Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50056445 (1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroerg...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1A receptor in piglet hippocampus using [3H]8-OH-DPAT | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM21392 (3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1D receptor was determined | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Sus scrofa) | BDBM50005835 ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1D receptor in piglet caudate using [3H]5-HT | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1C receptor was determined | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat)) | BDBM21392 (3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1C receptor was determined | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM50005835 ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 2 receptor in rat cortex using [3H]- ketanserin | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM50056445 (1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroerg...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | >5.01E+3 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 2 receptor in rat cortex using [3H]- ketanserin | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Homo sapiens (Human)) | BDBM21392 (3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 2 receptor was determined | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50005835 ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1C receptor in piglet choroid plexus using [3H]5-HT | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1A receptor was determined | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Serotonin 2 (5-HT2) receptor (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 2 receptor was determined | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50005835 ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1A receptor in piglet hippocampus using [3H]8-OH-DPAT | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Sus scrofa) | BDBM50056445 (1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroerg...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1D receptor in piglet caudate using [3H]5-HT | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50056445 (1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroerg...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | 5.01E+4 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1C receptor in piglet choroid plexus using [3H]5-HT | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM21392 (3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.316 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1A receptor was determined | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1D receptor was determined | J Med Chem 36: 1918-9 (1993) Article DOI: 10.1021/jm00065a015 BindingDB Entry DOI: 10.7270/Q2JS9SNZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |