| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-C chemokine receptor type 6 |
|---|
| Ligand | BDBM531124 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Biological Assay |
|---|
| IC50 | 17.0±n/a nM |
|---|
| Citation |  Hein, CD; Duong, TT; Sinha, S; Li, L; Nguyen, JH; Old, DW; Burk, R; Viswanath, V; Rao, S; Donello, JE 3,4-disubstituted 3-cyclobutene-1,2-diones and use thereof US Patent US11208377 Publication Date 12/28/2021 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-C chemokine receptor type 6 |
|---|
| Name: | C-C chemokine receptor type 6 |
|---|
| Synonyms: | C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 42510.84 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P51684 |
|---|
| Residue: | 374 |
|---|
| Sequence: | MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
SETADNDNASSFTM
|
|
|
|---|
| BDBM531124 |
|---|
| n/a |
|---|
| Name | BDBM531124 |
|---|
| Synonyms: | 3-((2-((5,5-dimethyl-4,5,6,7-tetrahydrobenzofuran-4-yl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)-2-hydroxy-N,N-dimethylbenzamide | US11208377, Compound 28 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H25N3O5 |
|---|
| Mol. Mass. | 423.4617 |
|---|
| SMILES | CN(C)C(=O)c1cccc(Nc2c(NC3c4ccoc4CCC3(C)C)c(=O)c2=O)c1O |
|---|
| Structure | 
|
|---|
Search and Browse
