Affinity Data by USPatent=US10058549

USPatent US10058549

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM269506 ((4-(2-chlorophenethyl)piperazin-1- yl)(imidazo[1,2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	25
Arena Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding assays for human 5-HT2A serotonin receptor were conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific...				US Patent US10058549 (2018) BindingDB Entry DOI: 10.7270/Q2BK1FC8
Arena Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM269505 ((4-(2-fluoro-2-(4- fluorophenyl)ethyl)piperazin-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	25
Arena Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding assays for human 5-HT2A serotonin receptor were conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific...				US Patent US10058549 (2018) BindingDB Entry DOI: 10.7270/Q2BK1FC8
Arena Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM269504 ((4-(4-fluorophenethyl)piperazin-1- yl)(2-phenylimi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	7.4	25
Arena Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding assays for human 5-HT2A serotonin receptor were conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific...				US Patent US10058549 (2018) BindingDB Entry DOI: 10.7270/Q2BK1FC8
Arena Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair

* indicates data uncertainty>20%