BindingDB logo
myBDB logout

USPatent US10179769

Compile Data Set for Download or QSAR

Found 211 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314100
PNG
(3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(F)cc1
Show InChI InChI=1S/C13H11FN2O2/c14-10-3-1-9(2-4-10)7-16-12-8-15-6-5-11(12)13(17)18/h1-6,8,16H,7H2,(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314101
PNG
(3[(4-cyanobenzyl)amino]pyridine-4-carboxylic acid ...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(cc1)C#N
Show InChI InChI=1S/C14H11N3O2/c15-7-10-1-3-11(4-2-10)8-17-13-9-16-6-5-12(13)14(18)19/h1-6,9,17H,8H2,(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314105
PNG
(3-[(biphenyl-4-ylmethyl)amino]pyridine-4-carboxyli...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C19H16N2O2/c22-19(23)17-10-11-20-13-18(17)21-12-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-11,13,21H,12H2,(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314106
PNG
(3-[(4-chlorobenzyl)amino]pyridine-4-carboxylic aci...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(Cl)cc1
Show InChI InChI=1S/C13H11ClN2O2/c14-10-3-1-9(2-4-10)7-16-12-8-15-6-5-11(12)13(17)18/h1-6,8,16H,7H2,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314112
PNG
(3-[(2,4-dimethyoxybenzyl)amino]pyridine-4-carboxyl...)
Show SMILES COc1ccc(CNc2cnccc2C(O)=O)c(OC)c1
Show InChI InChI=1S/C15H16N2O4/c1-20-11-4-3-10(14(7-11)21-2)8-17-13-9-16-6-5-12(13)15(18)19/h3-7,9,17H,8H2,1-2H3,(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314117
PNG
(3-[(4-chloro-2-hydroxybenzyl)amino]pyridine-4-carb...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(Cl)cc1O
Show InChI InChI=1S/C13H11ClN2O3/c14-9-2-1-8(12(17)5-9)6-16-11-7-15-4-3-10(11)13(18)19/h1-5,7,16-17H,6H2,(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314117
PNG
(3-[(4-chloro-2-hydroxybenzyl)amino]pyridine-4-carb...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(Cl)cc1O
Show InChI InChI=1S/C13H11ClN2O3/c14-9-2-1-8(12(17)5-9)6-16-11-7-15-4-3-10(11)13(18)19/h1-5,7,16-17H,6H2,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314122
PNG
(3-[(4-chloro-2-cyclopropylbenzyl)amino]pyridine-4-...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(Cl)cc1C1CC1
Show InChI InChI=1S/C16H15ClN2O2/c17-12-4-3-11(14(7-12)10-1-2-10)8-19-15-9-18-6-5-13(15)16(20)21/h3-7,9-10,19H,1-2,8H2,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314130
PNG
(3-[(2-cyclopropyl-5-methylbenzyl)amino]pyridine-4-...)
Show SMILES Cc1ccc(C2CC2)c(CNc2cnccc2C(O)=O)c1
Show InChI InChI=1S/C17H18N2O2/c1-11-2-5-14(12-3-4-12)13(8-11)9-19-16-10-18-7-6-15(16)17(20)21/h2,5-8,10,12,19H,3-4,9H2,1H3,(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM50158791
PNG
(CHEMBL3786596 | US10179769, Example 42 | US1080795...)
Show SMILES OC(=O)c1ccncc1NCC12CC3CC(CC(C3)C1)C2 |TLB:18:13:20:16.17.19,18:17:20:14.13.12,THB:16:15:12:18.17.19,16:17:14.15.20:12|
Show InChI InChI=1S/C17H22N2O2/c20-16(21)14-1-2-18-9-15(14)19-10-17-6-11-3-12(7-17)5-13(4-11)8-17/h1-2,9,11-13,19H,3-8,10H2,(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314143
PNG
(3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]a...)
Show SMILES OC(=O)c1ccncc1NC[C@H]1CCCc2ccccc12 |r|
Show InChI InChI=1S/C17H18N2O2/c20-17(21)15-8-9-18-11-16(15)19-10-13-6-3-5-12-4-1-2-7-14(12)13/h1-2,4,7-9,11,13,19H,3,5-6,10H2,(H,20,21)/t13-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314154
PNG
(3-{[(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)m...)
Show SMILES COc1ccc2C(CNc3cnccc3C(O)=O)CCCc2c1
Show InChI InChI=1S/C18H20N2O3/c1-23-14-5-6-15-12(9-14)3-2-4-13(15)10-20-17-11-19-8-7-16(17)18(21)22/h5-9,11,13,20H,2-4,10H2,1H3,(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314097
PNG
(3-(benzylamino)pyridazine-4-carboxylic acid | US10...)
Show SMILES OC(=O)c1ccnnc1NCc1ccccc1
Show InChI InChI=1S/C12H11N3O2/c16-12(17)10-6-7-14-15-11(10)13-8-9-4-2-1-3-5-9/h1-7H,8H2,(H,13,15)(H,16,17)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314099
PNG
(3-[(3-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Show SMILES OC(=O)c1ccncc1NCc1cccc(F)c1
Show InChI InChI=1S/C13H11FN2O2/c14-10-3-1-2-9(6-10)7-16-12-8-15-5-4-11(12)13(17)18/h1-6,8,16H,7H2,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314102
PNG
(3-{[4-hydroxymethyl)benzyl]amino}pyridine-4-carbox...)
Show SMILES OCc1ccc(CNc2cnccc2C(O)=O)cc1
Show InChI InChI=1S/C14H14N2O3/c17-9-11-3-1-10(2-4-11)7-16-13-8-15-6-5-12(13)14(18)19/h1-6,8,16-17H,7,9H2,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314103
PNG
(3-[(4-methoxybenzyl)amino]pyridine-4-carboxylic ac...)
Show SMILES COc1ccc(CNc2cnccc2C(O)=O)cc1
Show InChI InChI=1S/C14H14N2O3/c1-19-11-4-2-10(3-5-11)8-16-13-9-15-7-6-12(13)14(17)18/h2-7,9,16H,8H2,1H3,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314110
PNG
(3-[(3,4-dichlorobenzyl)amino]pyridine-4-carboxylic...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H10Cl2N2O2/c14-10-2-1-8(5-11(10)15)6-17-12-7-16-4-3-9(12)13(18)19/h1-5,7,17H,6H2,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314111
PNG
(3-[(4-chloro-2-methylbenzyl)amino]pyridine-4-carbo...)
Show SMILES Cc1cc(Cl)ccc1CNc1cnccc1C(O)=O
Show InChI InChI=1S/C14H13ClN2O2/c1-9-6-11(15)3-2-10(9)7-17-13-8-16-5-4-12(13)14(18)19/h2-6,8,17H,7H2,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314113
PNG
(3-[(2-hydroxybenzyl)amino]pyridine-4-carboxylic ac...)
Show SMILES OC(=O)c1ccncc1NCc1ccccc1O
Show InChI InChI=1S/C13H12N2O3/c16-12-4-2-1-3-9(12)7-15-11-8-14-6-5-10(11)13(17)18/h1-6,8,15-16H,7H2,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314114
PNG
(3-[(2,4-dichlorobenzyl)amino]pyridine-4-carboxylic...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C13H10Cl2N2O2/c14-9-2-1-8(11(15)5-9)6-17-12-7-16-4-3-10(12)13(18)19/h1-5,7,17H,6H2,(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314115
PNG
(3-[(2-cyclopropylbenzyl)amino]pyridine-4-carboxyli...)
Show SMILES OC(=O)c1ccncc1NCc1ccccc1C1CC1
Show InChI InChI=1S/C16H16N2O2/c19-16(20)14-7-8-17-10-15(14)18-9-12-3-1-2-4-13(12)11-5-6-11/h1-4,7-8,10-11,18H,5-6,9H2,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314120
PNG
(3-[(4-methylbenzyl)amino]pyridine-4-carboxylic aci...)
Show SMILES Cc1ccc(CNc2cnccc2C(O)=O)cc1
Show InChI InChI=1S/C14H14N2O2/c1-10-2-4-11(5-3-10)8-16-13-9-15-7-6-12(13)14(17)18/h2-7,9,16H,8H2,1H3,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314123
PNG
(3-{[2-cyclopropyl-4-(trifluoromethyl)benzyl]amino}...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(cc1C1CC1)C(F)(F)F
Show InChI InChI=1S/C17H15F3N2O2/c18-17(19,20)12-4-3-11(14(7-12)10-1-2-10)8-22-15-9-21-6-5-13(15)16(23)24/h3-7,9-10,22H,1-2,8H2,(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314123
PNG
(3-{[2-cyclopropyl-4-(trifluoromethyl)benzyl]amino}...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(cc1C1CC1)C(F)(F)F
Show InChI InChI=1S/C17H15F3N2O2/c18-17(19,20)12-4-3-11(14(7-12)10-1-2-10)8-22-15-9-21-6-5-13(15)16(23)24/h3-7,9-10,22H,1-2,8H2,(H,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314124
PNG
(3-[(naphthalene-1-ylmethyl)amino]pyridine-4-carbox...)
Show SMILES OC(=O)c1ccncc1NCc1cccc2ccccc12
Show InChI InChI=1S/C17H14N2O2/c20-17(21)15-8-9-18-11-16(15)19-10-13-6-3-5-12-4-1-2-7-14(12)13/h1-9,11,19H,10H2,(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314127
PNG
(3-{[(4-cyclopropylpyridin-3-yl)-methyl]amino}pyrid...)
Show SMILES OC(=O)c1ccncc1NCc1cnccc1C1CC1
Show InChI InChI=1S/C15H15N3O2/c19-15(20)13-4-6-17-9-14(13)18-8-11-7-16-5-3-12(11)10-1-2-10/h3-7,9-10,18H,1-2,8H2,(H,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314128
PNG
(3-{[3-(trifluoromethyl)benzyl]amino}pyridine-4-car...)
Show SMILES OC(=O)c1ccncc1NCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C14H11F3N2O2/c15-14(16,17)10-3-1-2-9(6-10)7-19-12-8-18-5-4-11(12)13(20)21/h1-6,8,19H,7H2,(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314129
PNG
(3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...)
Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1
Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314134
PNG
(3-[(1-benzofuran-3-ylmethyl)amino]pyridine-4-carbo...)
Show SMILES OC(=O)c1ccncc1NCc1coc2ccccc12
Show InChI InChI=1S/C15H12N2O3/c18-15(19)12-5-6-16-8-13(12)17-7-10-9-20-14-4-2-1-3-11(10)14/h1-6,8-9,17H,7H2,(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314152
PNG
(3-[(3,4-dihydro-2H-chromen-4-ylmethyl)amino]pyridi...)
Show SMILES OC(=O)c1ccncc1NCC1CCOc2ccccc12
Show InChI InChI=1S/C16H16N2O3/c19-16(20)13-5-7-17-10-14(13)18-9-11-6-8-21-15-4-2-1-3-12(11)15/h1-5,7,10-11,18H,6,8-9H2,(H,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314100
PNG
(3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(F)cc1
Show InChI InChI=1S/C13H11FN2O2/c14-10-3-1-9(2-4-10)7-16-12-8-15-6-5-11(12)13(17)18/h1-6,8,16H,7H2,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314101
PNG
(3[(4-cyanobenzyl)amino]pyridine-4-carboxylic acid ...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(cc1)C#N
Show InChI InChI=1S/C14H11N3O2/c15-7-10-1-3-11(4-2-10)8-17-13-9-16-6-5-12(13)14(18)19/h1-6,9,17H,8H2,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314109
PNG
(3-({2-[(dimethylamino)methyl]benzyl}amino)pyridine...)
Show SMILES CN(C)Cc1ccccc1CNc1cnccc1C(O)=O
Show InChI InChI=1S/C16H19N3O2/c1-19(2)11-13-6-4-3-5-12(13)9-18-15-10-17-8-7-14(15)16(20)21/h3-8,10,18H,9,11H2,1-2H3,(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314111
PNG
(3-[(4-chloro-2-methylbenzyl)amino]pyridine-4-carbo...)
Show SMILES Cc1cc(Cl)ccc1CNc1cnccc1C(O)=O
Show InChI InChI=1S/C14H13ClN2O2/c1-9-6-11(15)3-2-10(9)7-17-13-8-16-5-4-12(13)14(18)19/h2-6,8,17H,7H2,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314113
PNG
(3-[(2-hydroxybenzyl)amino]pyridine-4-carboxylic ac...)
Show SMILES OC(=O)c1ccncc1NCc1ccccc1O
Show InChI InChI=1S/C13H12N2O3/c16-12-4-2-1-3-9(12)7-15-11-8-14-6-5-10(11)13(17)18/h1-6,8,15-16H,7H2,(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314114
PNG
(3-[(2,4-dichlorobenzyl)amino]pyridine-4-carboxylic...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C13H10Cl2N2O2/c14-9-2-1-8(11(15)5-9)6-17-12-7-16-4-3-10(12)13(18)19/h1-5,7,17H,6H2,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314133
PNG
(3-{[3-(cyclopropylmethoxy)benzyl]amino}pyridine-4-...)
Show SMILES OC(=O)c1ccncc1NCc1cccc(OCC2CC2)c1
Show InChI InChI=1S/C17H18N2O3/c20-17(21)15-6-7-18-10-16(15)19-9-13-2-1-3-14(8-13)22-11-12-4-5-12/h1-3,6-8,10,12,19H,4-5,9,11H2,(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314139
PNG
(3-[(2,3-dihydro-1-benzofuran-2-ylmethyl)amino]pyri...)
Show SMILES OC(=O)c1ccncc1NCC1Cc2ccccc2O1
Show InChI InChI=1S/C15H14N2O3/c18-15(19)12-5-6-16-9-13(12)17-8-11-7-10-3-1-2-4-14(10)20-11/h1-6,9,11,17H,7-8H2,(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314142
PNG
(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)
Show SMILES OC(=O)c1ccncc1NCC1CCCc2ccccc12
Show InChI InChI=1S/C17H18N2O2/c20-17(21)15-8-9-18-11-16(15)19-10-13-6-3-5-12-4-1-2-7-14(12)13/h1-2,4,7-9,11,13,19H,3,5-6,10H2,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314148
PNG
(3-{[(7-cyclopropyl-1,2,3,4-tetrahydronaphthalen-1-...)
Show SMILES OC(=O)c1ccncc1NCC1CCCc2ccc(cc12)C1CC1
Show InChI InChI=1S/C20H22N2O2/c23-20(24)17-8-9-21-12-19(17)22-11-16-3-1-2-14-6-7-15(10-18(14)16)13-4-5-13/h6-10,12-13,16,22H,1-5,11H2,(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314156
PNG
(3-{[(6-methyl-3,4-dihydro-2H-chromen-4-yl)methyl]a...)
Show SMILES Cc1ccc2OCCC(CNc3cnccc3C(O)=O)c2c1
Show InChI InChI=1S/C17H18N2O3/c1-11-2-3-16-14(8-11)12(5-7-22-16)9-19-15-10-18-6-4-13(15)17(20)21/h2-4,6,8,10,12,19H,5,7,9H2,1H3,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314164
PNG
(3-{[(8-fluoro-3,4-dihydro-2H-chromen-4-yl)methyl]a...)
Show SMILES OC(=O)c1ccncc1NCC1CCOc2c(F)cccc12
Show InChI InChI=1S/C16H15FN2O3/c17-13-3-1-2-11-10(5-7-22-15(11)13)8-19-14-9-18-6-4-12(14)16(20)21/h1-4,6,9-10,19H,5,7-8H2,(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314178
PNG
(3-({[(4S)-7-cyclopropyl-3,4-dihydro-2H-chromen-4-y...)
Show SMILES OC(=O)c1ccncc1NC[C@H]1CCOc2cc(ccc12)C1CC1 |r|
Show InChI InChI=1S/C19H20N2O3/c22-19(23)16-5-7-20-11-17(16)21-10-14-6-8-24-18-9-13(12-1-2-12)3-4-15(14)18/h3-5,7,9,11-12,14,21H,1-2,6,8,10H2,(H,22,23)/t14-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314098
PNG
(3-[(2-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Show SMILES OC(=O)c1ccncc1NCc1ccccc1F
Show InChI InChI=1S/C13H11FN2O2/c14-11-4-2-1-3-9(11)7-16-12-8-15-6-5-10(12)13(17)18/h1-6,8,16H,7H2,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314099
PNG
(3-[(3-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Show SMILES OC(=O)c1ccncc1NCc1cccc(F)c1
Show InChI InChI=1S/C13H11FN2O2/c14-10-3-1-2-9(6-10)7-16-12-8-15-5-4-11(12)13(17)18/h1-6,8,16H,7H2,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314103
PNG
(3-[(4-methoxybenzyl)amino]pyridine-4-carboxylic ac...)
Show SMILES COc1ccc(CNc2cnccc2C(O)=O)cc1
Show InChI InChI=1S/C14H14N2O3/c1-19-11-4-2-10(3-5-11)8-16-13-9-15-7-6-12(13)14(17)18/h2-7,9,16H,8H2,1H3,(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314104
PNG
(3-{[4-(trifluoromethyl)benzyl]amino}pyridine-4-car...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C14H11F3N2O2/c15-14(16,17)10-3-1-9(2-4-10)7-19-12-8-18-6-5-11(12)13(20)21/h1-6,8,19H,7H2,(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314106
PNG
(3-[(4-chlorobenzyl)amino]pyridine-4-carboxylic aci...)
Show SMILES OC(=O)c1ccncc1NCc1ccc(Cl)cc1
Show InChI InChI=1S/C13H11ClN2O2/c14-10-3-1-9(2-4-10)7-16-12-8-15-6-5-11(12)13(17)18/h1-6,8,16H,7H2,(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))		BDBM314109
PNG
(3-({2-[(dimethylamino)methyl]benzyl}amino)pyridine...)
Show SMILES CN(C)Cc1ccccc1CNc1cnccc1C(O)=O
Show InChI InChI=1S/C16H19N3O2/c1-19(2)11-13-6-4-3-5-12(13)9-18-15-10-17-8-7-14(15)16(20)21/h3-8,10,18H,9,11H2,1-2H3,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM314113
PNG
(3-[(2-hydroxybenzyl)amino]pyridine-4-carboxylic ac...)
Show SMILES OC(=O)c1ccncc1NCc1ccccc1O
Show InChI InChI=1S/C13H12N2O3/c16-12-4-2-1-3-9(12)7-15-11-8-14-6-5-10(11)13(17)18/h1-6,8,15-16H,7H2,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...

US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 211 total )  |  Next  |  Last  >>
* indicates data uncertainty>20%