Affinity Data by PubMed id=9804694

PubMed code 9804694

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
CAD protein (Homo sapiens (Human))	BDBM50020110 ((4S,6R)-6-Mercaptomethyl-2-oxo-hexahydro-pyrimidin...) Show SMILES OC(=O)[C@@H]1C[C@H](CS)NC(=O)N1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.				J Med Chem 41: 4550-5 (1998) Article DOI: 10.1021/jm970814z BindingDB Entry DOI: 10.7270/Q26D5S58
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
CAD protein (Homo sapiens (Human))	BDBM50291969 ((2R,4S)-4-Mercapto-4,6-dioxo-4lambda5-[1,4]azaph...) Show SMILES OC(=O)[C@H]1NC(=O)CP(O)(S)=C1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.				J Med Chem 41: 4550-5 (1998) Article DOI: 10.1021/jm970814z BindingDB Entry DOI: 10.7270/Q26D5S58
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
CAD protein (Homo sapiens (Human))	BDBM50291969 ((2R,4S)-4-Mercapto-4,6-dioxo-4lambda5-[1,4]azaph...) Show SMILES OC(=O)[C@H]1NC(=O)CP(O)(S)=C1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.				J Med Chem 41: 4550-5 (1998) Article DOI: 10.1021/jm970814z BindingDB Entry DOI: 10.7270/Q26D5S58
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
CAD protein (Homo sapiens (Human))	BDBM50067883 (4-Hydroxy-4,6-dioxo-4lambda5-[1,4]azaphosphinane...) Show SMILES OC(=O)C1NC(=O)CP(O)(O)=C1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.				J Med Chem 41: 4550-5 (1998) Article DOI: 10.1021/jm970814z BindingDB Entry DOI: 10.7270/Q26D5S58
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%