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PubMed code 9276015

Compile data set for download or QSAR
Found 41 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059542
PNG
(1-(2-(4-carboxyphenoxy)ethyl)-3-dodecanoyl-1H-indo...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(CCOc2ccc(cc2)C(O)=O)c2ccccc12
Show InChI InChI=1S/C30H37NO6/c1-2-3-4-5-6-7-8-9-10-15-26(32)27-24-13-11-12-14-25(24)31(28(27)30(35)36)20-21-37-23-18-16-22(17-19-23)29(33)34/h11-14,16-19H,2-10,15,20-21H2,1H3,(H,33,34)(H,35,36)
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n/an/a 500n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059525
PNG
(1-(10-Carboxy-decyl)-3-dodecanoyl-1H-indole-2-carb...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(CCCCCCCCCCC(O)=O)c2ccccc12
Show InChI InChI=1S/C32H49NO5/c1-2-3-4-5-6-7-10-13-16-23-28(34)30-26-21-18-19-22-27(26)33(31(30)32(37)38)25-20-15-12-9-8-11-14-17-24-29(35)36/h18-19,21-22H,2-17,20,23-25H2,1H3,(H,35,36)(H,37,38)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059545
PNG
(1-(7-Carboxy-heptyl)-3-octadecanoyl-1H-indole-2-ca...)
Show SMILES CCCCCCCCCCCCCCCCCC(=O)c1c(C(O)=O)n(CCCCCCCC(O)=O)c2ccccc12
Show InChI InChI=1S/C35H55NO5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-26-31(37)33-29-24-21-22-25-30(29)36(34(33)35(40)41)28-23-18-15-17-20-27-32(38)39/h21-22,24-25H,2-20,23,26-28H2,1H3,(H,38,39)(H,40,41)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059550
PNG
(1-(7-Carboxy-heptyl)-3-dodecanoyl-1H-indole-2-carb...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(CCCCCCCC(O)=O)c2ccccc12
Show InChI InChI=1S/C29H43NO5/c1-2-3-4-5-6-7-8-10-13-20-25(31)27-23-18-15-16-19-24(23)30(28(27)29(34)35)22-17-12-9-11-14-21-26(32)33/h15-16,18-19H,2-14,17,20-22H2,1H3,(H,32,33)(H,34,35)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059531
PNG
(1-(8-Carboxy-octyl)-3-dodecanoyl-1H-indole-2-carbo...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(CCCCCCCCC(O)=O)c2ccccc12
Show InChI InChI=1S/C30H45NO5/c1-2-3-4-5-6-7-8-11-14-21-26(32)28-24-19-16-17-20-25(24)31(29(28)30(35)36)23-18-13-10-9-12-15-22-27(33)34/h16-17,19-20H,2-15,18,21-23H2,1H3,(H,33,34)(H,35,36)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059543
PNG
(1-[2-(4-Carboxymethyl-phenoxy)-ethyl]-3-dodecanoyl...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(CCOc2ccc(CC(O)=O)cc2)c2ccccc12
Show InChI InChI=1S/C31H39NO6/c1-2-3-4-5-6-7-8-9-10-15-27(33)29-25-13-11-12-14-26(25)32(30(29)31(36)37)20-21-38-24-18-16-23(17-19-24)22-28(34)35/h11-14,16-19H,2-10,15,20-22H2,1H3,(H,34,35)(H,36,37)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059520
PNG
(1-[2-(3-Carboxymethyl-phenoxy)-ethyl]-3-dodecanoyl...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(CCOc2cccc(CC(O)=O)c2)c2ccccc12
Show InChI InChI=1S/C31H39NO6/c1-2-3-4-5-6-7-8-9-10-18-27(33)29-25-16-11-12-17-26(25)32(30(29)31(36)37)19-20-38-24-15-13-14-23(21-24)22-28(34)35/h11-17,21H,2-10,18-20,22H2,1H3,(H,34,35)(H,36,37)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059535
PNG
(1-[2-(3-Carboxy-phenoxy)-ethyl]-3-dodecanoyl-1H-in...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(CCOc2cccc(c2)C(O)=O)c2ccccc12
Show InChI InChI=1S/C30H37NO6/c1-2-3-4-5-6-7-8-9-10-18-26(32)27-24-16-11-12-17-25(24)31(28(27)30(35)36)19-20-37-23-15-13-14-22(21-23)29(33)34/h11-17,21H,2-10,18-20H2,1H3,(H,33,34)(H,35,36)
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n/an/a 1.90E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059538
PNG
(1-(6-Carboxy-hexyl)-3-dodecanoyl-1H-indole-2-carbo...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(CCCCCCC(O)=O)c2ccccc12
Show InChI InChI=1S/C28H41NO5/c1-2-3-4-5-6-7-8-9-12-19-24(30)26-22-17-14-15-18-23(22)29(27(26)28(33)34)21-16-11-10-13-20-25(31)32/h14-15,17-18H,2-13,16,19-21H2,1H3,(H,31,32)(H,33,34)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059521
PNG
(1-[4-(2-Carboxy-ethyl)-benzyl]-3-dodecanoyl-1H-ind...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(Cc2ccc(CCC(O)=O)cc2)c2ccccc12
Show InChI InChI=1S/C31H39NO5/c1-2-3-4-5-6-7-8-9-10-15-27(33)29-25-13-11-12-14-26(25)32(30(29)31(36)37)22-24-18-16-23(17-19-24)20-21-28(34)35/h11-14,16-19H,2-10,15,20-22H2,1H3,(H,34,35)(H,36,37)
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n/an/a 4.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059548
PNG
(1-[4-((E)-2-Carboxy-vinyl)-benzyl]-3-dodecanoyl-1H...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(Cc2ccc(C=CC(O)=O)cc2)c2ccccc12 |w:25.25|
Show InChI InChI=1S/C31H37NO5/c1-2-3-4-5-6-7-8-9-10-15-27(33)29-25-13-11-12-14-26(25)32(30(29)31(36)37)22-24-18-16-23(17-19-24)20-21-28(34)35/h11-14,16-21H,2-10,15,22H2,1H3,(H,34,35)(H,36,37)
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n/an/a 4.10E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059528
PNG
(1-[3-(2-Carboxy-ethyl)-benzyl]-3-dodecanoyl-1H-ind...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(Cc2cccc(CCC(O)=O)c2)c2ccccc12
Show InChI InChI=1S/C31H39NO5/c1-2-3-4-5-6-7-8-9-10-18-27(33)29-25-16-11-12-17-26(25)32(30(29)31(36)37)22-24-15-13-14-23(21-24)19-20-28(34)35/h11-17,21H,2-10,18-20,22H2,1H3,(H,34,35)(H,36,37)
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n/an/a 4.30E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059540
PNG
(1-[3-((E)-2-Carboxy-vinyl)-benzyl]-3-dodecanoyl-1H...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(Cc2cccc(C=CC(O)=O)c2)c2ccccc12 |w:26.26|
Show InChI InChI=1S/C31H37NO5/c1-2-3-4-5-6-7-8-9-10-18-27(33)29-25-16-11-12-17-26(25)32(30(29)31(36)37)22-24-15-13-14-23(21-24)19-20-28(34)35/h11-17,19-21H,2-10,18,22H2,1H3,(H,34,35)(H,36,37)
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n/an/a 5.30E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059541
PNG
(3-(4-Dodecyloxy-benzoyl)-1-methyl-1H-indole-2-carb...)
Show SMILES CCCCCCCCCCCCOc1ccc(cc1)C(=O)c1c(C(O)=O)n(C)c2ccccc12
Show InChI InChI=1S/C29H37NO4/c1-3-4-5-6-7-8-9-10-11-14-21-34-23-19-17-22(18-20-23)28(31)26-24-15-12-13-16-25(24)30(2)27(26)29(32)33/h12-13,15-20H,3-11,14,21H2,1-2H3,(H,32,33)
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n/an/a 7.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059518
PNG
(3-[2-(2-Decyloxy-phenyl)-acetyl]-1-methyl-1H-indol...)
Show SMILES CCCCCCCCCCOc1ccccc1CC(=O)c1c(C(O)=O)n(C)c2ccccc12
Show InChI InChI=1S/C28H35NO4/c1-3-4-5-6-7-8-9-14-19-33-25-18-13-10-15-21(25)20-24(30)26-22-16-11-12-17-23(22)29(2)27(26)28(31)32/h10-13,15-18H,3-9,14,19-20H2,1-2H3,(H,31,32)
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n/an/a 7.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059514
PNG
(3-[2-(4-Decyloxy-phenyl)-acetyl]-1-methyl-1H-indol...)
Show SMILES CCCCCCCCCCOc1ccc(CC(=O)c2c(C(O)=O)n(C)c3ccccc23)cc1
Show InChI InChI=1S/C28H35NO4/c1-3-4-5-6-7-8-9-12-19-33-22-17-15-21(16-18-22)20-25(30)26-23-13-10-11-14-24(23)29(2)27(26)28(31)32/h10-11,13-18H,3-9,12,19-20H2,1-2H3,(H,31,32)
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n/an/a 7.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059530
PNG
(3-(3-Dodecyloxy-benzoyl)-1-methyl-1H-indole-2-carb...)
Show SMILES CCCCCCCCCCCCOc1cccc(c1)C(=O)c1c(C(O)=O)n(C)c2ccccc12
Show InChI InChI=1S/C29H37NO4/c1-3-4-5-6-7-8-9-10-11-14-20-34-23-17-15-16-22(21-23)28(31)26-24-18-12-13-19-25(24)30(2)27(26)29(32)33/h12-13,15-19,21H,3-11,14,20H2,1-2H3,(H,32,33)
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n/an/a 7.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059533
PNG
(1-Methyl-3-tetradecanoyl-1H-indole-2-carboxylic ac...)
Show SMILES CCCCCCCCCCCCCC(=O)c1c(C(O)=O)n(C)c2ccccc12
Show InChI InChI=1S/C24H35NO3/c1-3-4-5-6-7-8-9-10-11-12-13-18-21(26)22-19-16-14-15-17-20(19)25(2)23(22)24(27)28/h14-17H,3-13,18H2,1-2H3,(H,27,28)
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n/an/a 8.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059532
PNG
(1-(5-Carboxy-pentyl)-3-dodecanoyl-1H-indole-2-carb...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(CCCCCC(O)=O)c2ccccc12
Show InChI InChI=1S/C27H39NO5/c1-2-3-4-5-6-7-8-9-11-18-23(29)25-21-16-13-14-17-22(21)28(26(25)27(32)33)20-15-10-12-19-24(30)31/h13-14,16-17H,2-12,15,18-20H2,1H3,(H,30,31)(H,32,33)
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n/an/a 8.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059534
PNG
(3-Dodecanoyl-1-methyl-1H-indole-2-carboxylic acid ...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(C)c2ccccc12
Show InChI InChI=1S/C22H31NO3/c1-3-4-5-6-7-8-9-10-11-16-19(24)20-17-14-12-13-15-18(17)23(2)21(20)22(25)26/h12-15H,3-11,16H2,1-2H3,(H,25,26)
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n/an/a 8.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059524
PNG
(5-Chloro-3-dodecanoyl-1-methyl-1H-indole-2-carboxy...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(C)c2ccc(Cl)cc12
Show InChI InChI=1S/C22H30ClNO3/c1-3-4-5-6-7-8-9-10-11-12-19(25)20-17-15-16(23)13-14-18(17)24(2)21(20)22(26)27/h13-15H,3-12H2,1-2H3,(H,26,27)
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n/an/a 8.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059537
PNG
(3-Dodecanoyl-5-methoxy-1-methyl-1H-indole-2-carbox...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(C)c2ccc(OC)cc12
Show InChI InChI=1S/C23H33NO4/c1-4-5-6-7-8-9-10-11-12-13-20(25)21-18-16-17(28-3)14-15-19(18)24(2)22(21)23(26)27/h14-16H,4-13H2,1-3H3,(H,26,27)
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n/an/a 8.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059522
PNG
(1-Methyl-3-octadecanoyl-1H-indole-2-carboxylic aci...)
Show SMILES CCCCCCCCCCCCCCCCCC(=O)c1c(C(O)=O)n(C)c2ccccc12
Show InChI InChI=1S/C28H43NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22-25(30)26-23-20-18-19-21-24(23)29(2)27(26)28(31)32/h18-21H,3-17,22H2,1-2H3,(H,31,32)
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n/an/a 8.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059546
PNG
(1-Hexyl-3-octadecanoyl-1H-indole-2-carboxylic acid...)
Show SMILES CCCCCCCCCCCCCCCCCC(=O)c1c(C(O)=O)n(CCCCCC)c2ccccc12
Show InChI InChI=1S/C33H53NO3/c1-3-5-7-9-10-11-12-13-14-15-16-17-18-19-20-26-30(35)31-28-24-21-22-25-29(28)34(32(31)33(36)37)27-23-8-6-4-2/h21-22,24-25H,3-20,23,26-27H2,1-2H3,(H,36,37)
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n/an/a 9.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059551
PNG
(6-Chloro-3-dodecanoyl-1-methyl-1H-indole-2-carboxy...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(C)c2cc(Cl)ccc12
Show InChI InChI=1S/C22H30ClNO3/c1-3-4-5-6-7-8-9-10-11-12-19(25)20-17-14-13-16(23)15-18(17)24(2)21(20)22(26)27/h13-15H,3-12H2,1-2H3,(H,26,27)
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n/an/a 9.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059516
PNG
(4-Chloro-3-dodecanoyl-1-methyl-1H-indole-2-carboxy...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(C)c2cccc(Cl)c12
Show InChI InChI=1S/C22H30ClNO3/c1-3-4-5-6-7-8-9-10-11-15-18(25)20-19-16(23)13-12-14-17(19)24(2)21(20)22(26)27/h12-14H,3-11,15H2,1-2H3,(H,26,27)
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n/an/a 9.00E+3n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059553
PNG
(3-[3-(4-Decyloxy-phenyl)-propionyl]-1-methyl-1H-in...)
Show SMILES CCCCCCCCCCOc1ccc(CCC(=O)c2c(C(O)=O)n(C)c3ccccc23)cc1
Show InChI InChI=1S/C29H37NO4/c1-3-4-5-6-7-8-9-12-21-34-23-18-15-22(16-19-23)17-20-26(31)27-24-13-10-11-14-25(24)30(2)28(27)29(32)33/h10-11,13-16,18-19H,3-9,12,17,20-21H2,1-2H3,(H,32,33)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059519
PNG
(3-Dodecanoyl-1-methyl-5-nitro-1H-indole-2-carboxyl...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(C)c2ccc(cc12)[N+]([O-])=O
Show InChI InChI=1S/C22H30N2O5/c1-3-4-5-6-7-8-9-10-11-12-19(25)20-17-15-16(24(28)29)13-14-18(17)23(2)21(20)22(26)27/h13-15H,3-12H2,1-2H3,(H,26,27)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059549
PNG
(3-[2-(3-Decyloxy-phenyl)-acetyl]-1-methyl-1H-indol...)
Show SMILES CCCCCCCCCCOc1cccc(CC(=O)c2c(C(O)=O)n(C)c3ccccc23)c1
Show InChI InChI=1S/C28H35NO4/c1-3-4-5-6-7-8-9-12-18-33-22-15-13-14-21(19-22)20-25(30)26-23-16-10-11-17-24(23)29(2)27(26)28(31)32/h10-11,13-17,19H,3-9,12,18,20H2,1-2H3,(H,31,32)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059552
PNG
(3-Dodecanoyl-5-hydroxy-1-methyl-1H-indole-2-carbox...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(C)c2ccc(O)cc12
Show InChI InChI=1S/C22H31NO4/c1-3-4-5-6-7-8-9-10-11-12-19(25)20-17-15-16(24)13-14-18(17)23(2)21(20)22(26)27/h13-15,24H,3-12H2,1-2H3,(H,26,27)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059526
PNG
(1-Heptyl-3-octadecanoyl-1H-indole-2-carboxylic aci...)
Show SMILES CCCCCCCCCCCCCCCCCC(=O)c1c(C(O)=O)n(CCCCCCC)c2ccccc12
Show InChI InChI=1S/C34H55NO3/c1-3-5-7-9-10-11-12-13-14-15-16-17-18-19-21-27-31(36)32-29-25-22-23-26-30(29)35(33(32)34(37)38)28-24-20-8-6-4-2/h22-23,25-26H,3-21,24,27-28H2,1-2H3,(H,37,38)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059517
PNG
(3-[3-(3-Decyloxy-phenyl)-propionyl]-1-methyl-1H-in...)
Show SMILES CCCCCCCCCCOc1cccc(CCC(=O)c2c(C(O)=O)n(C)c3ccccc23)c1
Show InChI InChI=1S/C29H37NO4/c1-3-4-5-6-7-8-9-12-20-34-23-15-13-14-22(21-23)18-19-26(31)27-24-16-10-11-17-25(24)30(2)28(27)29(32)33/h10-11,13-17,21H,3-9,12,18-20H2,1-2H3,(H,32,33)
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n/an/a 1.10E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059523
PNG
((6Z,9Z,12Z,15Z)-1,1,1-trifluorohenicosa-6,9,12,15-...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)C(F)(F)F
Show InChI InChI=1S/C21H31F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(25)21(22,23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3/b7-6-,10-9-,13-12-,16-15-
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n/an/a 1.10E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059547
PNG
(3-Dodecanoyl-1,4,5-trimethyl-1H-pyrrole-2-carboxyl...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C)c(C)n(C)c1C(O)=O
Show InChI InChI=1S/C20H33NO3/c1-5-6-7-8-9-10-11-12-13-14-17(22)18-15(2)16(3)21(4)19(18)20(23)24/h5-14H2,1-4H3,(H,23,24)
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n/an/a 1.10E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059539
PNG
(3-Dodecanoyl-5-fluoro-1-methyl-1H-indole-2-carboxy...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(C)c2ccc(F)cc12
Show InChI InChI=1S/C22H30FNO3/c1-3-4-5-6-7-8-9-10-11-12-19(25)20-17-15-16(23)13-14-18(17)24(2)21(20)22(26)27/h13-15H,3-12H2,1-2H3,(H,26,27)
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n/an/a 1.10E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059536
PNG
(CHEMBL90088 | Pyrrolidine-2-carboxylic acid hexade...)
Show SMILES CCCCCCCCCCCCCCCCNC(=O)C1CCCN1
Show InChI InChI=1S/C21H42N2O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18-23-21(24)20-17-16-19-22-20/h20,22H,2-19H2,1H3,(H,23,24)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059544
PNG
(3-Decanoyl-1-methyl-1H-indole-2-carboxylic acid | ...)
Show SMILES CCCCCCCCCC(=O)c1c(C(O)=O)n(C)c2ccccc12
Show InChI InChI=1S/C20H27NO3/c1-3-4-5-6-7-8-9-14-17(22)18-15-12-10-11-13-16(15)21(2)19(18)20(23)24/h10-13H,3-9,14H2,1-2H3,(H,23,24)
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n/an/a 1.80E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059515
PNG
((1-Methyl-3-octadecanoyl-1H-indol-2-yl)-acetic aci...)
Show SMILES CCCCCCCCCCCCCCCCCC(=O)c1c(CC(O)=O)n(C)c2ccccc12
Show InChI InChI=1S/C29H45NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22-27(31)29-24-20-18-19-21-25(24)30(2)26(29)23-28(32)33/h18-21H,3-17,22-23H2,1-2H3,(H,32,33)
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n/an/a>3.30E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059513
PNG
(1-Methyl-3-octanoyl-1H-indole-2-carboxylic acid | ...)
Show SMILES CCCCCCCC(=O)c1c(C(O)=O)n(C)c2ccccc12
Show InChI InChI=1S/C18H23NO3/c1-3-4-5-6-7-12-15(20)16-13-10-8-9-11-14(13)19(2)17(16)18(21)22/h8-11H,3-7,12H2,1-2H3,(H,21,22)
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n/an/a>3.30E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059527
PNG
(1-Carboxymethyl-3-dodecanoyl-1H-indole-2-carboxyli...)
Show SMILES CCCCCCCCCCCC(=O)c1c(C(O)=O)n(CC(O)=O)c2ccccc12
Show InChI InChI=1S/C23H31NO5/c1-2-3-4-5-6-7-8-9-10-15-19(25)21-17-13-11-12-14-18(17)24(16-20(26)27)22(21)23(28)29/h11-14H,2-10,15-16H2,1H3,(H,26,27)(H,28,29)
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n/an/a>3.30E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
Cytosolic phospholipase A2


(Bos taurus)		BDBM50059529
PNG
(3-[3-(2-Decyloxy-phenyl)-propionyl]-1-methyl-1H-in...)
Show SMILES CCCCCCCCCCOc1ccccc1CCC(=O)c1c(C(O)=O)n(C)c2ccccc12
Show InChI InChI=1S/C29H37NO4/c1-3-4-5-6-7-8-9-14-21-34-26-18-13-10-15-22(26)19-20-25(31)27-23-16-11-12-17-24(23)30(2)28(27)29(32)33/h10-13,15-18H,3-9,14,19-21H2,1-2H3,(H,32,33)
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n/an/a 3.40E+4n/an/an/an/an/an/a



Ludwig-Maximilians-University

Curated by ChEMBL


Assay Description
Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...

J Med Chem 40: 2694-705 (1997)


Article DOI: 10.1021/jm960863w
BindingDB Entry DOI: 10.7270/Q2NP23JK
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%