Affinity Data by PubMed id=8426367

PubMed code 8426367

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lanosterol 14-alpha demethylase (Rattus norvegicus)	BDBM50046560 (17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition rat liver microsome cytochrome P450DM				J Med Chem 36: 410-6 (1993) BindingDB Entry DOI: 10.7270/Q2S181K5
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human))	BDBM50046561 (1-[17-(1,5-Dimethyl-hexyl)-3-hydroxy-4,4,10,13-tet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition of HMG-coA Reductase enzyme in chinese hamster ovary cells				J Med Chem 36: 410-6 (1993) BindingDB Entry DOI: 10.7270/Q2S181K5
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human))	BDBM50046560 (17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition of HMG-coA Reductase enzyme in chinese hamster ovary cells				J Med Chem 36: 410-6 (1993) BindingDB Entry DOI: 10.7270/Q2S181K5
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human))	BDBM50046560 (17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition of HMG-coA Reductase enzyme in chinese hamster ovary cells				J Med Chem 36: 410-6 (1993) BindingDB Entry DOI: 10.7270/Q2S181K5
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol 14-alpha demethylase (Rattus norvegicus)	BDBM50046560 (17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition rat liver microsome cytochrome P450DM				J Med Chem 36: 410-6 (1993) BindingDB Entry DOI: 10.7270/Q2S181K5
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol 14-alpha demethylase (Rattus norvegicus)	BDBM50046560 (17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition rat liver microsome cytochrome P450DM				J Med Chem 36: 410-6 (1993) BindingDB Entry DOI: 10.7270/Q2S181K5
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol 14-alpha demethylase (Rattus norvegicus)	BDBM50046561 (1-[17-(1,5-Dimethyl-hexyl)-3-hydroxy-4,4,10,13-tet...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition rat liver microsome cytochrome P450DM				J Med Chem 36: 410-6 (1993) BindingDB Entry DOI: 10.7270/Q2S181K5
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol 14-alpha demethylase (Rattus norvegicus)	BDBM50046561 (1-[17-(1,5-Dimethyl-hexyl)-3-hydroxy-4,4,10,13-tet...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition rat liver microsome cytochrome P450DM				J Med Chem 36: 410-6 (1993) BindingDB Entry DOI: 10.7270/Q2S181K5
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human))	BDBM50046561 (1-[17-(1,5-Dimethyl-hexyl)-3-hydroxy-4,4,10,13-tet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition of HMG-coA Reductase enzyme in AR45 cells				J Med Chem 36: 410-6 (1993) BindingDB Entry DOI: 10.7270/Q2S181K5
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human))	BDBM50046560 (17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition of HMG-coA Reductase enzyme in AR45 cells				J Med Chem 36: 410-6 (1993) BindingDB Entry DOI: 10.7270/Q2S181K5
Institute Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%