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TargetC-C chemokine receptor type 6
LigandBDBM531160
Substrate/Competitorn/a
Meas. Tech.Biological Assay
IC50 25.0±n/a nM
Citation Hein, CDDuong, TTSinha, SLi, LNguyen, JHOld, DWBurk, RViswanath, VRao, SDonello, JE 3,4-disubstituted 3-cyclobutene-1,2-diones and use thereof US Patent US11208377 Publication Date 12/28/2021
More Info.:Get all data from this article,  Assay Method
 
C-C chemokine receptor type 6
Name:C-C chemokine receptor type 6
Synonyms:C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:Enzyme
Mol. Mass.:42510.84
Organism:Homo sapiens (Human)
Description:P51684
Residue:374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
SETADNDNASSFTM
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  Blast E-value cutoff:
BDBM531160
n/a
NameBDBM531160
Synonyms:6-chloro-3-((2-((2,2-dimethylcyclohexyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)-2-hydroxy-N,N-dimethylbenzenesulfonamide | US11208377, Compound 64
TypeSmall organic molecule
Emp. Form.C20H26ClN3O5S
Mol. Mass.455.956
SMILESCN(C)S(=O)(=O)c1c(Cl)ccc(Nc2c(NC3CCCCC3(C)C)c(=O)c2=O)c1O
Structure
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