Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243386 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-is...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243393 (5-chloro-N4-2-(isopropylsulfonyl)phenyl)-N2-(7-met...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243395 (5-chloro-N4-2-(isopropylsulfonyl)phenyl)-N2-(7-met...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243393 (5-chloro-N4-2-(isopropylsulfonyl)phenyl)-N2-(7-met...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50116683 (CHEMBL3608526 | US10053458, 49) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50116690 (CHEMBL3608528 | US10053458, 67) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50116696 (CHEMBL3608534 | US10053458, 52) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.550 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50116699 (CHEMBL3608642 | US10053458, 53) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.660 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116696 (CHEMBL3608534 | US10053458, 52) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50116685 (CHEMBL3608644 | US10053458, 54) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.780 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243402 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(6-me...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50116693 (CHEMBL3608531 | US10053458, 51) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50116692 (CHEMBL3608530 | US10053458, 59) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50116686 (CHEMBL3608313 | US10053458, 63) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243401 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-me...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243382 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-me...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243376 (1-6-(5-chloro-4-(2-(isopropylsulfonyl)phenylamino)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243431 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(6-me...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243370 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl-N2-(7-met...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50436850 (CERITINIB | CHEMBL2403108 | LDK378 | US10053458, C...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243425 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(6-me...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243373 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-me...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116699 (CHEMBL3608642 | US10053458, 53) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116680 (CHEMBL3608523 | US10053458, 56) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116685 (CHEMBL3608644 | US10053458, 54) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116693 (CHEMBL3608531 | US10053458, 51) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243388 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-is...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243432 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(6-me...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116683 (CHEMBL3608526 | US10053458, 49) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243386 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-is...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243401 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-me...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116687 (CHEMBL3608645 | US10053458, 55) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243390 (5-chloro-N2-(7-sec-butoxy-1,2,3,4-tetrahydroisoqui...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116691 (CHEMBL3608529 | US10053458, 50) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116679 (CHEMBL3608522 | US10053458, 47) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116665 (CHEMBL3608519 | US10053458, 48) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116681 (CHEMBL3608524 | US10053458, 65) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243381 (1-(6-(5-chloro-4-(2-(isopropylsulfonyl)phenylamino...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243382 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-me...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116688 (CHEMBL3608646 | US10053458, 64) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243395 (5-chloro-N4-2-(isopropylsulfonyl)phenyl)-N2-(7-met...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243431 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(6-me...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50116684 (CHEMBL3608643 | US10053458, 62) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50436850 (CERITINIB | CHEMBL2403108 | LDK378 | US10053458, C...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243370 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl-N2-(7-met...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243371 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-me...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243374 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-me...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243374 (5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-me...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM243379 (1-(6-(5-chloro-4-(2-(isopropylsulfonyl)phenylamino...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | Assay Description A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme... | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM243379 (1-(6-(5-chloro-4-(2-(isopropylsulfonyl)phenylamino...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent | US Patent US10053458 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZH9 | ||||||||||||
More data for this Ligand-Target Pair |
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