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USPatent US10221129

Compile Data Set for Download or QSAR

Found 293 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359198
PNG
(US10221129, Example JB-1)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)N1CCc2ccccc12 |r|
Show InChI InChI=1S/C26H28N4O5S/c1-29(21-12-14-22(35-2)15-13-21)25(31)23(18-19-8-4-3-5-9-19)27-26(32)28-36(33,34)30-17-16-20-10-6-7-11-24(20)30/h3-15,23H,16-18H2,1-2H3,(H2,27,28,32)/t23-/m0/s1
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n/an/an/an/a 110n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359201
PNG
(US10221129, Example JB-12)
Show SMILES COc1ccccc1NS(=O)(=O)NC(=O)N[C@@H](Cc1ccccc1)C(=O)N(C)c1ccc2ncccc2c1 |r|
Show InChI InChI=1S/C27H27N5O5S/c1-32(21-14-15-22-20(18-21)11-8-16-28-22)26(33)24(17-19-9-4-3-5-10-19)29-27(34)31-38(35,36)30-23-12-6-7-13-25(23)37-2/h3-16,18,24,30H,17H2,1-2H3,(H2,29,31,34)/t24-/m0/s1
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n/an/an/an/a 170n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359207
PNG
(US10221129, Example JB-18)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)N(C)c1ccccc1C |r|
Show InChI InChI=1S/C26H30N4O5S/c1-19-10-8-9-13-24(19)30(3)36(33,34)28-26(32)27-23(18-20-11-6-5-7-12-20)25(31)29(2)21-14-16-22(35-4)17-15-21/h5-17,23H,18H2,1-4H3,(H2,27,28,32)/t23-/m0/s1
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n/an/an/an/a 560n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359227
PNG
(US10221129, Example JB-37)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)N(C)c1cccc(Cl)c1 |r|
Show InChI InChI=1S/C25H27ClN4O5S/c1-29(20-12-14-22(35-3)15-13-20)24(31)23(16-18-8-5-4-6-9-18)27-25(32)28-36(33,34)30(2)21-11-7-10-19(26)17-21/h4-15,17,23H,16H2,1-3H3,(H2,27,28,32)/t23-/m0/s1
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n/an/an/an/a 60n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359256
PNG
(US10221129, Example JB-66 | US10221129, Example JB...)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)NCc1n[nH]c2ccccc12 |r|
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n/an/an/an/a 1.18E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359285
PNG
(US10221129, Example CA-19)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1ccc(cc1)C(C)=O |r|
Show InChI InChI=1S/C26H28N4O6S/c1-18(31)20-9-11-21(12-10-20)28-37(34,35)29-26(33)27-24(17-19-7-5-4-6-8-19)25(32)30(2)22-13-15-23(36-3)16-14-22/h4-16,24,28H,17H2,1-3H3,(H2,27,29,33)/t24-/m0/s1
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n/an/an/an/a 120n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359301
PNG
(US10221129, Example CA-35)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1cccc(OC(F)(F)F)c1 |r|
Show InChI InChI=1S/C25H25F3N4O6S/c1-32(19-11-13-20(37-2)14-12-19)23(33)22(15-17-7-4-3-5-8-17)29-24(34)31-39(35,36)30-18-9-6-10-21(16-18)38-25(26,27)28/h3-14,16,22,30H,15H2,1-2H3,(H2,29,31,34)/t22-/m0/s1
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n/an/an/an/a 380n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359303
PNG
(US10221129, Example CA-37)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1cccc(c1)-c1ccccc1 |r|
Show InChI InChI=1S/C30H30N4O5S/c1-34(26-16-18-27(39-2)19-17-26)29(35)28(20-22-10-5-3-6-11-22)31-30(36)33-40(37,38)32-25-15-9-14-24(21-25)23-12-7-4-8-13-23/h3-19,21,28,32H,20H2,1-2H3,(H2,31,33,36)/t28-/m0/s1
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n/an/an/an/a 1.20E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359308
PNG
(US10221129, Example CA-42)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1ccccc1NC(C)=O |r|
Show InChI InChI=1S/C26H29N5O6S/c1-18(32)27-22-11-7-8-12-23(22)29-38(35,36)30-26(34)28-24(17-19-9-5-4-6-10-19)25(33)31(2)20-13-15-21(37-3)16-14-20/h4-16,24,29H,17H2,1-3H3,(H,27,32)(H2,28,30,34)/t24-/m0/s1
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n/an/an/an/a 4.12E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359314
PNG
(US10221129, Example CA-48)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1ccc2CS(=O)(=O)Cc2c1 |r|
Show InChI InChI=1S/C26H28N4O7S2/c1-30(22-10-12-23(37-2)13-11-22)25(31)24(14-18-6-4-3-5-7-18)27-26(32)29-39(35,36)28-21-9-8-19-16-38(33,34)17-20(19)15-21/h3-13,15,24,28H,14,16-17H2,1-2H3,(H2,27,29,32)/t24-/m0/s1
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n/an/an/an/a 260n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359317
PNG
(US10221129, Example CA-51)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)NCC(=O)N1CCCC1 |r|
Show InChI InChI=1S/C24H31N5O6S/c1-28(19-10-12-20(35-2)13-11-19)23(31)21(16-18-8-4-3-5-9-18)26-24(32)27-36(33,34)25-17-22(30)29-14-6-7-15-29/h3-5,8-13,21,25H,6-7,14-17H2,1-2H3,(H2,26,27,32)/t21-/m0/s1
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n/an/an/an/a 4.59E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359320
PNG
(US10221129, Example CA-58)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)NCC(=O)N1CCN(CC1)c1ccccc1 |r|
Show InChI InChI=1S/C30H36N6O6S/c1-34(24-13-15-26(42-2)16-14-24)29(38)27(21-23-9-5-3-6-10-23)32-30(39)33-43(40,41)31-22-28(37)36-19-17-35(18-20-36)25-11-7-4-8-12-25/h3-16,27,31H,17-22H2,1-2H3,(H2,32,33,39)/t27-/m0/s1
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n/an/an/an/a 7.45E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359324
PNG
(US10221129, Example JB-78)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)n1ccc2c(F)c(F)c(F)c(F)c12 |r|
Show InChI InChI=1S/C26H22F4N4O5S/c1-33(16-8-10-17(39-2)11-9-16)25(35)19(14-15-6-4-3-5-7-15)31-26(36)32-40(37,38)34-13-12-18-20(27)21(28)22(29)23(30)24(18)34/h3-13,19H,14H2,1-2H3,(H2,31,32,36)/t19-/m0/s1
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n/an/an/an/a 370n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359326
PNG
(US10221129, Example JB-80)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)n1ccc2cnccc12 |r|
Show InChI InChI=1S/C25H25N5O5S/c1-29(20-8-10-21(35-2)11-9-20)24(31)22(16-18-6-4-3-5-7-18)27-25(32)28-36(33,34)30-15-13-19-17-26-14-12-23(19)30/h3-15,17,22H,16H2,1-2H3,(H2,27,28,32)/t22-/m0/s1
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n/an/an/an/a 360n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359329
PNG
(US10221129, Example CA-62)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)n1c(C)cc2ccncc12 |r|
Show InChI InChI=1S/C26H27N5O5S/c1-18-15-20-13-14-27-17-24(20)31(18)37(34,35)29-26(33)28-23(16-19-7-5-4-6-8-19)25(32)30(2)21-9-11-22(36-3)12-10-21/h4-15,17,23H,16H2,1-3H3,(H2,28,29,33)/t23-/m0/s1
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n/an/an/an/a 3.69E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359330
PNG
(US10221129, Example CA-63)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)n1nc(-c2ccccc2)c2ccccc12 |r|
Show InChI InChI=1S/C31H29N5O5S/c1-35(24-17-19-25(41-2)20-18-24)30(37)27(21-22-11-5-3-6-12-22)32-31(38)34-42(39,40)36-28-16-10-9-15-26(28)29(33-36)23-13-7-4-8-14-23/h3-20,27H,21H2,1-2H3,(H2,32,34,38)/t27-/m0/s1
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n/an/an/an/a 3.02E+4n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359333
PNG
(US10221129, Example CA-66)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)n1ncc2c(Cl)nc(Cl)cc12 |r|
Show InChI InChI=1S/C24H22Cl2N6O5S/c1-31(16-8-10-17(37-2)11-9-16)23(33)19(12-15-6-4-3-5-7-15)28-24(34)30-38(35,36)32-20-13-21(25)29-22(26)18(20)14-27-32/h3-11,13-14,19H,12H2,1-2H3,(H2,28,30,34)/t19-/m0/s1
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n/an/an/an/a 1.46E+4n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359342
PNG
(US10221129, Example ZY-18)
Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)n1ccc2nccnc12)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C24H19F2N7O4S2/c1-32(17-2-3-21-19(12-17)29-13-38-21)23(34)20(10-14-8-15(25)11-16(26)9-14)30-24(35)31-39(36,37)33-7-4-18-22(33)28-6-5-27-18/h2-9,11-13,20H,10H2,1H3,(H2,30,31,35)/t20-/m0/s1
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n/an/an/an/a 150n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359343
PNG
(US10221129, Example CA-113)
Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)N(C)c1ccccn1)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C24H22F2N6O4S2/c1-31(18-6-7-21-19(13-18)28-14-37-21)23(33)20(11-15-9-16(25)12-17(26)10-15)29-24(34)30-38(35,36)32(2)22-5-3-4-8-27-22/h3-10,12-14,20H,11H2,1-2H3,(H2,29,30,34)/t20-/m0/s1
PDB

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n/an/an/an/a 140n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359348
PNG
(US10221129, Example CA-118)
Show SMILES COc1ccc(cn1)N(C)S(=O)(=O)NC(=O)N[C@@H](Cc1cc(F)cc(F)c1)C(=O)N(C)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C25H24F2N6O5S2/c1-32(18-4-6-22-20(12-18)29-14-39-22)24(34)21(10-15-8-16(26)11-17(27)9-15)30-25(35)31-40(36,37)33(2)19-5-7-23(38-3)28-13-19/h4-9,11-14,21H,10H2,1-3H3,(H2,30,31,35)/t21-/m0/s1
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n/an/an/an/a 160n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359370
PNG
(US10221129, Example VN-14 | US10221129, Example VN...)
Show SMILES CC1CN(c2ncccc12)S(=O)(=O)NC(=O)N[C@@H](Cc1cc(F)cc(F)c1)C(=O)N(C)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C26H24F2N6O4S2/c1-15-13-34(24-20(15)4-3-7-29-24)40(37,38)32-26(36)31-22(10-16-8-17(27)11-18(28)9-16)25(35)33(2)19-5-6-23-21(12-19)30-14-39-23/h3-9,11-12,14-15,22H,10,13H2,1-2H3,(H2,31,32,36)/t15?,22-/m0/s1
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n/an/an/an/a<10n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359370
PNG
(US10221129, Example VN-14 | US10221129, Example VN...)
Show SMILES CC1CN(c2ncccc12)S(=O)(=O)NC(=O)N[C@@H](Cc1cc(F)cc(F)c1)C(=O)N(C)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C26H24F2N6O4S2/c1-15-13-34(24-20(15)4-3-7-29-24)40(37,38)32-26(36)31-22(10-16-8-17(27)11-18(28)9-16)25(35)33(2)19-5-6-23-21(12-19)30-14-39-23/h3-9,11-12,14-15,22H,10,13H2,1-2H3,(H2,31,32,36)/t15?,22-/m0/s1
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VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359378
PNG
(US10221129, Example GW-4)
Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)N1CCc2cccnc12)c1ccc(C)cn1 |r|
Show InChI InChI=1S/C24H24F2N6O4S/c1-15-5-6-21(28-14-15)31(2)23(33)20(12-16-10-18(25)13-19(26)11-16)29-24(34)30-37(35,36)32-9-7-17-4-3-8-27-22(17)32/h3-6,8,10-11,13-14,20H,7,9,12H2,1-2H3,(H2,29,30,34)/t20-/m0/s1
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n/an/an/an/a 220n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359383
PNG
(US10221129, Example BB-3)
Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)N1CCc2cccnc12)c1ccc(cc1)N1CCOCC1 |r|
Show InChI InChI=1S/C28H30F2N6O5S/c1-34(23-4-6-24(7-5-23)35-11-13-41-14-12-35)27(37)25(17-19-15-21(29)18-22(30)16-19)32-28(38)33-42(39,40)36-10-8-20-3-2-9-31-26(20)36/h2-7,9,15-16,18,25H,8,10-14,17H2,1H3,(H2,32,33,38)/t25-/m0/s1
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VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359384
PNG
(US10221129, Example BB-4)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)N1CCc2c1nccc2Cl |r|
Show InChI InChI=1S/C25H24ClF2N5O5S/c1-32(18-3-5-19(38-2)6-4-18)24(34)22(13-15-11-16(27)14-17(28)12-15)30-25(35)31-39(36,37)33-10-8-20-21(26)7-9-29-23(20)33/h3-7,9,11-12,14,22H,8,10,13H2,1-2H3,(H2,30,31,35)/t22-/m0/s1
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VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359395
PNG
(US10221129, Example BB-10)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)N1CCc2ccncc12 |r|
Show InChI InChI=1S/C25H25F2N5O5S/c1-31(20-3-5-21(37-2)6-4-20)24(33)22(13-16-11-18(26)14-19(27)12-16)29-25(34)30-38(35,36)32-10-8-17-7-9-28-15-23(17)32/h3-7,9,11-12,14-15,22H,8,10,13H2,1-2H3,(H2,29,30,34)/t22-/m0/s1
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n/an/an/an/a 1.08E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359410
PNG
(US10221129, Example VN-22)
Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)N1CCCC1)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C22H23F2N5O4S2/c1-28(17-4-5-20-18(12-17)25-13-34-20)21(30)19(10-14-8-15(23)11-16(24)9-14)26-22(31)27-35(32,33)29-6-2-3-7-29/h4-5,8-9,11-13,19H,2-3,6-7,10H2,1H3,(H2,26,27,31)/t19-/m0/s1
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VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359412
PNG
(US10221129, Example VN-24)
Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)N1CCCCC1)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C23H25F2N5O4S2/c1-29(18-5-6-21-19(13-18)26-14-35-21)22(31)20(11-15-9-16(24)12-17(25)10-15)27-23(32)28-36(33,34)30-7-3-2-4-8-30/h5-6,9-10,12-14,20H,2-4,7-8,11H2,1H3,(H2,27,28,32)/t20-/m0/s1
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VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359418
PNG
(US10221129, Example BB-20)
Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)N1CCc2cccnc12)c1ccc(C)c(Cl)c1 |r|
Show InChI InChI=1S/C25H24ClF2N5O4S/c1-15-5-6-20(14-21(15)26)32(2)24(34)22(12-16-10-18(27)13-19(28)11-16)30-25(35)31-38(36,37)33-9-7-17-4-3-8-29-23(17)33/h3-6,8,10-11,13-14,22H,7,9,12H2,1-2H3,(H2,30,31,35)/t22-/m0/s1
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VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359422
PNG
(US10221129, Example AW-3)
Show SMILES COc1ccc(cc1F)N(C)C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)N1CCC(F)(F)CC1 |r|
Show InChI InChI=1S/C23H25F5N4O5S/c1-31(17-3-4-20(37-2)18(26)13-17)21(33)19(11-14-9-15(24)12-16(25)10-14)29-22(34)30-38(35,36)32-7-5-23(27,28)6-8-32/h3-4,9-10,12-13,19H,5-8,11H2,1-2H3,(H2,29,30,34)/t19-/m0/s1
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VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359424
PNG
(US10221129, Example BB-21)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)N1CCC[C@H]1C(=O)N(C)C |r|
Show InChI InChI=1S/C25H31F2N5O6S/c1-30(2)24(34)22-6-5-11-32(22)39(36,37)29-25(35)28-21(14-16-12-17(26)15-18(27)13-16)23(33)31(3)19-7-9-20(38-4)10-8-19/h7-10,12-13,15,21-22H,5-6,11,14H2,1-4H3,(H2,28,29,35)/t21-,22-/m0/s1
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VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359432
PNG
(US10221129, Example BB-26)
Show SMILES CN(C)C(=O)[C@H]1CCCN1S(=O)(=O)NC(=O)N[C@@H](Cc1cc(F)cc(F)c1)C(=O)N(C)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C25H28F2N6O5S2/c1-31(2)24(35)21-5-4-8-33(21)40(37,38)30-25(36)29-20(11-15-9-16(26)12-17(27)10-15)23(34)32(3)18-6-7-22-19(13-18)28-14-39-22/h6-7,9-10,12-14,20-21H,4-5,8,11H2,1-3H3,(H2,29,30,36)/t20-,21+/m0/s1
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VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359440
PNG
(US10221129, Example CA-128)
Show SMILES COC1CN(C1)S(=O)(=O)NC(=O)N[C@@H](Cc1cc(F)cc(F)c1)C(=O)N(C)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C22H23F2N5O5S2/c1-28(16-3-4-20-18(9-16)25-12-35-20)21(30)19(7-13-5-14(23)8-15(24)6-13)26-22(31)27-36(32,33)29-10-17(11-29)34-2/h3-6,8-9,12,17,19H,7,10-11H2,1-2H3,(H2,26,27,31)/t19-/m0/s1
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VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359448
PNG
(US10221129, Example CA-135)
Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)NCc1cccnc1)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C24H22F2N6O4S2/c1-32(19-4-5-22-20(11-19)28-14-37-22)23(33)21(9-16-7-17(25)10-18(26)8-16)30-24(34)31-38(35,36)29-13-15-3-2-6-27-12-15/h2-8,10-12,14,21,29H,9,13H2,1H3,(H2,30,31,34)/t21-/m0/s1
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n/an/an/an/a 1.53E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359451
PNG
(US10221129, Example CA-138)
Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)NCCO)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C20H21F2N5O5S2/c1-27(15-2-3-18-16(10-15)23-11-33-18)19(29)17(8-12-6-13(21)9-14(22)7-12)25-20(30)26-34(31,32)24-4-5-28/h2-3,6-7,9-11,17,24,28H,4-5,8H2,1H3,(H2,25,26,30)/t17-/m0/s1
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n/an/an/an/a 270n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359471
PNG
(US10221129, Example CA-158)
Show SMILES CN(C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)NS(=O)(=O)NCCc1ccccc1)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C26H25F2N5O4S2/c1-33(21-7-8-24-22(15-21)29-16-38-24)25(34)23(13-18-11-19(27)14-20(28)12-18)31-26(35)32-39(36,37)30-10-9-17-5-3-2-4-6-17/h2-8,11-12,14-16,23,30H,9-10,13H2,1H3,(H2,31,32,35)/t23-/m0/s1
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n/an/an/an/a 340n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359473
PNG
(US10221129, Example BB-29)
Show SMILES CN(C)C(=O)C1Cc2cccnc2N1S(=O)(=O)NC(=O)N[C@H](Cc1cc(F)cc(F)c1)C(=O)N(C)c1ccc2scnc2c1 |r|
Show InChI InChI=1S/C28H27F2N7O5S2/c1-35(2)27(39)23-12-17-5-4-8-31-25(17)37(23)44(41,42)34-28(40)33-22(11-16-9-18(29)13-19(30)10-16)26(38)36(3)20-6-7-24-21(14-20)32-15-43-24/h4-10,13-15,22-23H,11-12H2,1-3H3,(H2,33,34,40)/t22-,23?/m1/s1
PDB

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n/an/an/an/a 2.43E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359482
PNG
(US10221129, Example BB-36)
Show SMILES CCN(CC)S(=O)(=O)NC(=O)N[C@@H](Cc1cc(F)cc(F)c1)C(=O)N(C)c1ccc(OC(F)F)cc1 |r|
Show InChI InChI=1S/C22H26F4N4O5S/c1-4-30(5-2)36(33,34)28-22(32)27-19(12-14-10-15(23)13-16(24)11-14)20(31)29(3)17-6-8-18(9-7-17)35-21(25)26/h6-11,13,19,21H,4-5,12H2,1-3H3,(H2,27,28,32)/t19-/m0/s1
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n/an/an/an/a 160n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359192
PNG
(US10221129, Example JB-3)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)N(C)c1ccccc1 |r|
Show InChI InChI=1S/C25H28N4O5S/c1-28(20-14-16-22(34-3)17-15-20)24(30)23(18-19-10-6-4-7-11-19)26-25(31)27-35(32,33)29(2)21-12-8-5-9-13-21/h4-17,23H,18H2,1-3H3,(H2,26,27,31)/t23-/m0/s1
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n/an/an/an/a 130n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359194
PNG
(US10221129, Example JB-5)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1ccccc1Cl |r|
Show InChI InChI=1S/C24H25ClN4O5S/c1-29(18-12-14-19(34-2)15-13-18)23(30)22(16-17-8-4-3-5-9-17)26-24(31)28-35(32,33)27-21-11-7-6-10-20(21)25/h3-15,22,27H,16H2,1-2H3,(H2,26,28,31)/t22-/m0/s1
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n/an/an/an/a 100n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359195
PNG
(US10221129, Example JB-6)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)N(C)c1ccccc1Cl |r|
Show InChI InChI=1S/C25H27ClN4O5S/c1-29(19-13-15-20(35-3)16-14-19)24(31)22(17-18-9-5-4-6-10-18)27-25(32)28-36(33,34)30(2)23-12-8-7-11-21(23)26/h4-16,22H,17H2,1-3H3,(H2,27,28,32)/t22-/m0/s1
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n/an/an/an/a 660n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359199
PNG
(US10221129, Example JB-9)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)n1c2ccccc2c2ccccc12 |r|
Show InChI InChI=1S/C30H28N4O5S/c1-33(22-16-18-23(39-2)19-17-22)29(35)26(20-21-10-4-3-5-11-21)31-30(36)32-40(37,38)34-27-14-8-6-12-24(27)25-13-7-9-15-28(25)34/h3-19,26H,20H2,1-2H3,(H2,31,32,36)/t26-/m0/s1
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n/an/an/an/a 440n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359200
PNG
(US10221129, Example JB-11)
Show SMILES CN(C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)N(C)c1ccccc1Cl)c1ccc2ncccc2c1 |r|
Show InChI InChI=1S/C27H26ClN5O4S/c1-32(21-14-15-23-20(18-21)11-8-16-29-23)26(34)24(17-19-9-4-3-5-10-19)30-27(35)31-38(36,37)33(2)25-13-7-6-12-22(25)28/h3-16,18,24H,17H2,1-2H3,(H2,30,31,35)/t24-/m0/s1
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n/an/an/an/a 40n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359217
PNG
(US10221129, Example JB-27)
Show SMILES COc1ccc(NS(=O)(=O)NC(=O)N[C@@H](Cc2ccccc2)C(=O)N(C)c2ccc(OC)cc2)cc1 |r|
Show InChI InChI=1S/C25H28N4O6S/c1-29(20-11-15-22(35-3)16-12-20)24(30)23(17-18-7-5-4-6-8-18)26-25(31)28-36(32,33)27-19-9-13-21(34-2)14-10-19/h4-16,23,27H,17H2,1-3H3,(H2,26,28,31)/t23-/m0/s1
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n/an/an/an/a 150n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359222
PNG
(US10221129, Example JB-32)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1nccc2ccccc12 |r|
Show InChI InChI=1S/C27H27N5O5S/c1-32(21-12-14-22(37-2)15-13-21)26(33)24(18-19-8-4-3-5-9-19)29-27(34)31-38(35,36)30-25-23-11-7-6-10-20(23)16-17-28-25/h3-17,24H,18H2,1-2H3,(H,28,30)(H2,29,31,34)/t24-/m0/s1
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n/an/an/an/a 1.45E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359223
PNG
(US10221129, Example JB-33)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)NCCc1ccccc1 |r|
Show InChI InChI=1S/C26H30N4O5S/c1-30(22-13-15-23(35-2)16-14-22)25(31)24(19-21-11-7-4-8-12-21)28-26(32)29-36(33,34)27-18-17-20-9-5-3-6-10-20/h3-16,24,27H,17-19H2,1-2H3,(H2,28,29,32)/t24-/m0/s1
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n/an/an/an/a 680n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359236
PNG
(US10221129, Example JB-46)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1cc(F)cc(F)c1 |r|
Show InChI InChI=1S/C24H24F2N4O5S/c1-30(20-8-10-21(35-2)11-9-20)23(31)22(12-16-6-4-3-5-7-16)27-24(32)29-36(33,34)28-19-14-17(25)13-18(26)15-19/h3-11,13-15,22,28H,12H2,1-2H3,(H2,27,29,32)/t22-/m0/s1
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n/an/an/an/a 80n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359242
PNG
(US10221129, Example JB-52)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1ccc(NC(=O)N(C)C)cc1 |r|
Show InChI InChI=1S/C27H32N6O6S/c1-32(2)27(36)28-20-10-12-21(13-11-20)30-40(37,38)31-26(35)29-24(18-19-8-6-5-7-9-19)25(34)33(3)22-14-16-23(39-4)17-15-22/h5-17,24,30H,18H2,1-4H3,(H,28,36)(H2,29,31,35)/t24-/m0/s1
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n/an/an/an/a 5.94E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359243
PNG
(US10221129, Example JB-53)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)N1CCCCC1c1ccccc1 |r|
Show InChI InChI=1S/C29H34N4O5S/c1-32(24-16-18-25(38-2)19-17-24)28(34)26(21-22-11-5-3-6-12-22)30-29(35)31-39(36,37)33-20-10-9-15-27(33)23-13-7-4-8-14-23/h3-8,11-14,16-19,26-27H,9-10,15,20-21H2,1-2H3,(H2,30,31,35)/t26-,27?/m0/s1
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n/an/an/an/a 1.10E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM359246
PNG
(US10221129, Example JB-56)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)NCc1ccccc1 |r|
Show InChI InChI=1S/C25H28N4O5S/c1-29(21-13-15-22(34-2)16-14-21)24(30)23(17-19-9-5-3-6-10-19)27-25(31)28-35(32,33)26-18-20-11-7-4-8-12-20/h3-16,23,26H,17-18H2,1-2H3,(H2,27,28,31)/t23-/m0/s1
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n/an/an/an/a 1.87E+3n/an/an/an/a



VIIV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...

US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%