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USPatent US8772323

Compile Data Set for Download or QSAR

Found 260 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180438
PNG
(US8772323, 2)
Show SMILES C[C@H]1CC(=NNC1=O)c1ccc2nc(oc2c1)-c1ccccc1 |r,c:3|
Show InChI InChI=1S/C18H15N3O2/c1-11-9-15(20-21-17(11)22)13-7-8-14-16(10-13)23-18(19-14)12-5-3-2-4-6-12/h2-8,10-11H,9H2,1H3,(H,21,22)/t11-/m0/s1
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US Patent
n/an/an/an/a 787n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180452
PNG
(US8772323, 16)
Show SMILES O=C1CCC(=NN1)c1ccc2nc(oc2c1)-c1ccccc1 |c:4|
Show InChI InChI=1S/C17H13N3O2/c21-16-9-8-13(19-20-16)12-6-7-14-15(10-12)22-17(18-14)11-4-2-1-3-5-11/h1-7,10H,8-9H2,(H,20,21)
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US Patent
n/an/an/an/a 314n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180459
PNG
(US8772323, 23)
Show SMILES CC(C)(C)OC(=O)N1CCN(Cc2ccc(cc2)-c2nc3ccc(cc3o2)C2=NNC(=O)C3CC23)CC1 |t:30|
Show InChI InChI=1S/C28H31N5O4/c1-28(2,3)37-27(35)33-12-10-32(11-13-33)16-17-4-6-18(7-5-17)26-29-22-9-8-19(14-23(22)36-26)24-20-15-21(20)25(34)31-30-24/h4-9,14,20-21H,10-13,15-16H2,1-3H3,(H,31,34)
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US Patent
n/an/an/an/a 1.35E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180482
PNG
(US8772323, 44)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OCCN2CCN(C)CC2)cc1 |c:7|
Show InChI InChI=1S/C26H31N5O3/c1-3-18-17-24(32)28-29-25(18)20-6-9-22-23(16-20)34-26(27-22)19-4-7-21(8-5-19)33-15-14-31-12-10-30(2)11-13-31/h4-9,16,18H,3,10-15,17H2,1-2H3,(H,28,32)
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US Patent
n/an/an/an/a 1.09E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180487
PNG
(US8772323, 49)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OCCN2CCCCC2)cc1 |c:7|
Show InChI InChI=1S/C26H30N4O3/c1-2-18-17-24(31)28-29-25(18)20-8-11-22-23(16-20)33-26(27-22)19-6-9-21(10-7-19)32-15-14-30-12-4-3-5-13-30/h6-11,16,18H,2-5,12-15,17H2,1H3,(H,28,31)
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US Patent
n/an/an/an/a 114n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180489
PNG
(US8772323, 51)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OCc2cccs2)cc1 |c:7|
Show InChI InChI=1S/C24H21N3O3S/c1-2-15-13-22(28)26-27-23(15)17-7-10-20-21(12-17)30-24(25-20)16-5-8-18(9-6-16)29-14-19-4-3-11-31-19/h3-12,15H,2,13-14H2,1H3,(H,26,28)
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n/an/an/an/a 158n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180504
PNG
(US8772323, 66)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OCC(=O)OC(C)(C)C)cc1 |c:7|
Show InChI InChI=1S/C25H27N3O5/c1-5-15-13-21(29)27-28-23(15)17-8-11-19-20(12-17)32-24(26-19)16-6-9-18(10-7-16)31-14-22(30)33-25(2,3)4/h6-12,15H,5,13-14H2,1-4H3,(H,27,29)
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US Patent
n/an/an/an/a 112n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180551
PNG
(US8772323, 78)
Show SMILES CCC1OC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccccc1 |c:7|
Show InChI InChI=1S/C18H15N3O3/c1-2-14-16(20-21-18(22)24-14)12-8-9-13-15(10-12)23-17(19-13)11-6-4-3-5-7-11/h3-10,14H,2H2,1H3,(H,21,22)
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n/an/an/an/a 61n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180556
PNG
(US8772323, 83)
Show SMILES COc1ccc(cc1)-c1nc2ccc(cc2o1)C1=NNC(=O)CC1C |t:20|
Show InChI InChI=1S/C19H17N3O3/c1-11-9-17(23)21-22-18(11)13-5-8-15-16(10-13)25-19(20-15)12-3-6-14(24-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,21,23)
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n/an/an/an/a 94n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180557
PNG
(US8772323, 84)
Show SMILES CC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(Cl)cc1 |c:6|
Show InChI InChI=1S/C18H14ClN3O2/c1-10-8-16(23)21-22-17(10)12-4-7-14-15(9-12)24-18(20-14)11-2-5-13(19)6-3-11/h2-7,9-10H,8H2,1H3,(H,21,23)
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US Patent
n/an/an/an/a 132n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180605
PNG
(US8772323, 106)
Show SMILES CC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1cccs1 |c:6|
Show InChI InChI=1S/C16H13N3O2S/c1-9-7-14(20)18-19-15(9)10-4-5-11-12(8-10)21-16(17-11)13-3-2-6-22-13/h2-6,8-9H,7H2,1H3,(H,18,20)
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US Patent
n/an/an/an/a 120n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180608
PNG
(US8772323, 109)
Show SMILES CC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(N)nc1 |c:6|
Show InChI InChI=1S/C17H15N5O2/c1-9-6-15(23)21-22-16(9)10-2-4-12-13(7-10)24-17(20-12)11-3-5-14(18)19-8-11/h2-5,7-9H,6H2,1H3,(H2,18,19)(H,21,23)
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US Patent
n/an/an/an/a 1.41E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180611
PNG
(US8772323, 112)
Show SMILES O=C1CCC(=NN1)c1ccc2nc(oc2c1)-c1ccco1 |c:4|
Show InChI InChI=1S/C15H11N3O3/c19-14-6-5-10(17-18-14)9-3-4-11-13(8-9)21-15(16-11)12-2-1-7-20-12/h1-4,7-8H,5-6H2,(H,18,19)
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n/an/an/an/a 1.32E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180623
PNG
(US8772323, 124)
Show SMILES CC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(CN)cc1 |c:6|
Show InChI InChI=1S/C19H18N4O2/c1-11-8-17(24)22-23-18(11)14-6-7-15-16(9-14)25-19(21-15)13-4-2-12(10-20)3-5-13/h2-7,9,11H,8,10,20H2,1H3,(H,22,24)
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n/an/an/an/a 8.72E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180626
PNG
(US8772323, 127)
Show SMILES CC[C@@H]1[C@H](C)C(=NNC1=O)c1ccc2nc(oc2c1)-c1ccccc1 |r,c:5|
Show InChI InChI=1S/C20H19N3O2/c1-3-15-12(2)18(22-23-19(15)24)14-9-10-16-17(11-14)25-20(21-16)13-7-5-4-6-8-13/h4-12,15H,3H2,1-2H3,(H,23,24)/t12-,15+/m0/s1
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n/an/an/an/a 2.59E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180635
PNG
(US8772323, 134)
Show SMILES O=C1NN=C([C@@H]2C[C@H]12)[C@@H]1CCc2nc(oc2C1)-c1ccccc1 |r,c:3|
Show InChI InChI=1S/C18H17N3O2/c22-17-13-9-12(13)16(20-21-17)11-6-7-14-15(8-11)23-18(19-14)10-4-2-1-3-5-10/h1-5,11-13H,6-9H2,(H,21,22)/t11-,12-,13+/m1/s1
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n/an/an/an/a 1.63E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180509
PNG
(US8772323, 148)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1cccc(OCCN2CCCCC2)c1 |c:7|
Show InChI InChI=1S/C26H30N4O3/c1-2-18-17-24(31)28-29-25(18)19-9-10-22-23(16-19)33-26(27-22)20-7-6-8-21(15-20)32-14-13-30-11-4-3-5-12-30/h6-10,15-16,18H,2-5,11-14,17H2,1H3,(H,28,31)
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n/an/an/an/a 1.56E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180514
PNG
(US8772323, 153)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1cccc(OCCN2CCC(CC2)C#N)c1 |c:7|
Show InChI InChI=1S/C27H29N5O3/c1-2-19-16-25(33)30-31-26(19)20-6-7-23-24(15-20)35-27(29-23)21-4-3-5-22(14-21)34-13-12-32-10-8-18(17-28)9-11-32/h3-7,14-15,18-19H,2,8-13,16H2,1H3,(H,30,33)
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US Patent
n/an/an/an/a 735n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180521
PNG
(US8772323, 160)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OCCN(CC(C)C)CC(C)C)cc1 |c:7|
Show InChI InChI=1S/C29H38N4O3/c1-6-21-16-27(34)31-32-28(21)23-9-12-25-26(15-23)36-29(30-25)22-7-10-24(11-8-22)35-14-13-33(17-19(2)3)18-20(4)5/h7-12,15,19-21H,6,13-14,16-18H2,1-5H3,(H,31,34)
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n/an/an/an/a 124n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180526
PNG
(US8772323, 165)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OCCN2CCN(CC2)C(=O)OC(C)(C)C)cc1 |c:7|
Show InChI InChI=1S/C30H37N5O5/c1-5-20-19-26(36)32-33-27(20)22-8-11-24-25(18-22)39-28(31-24)21-6-9-23(10-7-21)38-17-16-34-12-14-35(15-13-34)29(37)40-30(2,3)4/h6-11,18,20H,5,12-17,19H2,1-4H3,(H,32,36)
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US Patent
n/an/an/an/a 118n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180530
PNG
(US8772323, 169)
Show SMILES CCC[C@@H]1[C@H](C)C(=NNC1=O)c1ccc2nc(oc2c1)-c1ccc(OCCN(C(C)C)C(C)C)cc1 |r,c:6|
Show InChI InChI=1S/C29H38N4O3/c1-7-8-24-20(6)27(31-32-28(24)34)22-11-14-25-26(17-22)36-29(30-25)21-9-12-23(13-10-21)35-16-15-33(18(2)3)19(4)5/h9-14,17-20,24H,7-8,15-16H2,1-6H3,(H,32,34)/t20-,24+/m0/s1
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n/an/an/an/a 1.04E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180586
PNG
(US8772323, 176)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OC2CCCC2)cc1 |c:7|
Show InChI InChI=1S/C24H25N3O3/c1-2-15-14-22(28)26-27-23(15)17-9-12-20-21(13-17)30-24(25-20)16-7-10-19(11-8-16)29-18-5-3-4-6-18/h7-13,15,18H,2-6,14H2,1H3,(H,26,28)
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n/an/an/an/a 82n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180588
PNG
(US8772323, 178 | US8772323, 208)
Show SMILES CC[C@@H]1[C@@H](C)C(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OC(C)C)cc1 |r,c:8|
Show InChI InChI=1S/C23H25N3O3/c1-5-18-14(4)22(27)26-25-21(18)16-8-11-19-20(12-16)29-23(24-19)15-6-9-17(10-7-15)28-13(2)3/h6-14,18H,5H2,1-4H3,(H,26,27)/t14-,18-/m1/s1
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n/an/an/an/a 108n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180595
PNG
(US8772323, 185)
Show SMILES CCC[C@@H]1[C@@H](C)C(=NNC1=O)c1ccc2nc(oc2c1)-c1ccc(Cl)cc1 |r,c:6|
Show InChI InChI=1S/C21H20ClN3O2/c1-3-4-16-12(2)19(24-25-20(16)26)14-7-10-17-18(11-14)27-21(23-17)13-5-8-15(22)9-6-13/h5-12,16H,3-4H2,1-2H3,(H,25,26)/t12-,16-/m1/s1
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n/an/an/an/a 142n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180596
PNG
(US8772323, 186)
Show SMILES CCC[C@@H]1[C@@H](C)C(=NNC1=O)c1ccc2nc(oc2c1)-c1cc(C)cs1 |r,c:6|
Show InChI InChI=1S/C20H21N3O2S/c1-4-5-14-12(3)18(22-23-19(14)24)13-6-7-15-16(9-13)25-20(21-15)17-8-11(2)10-26-17/h6-10,12,14H,4-5H2,1-3H3,(H,23,24)/t12-,14-/m1/s1
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n/an/an/an/a 88n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180579
PNG
(US8772323, 190)
Show SMILES CC[C@@H]1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OC)cc1 |r,c:7|
Show InChI InChI=1S/C20H19N3O3/c1-3-12-11-18(24)22-23-19(12)14-6-9-16-17(10-14)26-20(21-16)13-4-7-15(25-2)8-5-13/h4-10,12H,3,11H2,1-2H3,(H,22,24)/t12-/m1/s1
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n/an/an/an/a 79n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180580
PNG
(US8772323, 191)
Show SMILES CC[C@@H]1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(cc1)N(C)C |r,c:7|
Show InChI InChI=1S/C21H22N4O2/c1-4-13-12-19(26)23-24-20(13)15-7-10-17-18(11-15)27-21(22-17)14-5-8-16(9-6-14)25(2)3/h5-11,13H,4,12H2,1-3H3,(H,23,26)/t13-/m1/s1
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n/an/an/an/a 41n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180665
PNG
(US8772323, 222)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OCCN(CC)CC)cc1 |c:7|
Show InChI InChI=1S/C25H30N4O3/c1-4-17-16-23(30)27-28-24(17)19-9-12-21-22(15-19)32-25(26-21)18-7-10-20(11-8-18)31-14-13-29(5-2)6-3/h7-12,15,17H,4-6,13-14,16H2,1-3H3,(H,27,30)
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n/an/an/an/a 299n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180669
PNG
(US8772323, 226)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OC[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1 |r,c:7|
Show InChI InChI=1S/C29H34N4O5/c1-5-18-16-25(34)31-32-26(18)20-10-13-23-24(15-20)37-27(30-23)19-8-11-22(12-9-19)36-17-21-7-6-14-33(21)28(35)38-29(2,3)4/h8-13,15,18,21H,5-7,14,16-17H2,1-4H3,(H,31,34)/t18?,21-/m0/s1
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n/an/an/an/a 47n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180670
PNG
(US8772323, 227)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OC[C@H]2CCCN2C(=O)OC(C)(C)C)cc1 |r,c:7|
Show InChI InChI=1S/C29H34N4O5/c1-5-18-16-25(34)31-32-26(18)20-10-13-23-24(15-20)37-27(30-23)19-8-11-22(12-9-19)36-17-21-7-6-14-33(21)28(35)38-29(2,3)4/h8-13,15,18,21H,5-7,14,16-17H2,1-4H3,(H,31,34)/t18?,21-/m1/s1
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n/an/an/an/a 52n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180677
PNG
(US8772323, 234)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OC2CCCCCN2C)cc1 |c:7|
Show InChI InChI=1S/C26H30N4O3/c1-3-17-16-23(31)28-29-25(17)19-10-13-21-22(15-19)33-26(27-21)18-8-11-20(12-9-18)32-24-7-5-4-6-14-30(24)2/h8-13,15,17,24H,3-7,14,16H2,1-2H3,(H,28,31)
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n/an/an/an/a 306n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180678
PNG
(US8772323, 235)
Show SMILES CC[C@@H]1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OC(C)CN2CCCCC2)cc1 |r,c:7|
Show InChI InChI=1S/C27H32N4O3/c1-3-19-16-25(32)29-30-26(19)21-9-12-23-24(15-21)34-27(28-23)20-7-10-22(11-8-20)33-18(2)17-31-13-5-4-6-14-31/h7-12,15,18-19H,3-6,13-14,16-17H2,1-2H3,(H,29,32)/t18?,19-/m1/s1
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n/an/an/an/a 104n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180454
PNG
(US8772323, 18)
Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2o1)C1=NNC(=O)C2CC12 |t:19|
Show InChI InChI=1S/C18H12FN3O2/c19-11-4-1-9(2-5-11)18-20-14-6-3-10(7-15(14)24-18)16-12-8-13(12)17(23)22-21-16/h1-7,12-13H,8H2,(H,22,23)
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n/an/an/an/a 153n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180472
PNG
(US8772323, 35)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1cccc(OCc2ccccc2)c1 |c:7|
Show InChI InChI=1S/C26H23N3O3/c1-2-18-15-24(30)28-29-25(18)19-11-12-22-23(14-19)32-26(27-22)20-9-6-10-21(13-20)31-16-17-7-4-3-5-8-17/h3-14,18H,2,15-16H2,1H3,(H,28,30)
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n/an/an/an/a 148n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180493
PNG
(US8772323, 55)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OCCN(C)C)cc1 |c:7|
Show InChI InChI=1S/C23H26N4O3/c1-4-15-14-21(28)25-26-22(15)17-7-10-19-20(13-17)30-23(24-19)16-5-8-18(9-6-16)29-12-11-27(2)3/h5-10,13,15H,4,11-12,14H2,1-3H3,(H,25,28)
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n/an/an/an/a 486n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180498
PNG
(US8772323, 60)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OCc2cccnc2)cc1 |c:7|
Show InChI InChI=1S/C25H22N4O3/c1-2-17-13-23(30)28-29-24(17)19-7-10-21-22(12-19)32-25(27-21)18-5-8-20(9-6-18)31-15-16-4-3-11-26-14-16/h3-12,14,17H,2,13,15H2,1H3,(H,28,30)
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n/an/an/an/a 639n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180502
PNG
(US8772323, 64)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OCCN2CCOCC2)cc1 |c:7|
Show InChI InChI=1S/C25H28N4O4/c1-2-17-16-23(30)27-28-24(17)19-5-8-21-22(15-19)33-25(26-21)18-3-6-20(7-4-18)32-14-11-29-9-12-31-13-10-29/h3-8,15,17H,2,9-14,16H2,1H3,(H,27,30)
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n/an/an/an/a 237n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180544
PNG
(US8772323, 71)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OCC2CCNCC2)cc1 |c:7|
Show InChI InChI=1S/C25H28N4O3/c1-2-17-14-23(30)28-29-24(17)19-5-8-21-22(13-19)32-25(27-21)18-3-6-20(7-4-18)31-15-16-9-11-26-12-10-16/h3-8,13,16-17,26H,2,9-12,14-15H2,1H3,(H,28,30)
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n/an/an/an/a>1.00E+4n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180546
PNG
(US8772323, 73)
Show SMILES CC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1cccc(OCC2CCNCC2)c1 |c:6|
Show InChI InChI=1S/C24H26N4O3/c1-15-11-22(29)27-28-23(15)17-5-6-20-21(13-17)31-24(26-20)18-3-2-4-19(12-18)30-14-16-7-9-25-10-8-16/h2-6,12-13,15-16,25H,7-11,14H2,1H3,(H,27,29)
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n/an/an/an/a 6.77E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180550
PNG
(US8772323, 77)
Show SMILES CCC1SC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccccc1 |c:7|
Show InChI InChI=1S/C18H15N3O2S/c1-2-15-16(20-21-18(22)24-15)12-8-9-13-14(10-12)23-17(19-13)11-6-4-3-5-7-11/h3-10,15H,2H2,1H3,(H,21,22)
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n/an/an/an/a 141n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180567
PNG
(US8772323, 94)
Show SMILES CCOc1ccc(cc1)-c1nc2ccc(cc2o1)C1=NNC(=O)CC1CC |t:21|
Show InChI InChI=1S/C21H21N3O3/c1-3-13-12-19(25)23-24-20(13)15-7-10-17-18(11-15)27-21(22-17)14-5-8-16(9-6-14)26-4-2/h5-11,13H,3-4,12H2,1-2H3,(H,23,25)
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n/an/an/an/a 114n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180570
PNG
(US8772323, 97)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1cc(C)cs1 |c:7|
Show InChI InChI=1S/C18H17N3O2S/c1-3-11-8-16(22)20-21-17(11)12-4-5-13-14(7-12)23-18(19-13)15-6-10(2)9-24-15/h4-7,9,11H,3,8H2,1-2H3,(H,20,22)
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n/an/an/an/a 225n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180571
PNG
(US8772323, 98)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OC)c(F)c1 |c:7|
Show InChI InChI=1S/C20H18FN3O3/c1-3-11-10-18(25)23-24-19(11)12-4-6-15-17(9-12)27-20(22-15)13-5-7-16(26-2)14(21)8-13/h4-9,11H,3,10H2,1-2H3,(H,23,25)
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n/an/an/an/a 294n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180612
PNG
(US8772323, 113)
Show SMILES CC1CC(=O)NN=C1c1ccc2nc(oc2c1)N1CCSCC1 |c:6|
Show InChI InChI=1S/C16H18N4O2S/c1-10-8-14(21)18-19-15(10)11-2-3-12-13(9-11)22-16(17-12)20-4-6-23-7-5-20/h2-3,9-10H,4-8H2,1H3,(H,18,21)
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n/an/an/an/a 1.90E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180614
PNG
(US8772323, 115)
Show SMILES CC1CC(=O)NN=C1c1ccc2nc(oc2c1)N1CCCCC1 |c:6|
Show InChI InChI=1S/C17H20N4O2/c1-11-9-15(22)19-20-16(11)12-5-6-13-14(10-12)23-17(18-13)21-7-3-2-4-8-21/h5-6,10-11H,2-4,7-9H2,1H3,(H,19,22)
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n/an/an/an/a 1.13E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180615
PNG
(US8772323, 116)
Show SMILES CC1CC(=O)NN=C1c1ccc2nc(oc2c1)N1CCOCC1 |c:6|
Show InChI InChI=1S/C16H18N4O3/c1-10-8-14(21)18-19-15(10)11-2-3-12-13(9-11)23-16(17-12)20-4-6-22-7-5-20/h2-3,9-10H,4-8H2,1H3,(H,18,21)
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n/an/an/an/a 3.45E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180625
PNG
(US8772323, 126)
Show SMILES CC[C@H]1[C@H](C)C(=NNC1=O)c1ccc2nc(oc2c1)-c1ccccc1 |r,c:5|
Show InChI InChI=1S/C20H19N3O2/c1-3-15-12(2)18(22-23-19(15)24)14-9-10-16-17(11-14)25-20(21-16)13-7-5-4-6-8-13/h4-12,15H,3H2,1-2H3,(H,23,24)/t12-,15-/m0/s1
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n/an/an/an/a 306n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180643
PNG
(US8772323, 141)
Show SMILES CCC1CC(=NNC1=O)c1ccc2nc(oc2c1)-c1cccs1 |c:4|
Show InChI InChI=1S/C17H15N3O2S/c1-2-10-8-13(19-20-16(10)21)11-5-6-12-14(9-11)22-17(18-12)15-4-3-7-23-15/h3-7,9-10H,2,8H2,1H3,(H,20,21)
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n/an/an/an/a 7.33E+3n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180645
PNG
(US8772323, 143)
Show SMILES O=C1NCC(=NN1)c1ccc2nc(oc2c1)-c1ccccc1 |c:4|
Show InChI InChI=1S/C16H12N4O2/c21-16-17-9-13(19-20-16)11-6-7-12-14(8-11)22-15(18-12)10-4-2-1-3-5-10/h1-8H,9H2,(H2,17,20,21)
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n/an/an/an/a 397n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))
BDBM180515
PNG
(US8772323, 154)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1cccc(OCCN(C(C)C)C(C)C)c1 |c:7|
Show InChI InChI=1S/C27H34N4O3/c1-6-19-16-25(32)29-30-26(19)20-10-11-23-24(15-20)34-27(28-23)21-8-7-9-22(14-21)33-13-12-31(17(2)3)18(4)5/h7-11,14-15,17-19H,6,12-13,16H2,1-5H3,(H,29,32)
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n/an/an/an/a 424n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%