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PubMed code 9207949

Compile data set for download or QSAR
Found 26 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058928
PNG
(CHEMBL292795 | [6-(4-Carbamimidoyl-phenylcarbamoyl...)
Show SMILES NC(=N)c1ccc(NC(=O)c2ccc3C(=O)N(CC(O)=O)CCc3c2)cc1
Show InChI InChI=1S/C19H18N4O4/c20-17(21)11-1-4-14(5-2-11)22-18(26)13-3-6-15-12(9-13)7-8-23(19(15)27)10-16(24)25/h1-6,9H,7-8,10H2,(H3,20,21)(H,22,26)(H,24,25)
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n/an/a 3n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058924
PNG
(CHEMBL68183 | [6-(4-Carbamimidoyl-phenylethynyl)-1...)
Show SMILES NC(=N)c1ccc(cc1)C#Cc1ccc2C(=O)N(CC(O)=O)CCc2c1
Show InChI InChI=1S/C20H17N3O3/c21-19(22)15-6-3-13(4-7-15)1-2-14-5-8-17-16(11-14)9-10-23(20(17)26)12-18(24)25/h3-8,11H,9-10,12H2,(H3,21,22)(H,24,25)
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n/an/a 33n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058908
PNG
(CHEMBL67520 | {6-[(E)-2-(4-Carbamimidoyl-phenyl)-v...)
Show SMILES NC(=N)c1ccc(\C=C\c2ccc3C(=O)N(CC(O)=O)CCc3c2)cc1
Show InChI InChI=1S/C20H19N3O3/c21-19(22)15-6-3-13(4-7-15)1-2-14-5-8-17-16(11-14)9-10-23(20(17)26)12-18(24)25/h1-8,11H,9-10,12H2,(H3,21,22)(H,24,25)/b2-1+
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n/an/a 48n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058914
PNG
(CHEMBL303597 | [6-(4-Carbamimidoyl-benzoylamino)-1...)
Show SMILES NC(=N)c1ccc(cc1)C(=O)Nc1ccc2C(=O)N(CC(O)=O)CCc2c1
Show InChI InChI=1S/C19H18N4O4/c20-17(21)11-1-3-12(4-2-11)18(26)22-14-5-6-15-13(9-14)7-8-23(19(15)27)10-16(24)25/h1-6,9H,7-8,10H2,(H3,20,21)(H,22,26)(H,24,25)
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n/an/a 76n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058920
PNG
(CHEMBL66669 | {6-[2-(4-Carbamimidoyl-phenyl)-ethyl...)
Show SMILES NC(=N)c1ccc(CCc2ccc3C(=O)N(CC(O)=O)CCc3c2)cc1
Show InChI InChI=1S/C20H21N3O3/c21-19(22)15-6-3-13(4-7-15)1-2-14-5-8-17-16(11-14)9-10-23(20(17)26)12-18(24)25/h3-8,11H,1-2,9-10,12H2,(H3,21,22)(H,24,25)
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n/an/a 110n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058910
PNG
(CHEMBL63770 | {6-[(Z)-2-(4-Carbamimidoyl-phenyl)-v...)
Show SMILES NC(=N)c1ccc(\C=C/c2ccc3C(=O)N(CC(O)=O)CCc3c2)cc1
Show InChI InChI=1S/C20H19N3O3/c21-19(22)15-6-3-13(4-7-15)1-2-14-5-8-17-16(11-14)9-10-23(20(17)26)12-18(24)25/h1-8,11H,9-10,12H2,(H3,21,22)(H,24,25)/b2-1-
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n/an/a 290n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058911
PNG
(CHEMBL63887 | [6-(4-Carbamimidoyl-benzyloxy)-1-oxo...)
Show SMILES NC(=N)c1ccc(COc2ccc3C(=O)N(CC(O)=O)CCc3c2)cc1
Show InChI InChI=1S/C19H19N3O4/c20-18(21)13-3-1-12(2-4-13)11-26-15-5-6-16-14(9-15)7-8-22(19(16)25)10-17(23)24/h1-6,9H,7-8,10-11H2,(H3,20,21)(H,23,24)
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n/an/a 600n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058907
PNG
(CHEMBL67294 | [1-Oxo-6-(4-piperidin-4-yl-butoxy)-3...)
Show SMILES OC(=O)CN1CCc2cc(OCCCCC3CCNCC3)ccc2C1=O
Show InChI InChI=1S/C20H28N2O4/c23-19(24)14-22-11-8-16-13-17(4-5-18(16)20(22)25)26-12-2-1-3-15-6-9-21-10-7-15/h4-5,13,15,21H,1-3,6-12,14H2,(H,23,24)
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n/an/a 1.80E+3n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058916
PNG
(CHEMBL63740 | [6-(4-Guanidinomethyl-benzyloxy)-1-o...)
Show SMILES NC(=N)NCc1ccc(COc2ccc3C(=O)N(CC(O)=O)CCc3c2)cc1
Show InChI InChI=1S/C20H22N4O4/c21-20(22)23-10-13-1-3-14(4-2-13)12-28-16-5-6-17-15(9-16)7-8-24(19(17)27)11-18(25)26/h1-6,9H,7-8,10-12H2,(H,25,26)(H4,21,22,23)
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n/an/a 4.00E+3n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058930
PNG
(CHEMBL292994 | [7-(4-Carbamimidoyl-benzyloxy)-1-ox...)
Show SMILES NC(=N)c1ccc(COc2ccc3CCN(CC(O)=O)C(=O)c3c2)cc1
Show InChI InChI=1S/C19H19N3O4/c20-18(21)14-3-1-12(2-4-14)11-26-15-6-5-13-7-8-22(10-17(23)24)19(25)16(13)9-15/h1-6,9H,7-8,10-11H2,(H3,20,21)(H,23,24)
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n/an/a 4.00E+3n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058923
PNG
(CHEMBL67351 | [1-Oxo-6-(3-piperidin-4-yl-propoxy)-...)
Show SMILES OC(=O)CN1CCc2cc(OCCCC3CCNCC3)ccc2C1=O
Show InChI InChI=1S/C19H26N2O4/c22-18(23)13-21-10-7-15-12-16(3-4-17(15)19(21)24)25-11-1-2-14-5-8-20-9-6-14/h3-4,12,14,20H,1-2,5-11,13H2,(H,22,23)
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n/an/a 6.00E+3n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058913
PNG
(CHEMBL65285 | {6-[2-(4-Carbamimidoyl-phenyl)-ethox...)
Show SMILES NC(=N)c1ccc(CCOc2ccc3C(=O)N(CC(O)=O)CCc3c2)cc1
Show InChI InChI=1S/C20H21N3O4/c21-19(22)14-3-1-13(2-4-14)8-10-27-16-5-6-17-15(11-16)7-9-23(20(17)26)12-18(24)25/h1-6,11H,7-10,12H2,(H3,21,22)(H,24,25)
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n/an/a 6.00E+3n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058926
PNG
(CHEMBL63643 | [6-(5-Guanidino-pentyloxy)-1-oxo-3,4...)
Show SMILES NC(=N)NCCCCCOc1ccc2C(=O)N(CC(O)=O)CCc2c1
Show InChI InChI=1S/C17H24N4O4/c18-17(19)20-7-2-1-3-9-25-13-4-5-14-12(10-13)6-8-21(16(14)24)11-15(22)23/h4-5,10H,1-3,6-9,11H2,(H,22,23)(H4,18,19,20)
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n/an/a 9.00E+3n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058931
PNG
(CHEMBL63817 | [6-(4-Guanidino-butoxy)-1-oxo-3,4-di...)
Show SMILES NC(=N)NCCCCOc1ccc2C(=O)N(CC(O)=O)CCc2c1
Show InChI InChI=1S/C16H22N4O4/c17-16(18)19-6-1-2-8-24-12-3-4-13-11(9-12)5-7-20(15(13)23)10-14(21)22/h3-4,9H,1-2,5-8,10H2,(H,21,22)(H4,17,18,19)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058917
PNG
(CHEMBL413769 | [1-Oxo-6-(2-piperidin-4-yl-ethoxy)-...)
Show SMILES OC(=O)CN1CCc2cc(OCCC3CCNCC3)ccc2C1=O
Show InChI InChI=1S/C18H24N2O4/c21-17(22)12-20-9-5-14-11-15(1-2-16(14)18(20)23)24-10-6-13-3-7-19-8-4-13/h1-2,11,13,19H,3-10,12H2,(H,21,22)
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n/an/a 1.10E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058909
PNG
(CHEMBL65200 | [6-(6-Guanidino-hexyloxy)-1-oxo-3,4-...)
Show SMILES NC(=N)NCCCCCCOc1ccc2C(=O)N(CC(O)=O)CCc2c1
Show InChI InChI=1S/C18H26N4O4/c19-18(20)21-8-3-1-2-4-10-26-14-5-6-15-13(11-14)7-9-22(17(15)25)12-16(23)24/h5-6,11H,1-4,7-10,12H2,(H,23,24)(H4,19,20,21)
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n/an/a 1.20E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058925
PNG
(CHEMBL63899 | [6-(4-Aminomethyl-benzyloxy)-1-oxo-3...)
Show SMILES NCc1ccc(COc2ccc3C(=O)N(CC(O)=O)CCc3c2)cc1
Show InChI InChI=1S/C19H20N2O4/c20-10-13-1-3-14(4-2-13)12-25-16-5-6-17-15(9-16)7-8-21(19(17)24)11-18(22)23/h1-6,9H,7-8,10-12,20H2,(H,22,23)
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n/an/a 1.20E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058918
PNG
(CHEMBL303319 | [6-(3-Guanidinomethyl-benzyloxy)-1-...)
Show SMILES NC(=N)NCc1cccc(COc2ccc3C(=O)N(CC(O)=O)CCc3c2)c1
Show InChI InChI=1S/C20H22N4O4/c21-20(22)23-10-13-2-1-3-14(8-13)12-28-16-4-5-17-15(9-16)6-7-24(19(17)27)11-18(25)26/h1-5,8-9H,6-7,10-12H2,(H,25,26)(H4,21,22,23)
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n/an/a 1.40E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058929
PNG
(CHEMBL63666 | [6-(4-Amino-butoxy)-1-oxo-3,4-dihydr...)
Show SMILES NCCCCOc1ccc2C(=O)N(CC(O)=O)CCc2c1
Show InChI InChI=1S/C15H20N2O4/c16-6-1-2-8-21-12-3-4-13-11(9-12)5-7-17(15(13)20)10-14(18)19/h3-4,9H,1-2,5-8,10,16H2,(H,18,19)
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n/an/a 1.80E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058921
PNG
(CHEMBL63884 | [6-(6-Amino-hexyloxy)-1-oxo-3,4-dihy...)
Show SMILES NCCCCCCOc1ccc2C(=O)N(CC(O)=O)CCc2c1
Show InChI InChI=1S/C17H24N2O4/c18-8-3-1-2-4-10-23-14-5-6-15-13(11-14)7-9-19(17(15)22)12-16(20)21/h5-6,11H,1-4,7-10,12,18H2,(H,20,21)
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n/an/a 1.90E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058932
PNG
(CHEMBL63843 | [6-(5-Amino-pentyloxy)-1-oxo-3,4-dih...)
Show SMILES NCCCCCOc1ccc2C(=O)N(CC(O)=O)CCc2c1
Show InChI InChI=1S/C16H22N2O4/c17-7-2-1-3-9-22-13-4-5-14-12(10-13)6-8-18(16(14)21)11-15(19)20/h4-5,10H,1-3,6-9,11,17H2,(H,19,20)
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n/an/a 2.80E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058915
PNG
(CHEMBL293838 | [6-(3-Guanidino-propoxy)-1-oxo-3,4-...)
Show SMILES NC(=N)NCCCOc1ccc2C(=O)N(CC(O)=O)CCc2c1
Show InChI InChI=1S/C15H20N4O4/c16-15(17)18-5-1-7-23-11-2-3-12-10(8-11)4-6-19(14(12)22)9-13(20)21/h2-3,8H,1,4-7,9H2,(H,20,21)(H4,16,17,18)
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n/an/a 4.40E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058927
PNG
(CHEMBL63478 | [7-(4-Guanidino-butoxy)-1-oxo-3,4-di...)
Show SMILES NC(=N)NCCCCOc1ccc2CCN(CC(O)=O)C(=O)c2c1
Show InChI InChI=1S/C16H22N4O4/c17-16(18)19-6-1-2-8-24-12-4-3-11-5-7-20(10-14(21)22)15(23)13(11)9-12/h3-4,9H,1-2,5-8,10H2,(H,21,22)(H4,17,18,19)
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n/an/a 4.60E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058912
PNG
(CHEMBL63187 | [6-(3-Amino-propoxy)-1-oxo-3,4-dihyd...)
Show SMILES NCCCOc1ccc2C(=O)N(CC(O)=O)CCc2c1
Show InChI InChI=1S/C14H18N2O4/c15-5-1-7-20-11-2-3-12-10(8-11)4-6-16(14(12)19)9-13(17)18/h2-3,8H,1,4-7,9,15H2,(H,17,18)
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n/an/a 4.80E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058919
PNG
(CHEMBL302177 | [1-Oxo-6-(piperidin-4-ylmethoxy)-3,...)
Show SMILES OC(=O)CN1CCc2cc(OCC3CCNCC3)ccc2C1=O
Show InChI InChI=1S/C17H22N2O4/c20-16(21)10-19-8-5-13-9-14(1-2-15(13)17(19)22)23-11-12-3-6-18-7-4-12/h1-2,9,12,18H,3-8,10-11H2,(H,20,21)
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n/an/a 5.50E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50058922
PNG
(CHEMBL68001 | [6-(3-Aminomethyl-benzyloxy)-1-oxo-3...)
Show SMILES NCc1cccc(COc2ccc3C(=O)N(CC(O)=O)CCc3c2)c1
Show InChI InChI=1S/C19H20N2O4/c20-10-13-2-1-3-14(8-13)12-25-16-4-5-17-15(9-16)6-7-21(19(17)24)11-18(22)23/h1-5,8-9H,6-7,10-12,20H2,(H,22,23)
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n/an/a 7.70E+4n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISA

J Med Chem 40: 2085-101 (1997)


Article DOI: 10.1021/jm9701076
BindingDB Entry DOI: 10.7270/Q23T9GBH
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%