| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bromodomain-containing protein 3 [311-412] |
|---|
| Ligand | BDBM528580 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Binding Assay |
|---|
| IC50 | 29.0±n/a nM |
|---|
| Citation |  Pham, SM; Chakravarty, S; Kankanala, J; Chen, J; Nayak, AK; Barde, A Substituted 1,6-dihydropyridinones and 1,2-dihydroisoquinolinones as bet inhibitors US Patent US11192900 Publication Date 12/7/2021 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Bromodomain-containing protein 3 [311-412] |
|---|
| Name: | Bromodomain-containing protein 3 [311-412] |
|---|
| Synonyms: | BRD3 | BRD3-2 | BRD3_HUMAN | Bromodomain-containing protein 3 (BD2, aa 311-412) | KIAA0043 | RING3L |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 12125.83 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q15059[311-412] |
|---|
| Residue: | 102 |
|---|
| Sequence: | HLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREY
PDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF
|
|
|
|---|
| BDBM528580 |
|---|
| n/a |
|---|
| Name | BDBM528580 |
|---|
| Synonyms: | US11192900, Compound 3 | US11192900, Example S-10 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H19F2N3O4S |
|---|
| Mol. Mass. | 447.455 |
|---|
| SMILES | CNc1cc(cn(C)c1=O)-c1cc(NS(=O)(=O)C=C)ccc1Oc1ccc(F)cc1F |
|---|
| Structure | 
|
|---|
Search and Browse
