13H2,1H3,(H,30,31)(H,25,26,27,28)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044405
PNG
(2-Propoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylme...)
Show SMILES CCCOc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H22N6O3/c1-2-14-34-25-26-21-9-5-8-20(24(32)33)22(21)31(25)15-16-10-12-17(13-11-16)18-6-3-4-7-19(18)23-27-29-30-28-23/h3-13H,2,14-15H2,1H3,(H,32,33)(H,27,28,29,30)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044407
PNG
(3-(2'-Carboxy-biphenyl-4-ylmethyl)-2-ethoxy-3H-ben...)
Show SMILES CCOc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C24H20N2O5/c1-2-31-24-25-20-9-5-8-19(23(29)30)21(20)26(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22(27)28/h3-13H,2,14H2,1H3,(H,27,28)(H,29,30)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044387
PNG
(2-Methoxymethyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-...)
Show SMILES COCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C24H20N6O3/c1-33-14-21-25-20-8-4-7-19(24(31)32)22(20)30(21)13-15-9-11-16(12-10-15)17-5-2-3-6-18(17)23-26-28-29-27-23/h2-12H,13-14H2,1H3,(H,31,32)(H,26,27,28,29)
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n/an/a 250n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044409
PNG
(2-Ethylsulfanylmethyl-3-[2'-(1H-tetrazol-5-yl)-bip...)
Show SMILES CCSCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H22N6O2S/c1-2-34-15-22-26-21-9-5-8-20(25(32)33)23(21)31(22)14-16-10-12-17(13-11-16)18-6-3-4-7-19(18)24-27-29-30-28-24/h3-13H,2,14-15H2,1H3,(H,32,33)(H,27,28,29,30)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044411
PNG
(2-Ethoxymethyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4...)
Show SMILES CCOCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H22N6O3/c1-2-34-15-22-26-21-9-5-8-20(25(32)33)23(21)31(22)14-16-10-12-17(13-11-16)18-6-3-4-7-19(18)24-27-29-30-28-24/h3-13H,2,14-15H2,1H3,(H,32,33)(H,27,28,29,30)
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n/an/a 440n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044378
PNG
(2-Ethylsulfanyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-...)
Show SMILES CCSc1nc2cccc(C(=O)OC)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H22N6O2S/c1-3-34-25-26-21-10-6-9-20(24(32)33-2)22(21)31(25)15-16-11-13-17(14-12-16)18-7-4-5-8-19(18)23-27-29-30-28-23/h4-14H,3,15H2,1-2H3,(H,27,28,29,30)
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n/an/a 440n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044390
PNG
(2-Methoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylme...)
Show SMILES COC(=O)c1cccc2nc(OC)n(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c12
Show InChI InChI=1S/C24H20N6O3/c1-32-23(31)19-8-5-9-20-21(19)30(24(25-20)33-2)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,14H2,1-2H3,(H,26,27,28,29)
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n/an/a 490n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044402
PNG
(2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Show SMILES CCCCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C26H24N6O2/c1-2-3-11-23-27-22-10-6-9-21(26(33)34)24(22)32(23)16-17-12-14-18(15-13-17)19-7-4-5-8-20(19)25-28-30-31-29-25/h4-10,12-15H,2-3,11,16H2,1H3,(H,33,34)(H,28,29,30,31)
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n/an/a 550n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044376
PNG
(2-Pentyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Show SMILES CCCCCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C27H26N6O2/c1-2-3-4-12-24-28-23-11-7-10-22(27(34)35)25(23)33(24)17-18-13-15-19(16-14-18)20-8-5-6-9-21(20)26-29-31-32-30-26/h5-11,13-16H,2-4,12,17H2,1H3,(H,34,35)(H,29,30,31,32)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044381
PNG
(3-[2'-(1H-Tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-(2...)
Show SMILES OC(=O)c1cccc2nc(OCC(F)(F)F)n(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c12
Show InChI InChI=1S/C24H17F3N6O3/c25-24(26,27)13-36-23-28-19-7-3-6-18(22(34)35)20(19)33(23)12-14-8-10-15(11-9-14)16-4-1-2-5-17(16)21-29-31-32-30-21/h1-11H,12-13H2,(H,34,35)(H,29,30,31,32)
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n/an/a 580n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044384
PNG
(2-(2-Methoxy-ethyl)-3-[2'-(1H-tetrazol-5-yl)-biphe...)
Show SMILES COCCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H22N6O3/c1-34-14-13-22-26-21-8-4-7-20(25(32)33)23(21)31(22)15-16-9-11-17(12-10-16)18-5-2-3-6-19(18)24-27-29-30-28-24/h2-12H,13-15H2,1H3,(H,32,33)(H,27,28,29,30)
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n/an/a 580n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044395
PNG
(2-(2-Methylsulfanyl-ethyl)-3-[2'-(1H-tetrazol-5-yl...)
Show SMILES CSCCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H22N6O2S/c1-34-14-13-22-26-21-8-4-7-20(25(32)33)23(21)31(22)15-16-9-11-17(12-10-16)18-5-2-3-6-19(18)24-27-29-30-28-24/h2-12H,13-15H2,1H3,(H,32,33)(H,27,28,29,30)
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n/an/a 620n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044412
PNG
(2-Butylamino-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-y...)
Show SMILES CCCCNc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C26H25N7O2/c1-2-3-15-27-26-28-22-10-6-9-21(25(34)35)23(22)33(26)16-17-11-13-18(14-12-17)19-7-4-5-8-20(19)24-29-31-32-30-24/h4-14H,2-3,15-16H2,1H3,(H,27,28)(H,34,35)(H,29,30,31,32)
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n/an/a 650n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044399
PNG
(2-Methylaminomethyl-3-[2'-(1H-tetrazol-5-yl)-biphe...)
Show SMILES CNCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C24H21N7O2/c1-25-13-21-26-20-8-4-7-19(24(32)33)22(20)31(21)14-15-9-11-16(12-10-15)17-5-2-3-6-18(17)23-27-29-30-28-23/h2-12,25H,13-14H2,1H3,(H,32,33)(H,27,28,29,30)
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n/an/a 800n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044397
PNG
(2-Allyloxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylm...)
Show SMILES COC(=O)c1cccc2nc(OCC=C)n(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c12
Show InChI InChI=1S/C26H22N6O3/c1-3-15-35-26-27-22-10-6-9-21(25(33)34-2)23(22)32(26)16-17-11-13-18(14-12-17)19-7-4-5-8-20(19)24-28-30-31-29-24/h3-14H,1,15-16H2,2H3,(H,28,29,30,31)
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n/an/a 850n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044373
PNG
(2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Show SMILES CCOc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(O)=O
Show InChI InChI=1S/C24H20N6O3/c1-2-33-24-25-20-12-11-17(23(31)32)13-21(20)30(24)14-15-7-9-16(10-8-15)18-5-3-4-6-19(18)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)
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n/an/a 930n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044394
PNG
(2-Propoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylme...)
Show SMILES CCCOc1nc2cccc(C(=O)OCC)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C27H26N6O3/c1-3-16-36-27-28-23-11-7-10-22(26(34)35-4-2)24(23)33(27)17-18-12-14-19(15-13-18)20-8-5-6-9-21(20)25-29-31-32-30-25/h5-15H,3-4,16-17H2,1-2H3,(H,29,30,31,32)
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n/an/a 1.00E+3n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044383
PNG
(2-Butoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Show SMILES CCCCOc1nc2cccc(C(=O)OC)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C27H26N6O3/c1-3-4-16-36-27-28-23-11-7-10-22(26(34)35-2)24(23)33(27)17-18-12-14-19(15-13-18)20-8-5-6-9-21(20)25-29-31-32-30-25/h5-15H,3-4,16-17H2,1-2H3,(H,29,30,31,32)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044398
PNG
(3-[2'-(1H-Tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-(2...)
Show SMILES COC(=O)c1cccc2nc(OCC(F)(F)F)n(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c12
Show InChI InChI=1S/C25H19F3N6O3/c1-36-23(35)19-7-4-8-20-21(19)34(24(29-20)37-14-25(26,27)28)13-15-9-11-16(12-10-15)17-5-2-3-6-18(17)22-30-32-33-31-22/h2-12H,13-14H2,1H3,(H,30,31,32,33)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044380
PNG
(2-Morpholin-4-yl-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Show SMILES OC(=O)c1cccc2nc(N3CCOCC3)n(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c12
Show InChI InChI=1S/C26H23N7O3/c34-25(35)21-6-3-7-22-23(21)33(26(27-22)32-12-14-36-15-13-32)16-17-8-10-18(11-9-17)19-4-1-2-5-20(19)24-28-30-31-29-24/h1-11H,12-16H2,(H,34,35)(H,28,29,30,31)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044400
PNG
(2-Piperidin-1-yl-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Show SMILES OC(=O)c1cccc2nc(N3CCCCC3)n(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c12
Show InChI InChI=1S/C27H25N7O2/c35-26(36)22-9-6-10-23-24(22)34(27(28-23)33-15-4-1-5-16-33)17-18-11-13-19(14-12-18)20-7-2-3-8-21(20)25-29-31-32-30-25/h2-3,6-14H,1,4-5,15-17H2,(H,35,36)(H,29,30,31,32)
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Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044404
PNG
(2-(Ethyl-methyl-amino)-3-[2'-(1H-tetrazol-5-yl)-bi...)
Show SMILES CCN(C)c1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H23N7O2/c1-3-31(2)25-26-21-10-6-9-20(24(33)34)22(21)32(25)15-16-11-13-17(14-12-16)18-7-4-5-8-19(18)23-27-29-30-28-23/h4-14H,3,15H2,1-2H3,(H,33,34)(H,27,28,29,30)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044392
PNG
(2-Isobutyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylm...)
Show SMILES CC(C)Cc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C26H24N6O2/c1-16(2)14-23-27-22-9-5-8-21(26(33)34)24(22)32(23)15-17-10-12-18(13-11-17)19-6-3-4-7-20(19)25-28-30-31-29-25/h3-13,16H,14-15H2,1-2H3,(H,33,34)(H,28,29,30,31)
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n/an/a 3.20E+3n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044393
PNG
(2-sec-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl...)
Show SMILES CCC(C)c1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C26H24N6O2/c1-3-16(2)25-27-22-10-6-9-21(26(33)34)23(22)32(25)15-17-11-13-18(14-12-17)19-7-4-5-8-20(19)24-28-30-31-29-24/h4-14,16H,3,15H2,1-2H3,(H,33,34)(H,28,29,30,31)
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n/an/a 3.90E+3n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044385
PNG
(2-Ethoxy-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Show SMILES CCOc1nc2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(O)=O
Show InChI InChI=1S/C24H20N6O3/c1-2-33-24-25-20-13-17(23(31)32)11-12-21(20)30(24)14-15-7-9-16(10-8-15)18-5-3-4-6-19(18)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50044401
PNG
(2-Ethoxy-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Show SMILES CCOc1nc2c(cccc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(O)=O
Show InChI InChI=1S/C24H20N6O3/c1-2-33-24-25-21-19(23(31)32)8-5-9-20(21)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)
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n/an/a 4.50E+4n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortex

J Med Chem 36: 2182-95 (1993)


BindingDB Entry DOI: 10.7270/Q20Z73X8
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%