Found 4 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM85228
(N-(1-(2-((N-Methylsulfonyl)amino)ethyl)piperidin-4...)Show SMILES CC(C)n1nc(C(=O)NC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H29N5O3S/c1-14(2)24-17-7-5-4-6-16(17)18(22-24)19(25)21-15-8-11-23(12-9-15)13-10-20-28(3,26)27/h4-7,14-15,20H,8-13H2,1-3H3,(H,21,25) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by PDSP Ki Database
| |
J Med Chem 41: 1943-55 (1998)
Article DOI: 10.1021/jm970857f
BindingDB Entry DOI: 10.7270/Q26H4FZ3 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM85227
(N-(1-Benzylpiperidin-4-yl)-1-isopropylindazole-3-c...)Show SMILES CC(C)n1nc(C(=O)NC2CCN(Cc3ccccc3)CC2)c2ccccc12 Show InChI InChI=1S/C23H28N4O/c1-17(2)27-21-11-7-6-10-20(21)22(25-27)23(28)24-19-12-14-26(15-13-19)16-18-8-4-3-5-9-18/h3-11,17,19H,12-16H2,1-2H3,(H,24,28) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by PDSP Ki Database
| |
J Med Chem 41: 1943-55 (1998)
Article DOI: 10.1021/jm970857f
BindingDB Entry DOI: 10.7270/Q26H4FZ3 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM85225
(N-(2-(4-((Benzyloxycarbonyl)amino)-1-piperidinyl)-...)Show SMILES CC(C)n1nc(C(=O)NCCN2CCC(CC2)NC(=O)OCc2ccccc2)c2ccccc12 Show InChI InChI=1S/C26H33N5O3/c1-19(2)31-23-11-7-6-10-22(23)24(29-31)25(32)27-14-17-30-15-12-21(13-16-30)28-26(33)34-18-20-8-4-3-5-9-20/h3-11,19,21H,12-18H2,1-2H3,(H,27,32)(H,28,33) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by PDSP Ki Database
| |
J Med Chem 41: 1943-55 (1998)
Article DOI: 10.1021/jm970857f
BindingDB Entry DOI: 10.7270/Q26H4FZ3 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM85226
(N-(2-(4-(1-Adamantylcarboxamido)-1-piperidinyl)eth...)Show SMILES CC(C)n1nc(C(=O)NCCN2CCC(CC2)C23CC4CC(CC(C4)C2)C3)c2ccccc12 |TLB:24:19:26:25.23.22,24:23:18.19.20:26,THB:22:21:18:25.23.24,22:23:18:21.20.26| Show InChI InChI=1S/C28H40N4O/c1-19(2)32-25-6-4-3-5-24(25)26(30-32)27(33)29-9-12-31-10-7-23(8-11-31)28-16-20-13-21(17-28)15-22(14-20)18-28/h3-6,19-23H,7-18H2,1-2H3,(H,29,33) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by PDSP Ki Database
| |
J Med Chem 41: 1943-55 (1998)
Article DOI: 10.1021/jm970857f
BindingDB Entry DOI: 10.7270/Q26H4FZ3 |
More data for this
Ligand-Target Pair | |
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