Affinity Data by PubMed id=9873388

PubMed code 9873388

Found 24 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50070574 (5-Bromo-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50070571 (5-Bromo-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50070566 (5-Bromo-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50070565 (5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50070569 (5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-y...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50070573 (5-Chloro-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]dia...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50070564 (5-Chloro-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-y...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50070570 (5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-y...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50070567 (5-Bromo-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]diaz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50070572 (6-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan...) Show SMILES CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(N)nc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50070568 (5-Bromo-6-dimethylamino-N-(1-ethyl-4-methyl-[1,4]d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070571 (5-Bromo-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070569 (5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-y...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070574 (5-Bromo-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070570 (5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-y...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070565 (5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070567 (5-Bromo-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]diaz...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070568 (5-Bromo-6-dimethylamino-N-(1-ethyl-4-methyl-[1,4]d...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070573 (5-Chloro-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]dia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070566 (5-Bromo-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-yl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070564 (5-Chloro-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-y...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50070572 (6-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan...) Show SMILES CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(N)nc1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	386	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM48320 (4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...) Show SMILES CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM48320 (4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...) Show SMILES CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 8: 1551-4 (1999) BindingDB Entry DOI: 10.7270/Q2CF9P7B
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%