Affinity Data by PubMed id=8423593

PubMed code 8423593

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50003776 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description In vitro inhibition of thromboxane synthasase in microsomal platelet preparation				J Med Chem 36: 205-10 (1993) BindingDB Entry DOI: 10.7270/Q2XS5TFK
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50003797 (8-(4-Chloro-benzenesulfonylamino)-4-[2-(pyridin-3-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description In vitro inhibition of thromboxane synthasase in microsomal platelet preparation				J Med Chem 36: 205-10 (1993) BindingDB Entry DOI: 10.7270/Q2XS5TFK
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50046312 (8-(4-Chloro-benzenesulfonylamino)-4-[2-(pyridin-3-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description In vitro inhibition of thromboxane synthasase in microsomal platelet preparation				J Med Chem 36: 205-10 (1993) BindingDB Entry DOI: 10.7270/Q2XS5TFK
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50046311 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description In vitro inhibition of thromboxane synthasase in microsomal platelet preparation				J Med Chem 36: 205-10 (1993) BindingDB Entry DOI: 10.7270/Q2XS5TFK
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50046309 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description In vitro inhibition of thromboxane synthasase in microsomal platelet preparation				J Med Chem 36: 205-10 (1993) BindingDB Entry DOI: 10.7270/Q2XS5TFK
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50046310 (8-(4-Chloro-benzenesulfonylamino)-4-[2-(pyridin-3-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description In vitro inhibition of thromboxane synthasase in microsomal platelet preparation				J Med Chem 36: 205-10 (1993) BindingDB Entry DOI: 10.7270/Q2XS5TFK
CIBA-GEIGY Corporation Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%