Reaction Details | |||
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Target | Induced myeloid leukemia cell differentiation protein Mcl-1 | ||
Ligand | BDBM429164 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Bak Peptide Binding Assay | ||
Ki | <50.0±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Induced myeloid leukemia cell differentiation protein Mcl-1 | |||
Name: | Induced myeloid leukemia cell differentiation protein Mcl-1 | ||
Synonyms: | BCL2L3 | Bcl-2-like protein 3 | Bcl-2-like protein 3 (Mcl-1) | Bcl-2-related protein EAT/mcl1 | Bcl2-L-3 | Induced myeloid leukemia cell differentiation protein (Mcl-1) | MCL1 | MCL1_HUMAN | Mcl-1 | Myeloid Cell factor-1 (Mcl-1) | Myeloid cell leukemia sequence 1 (BCL2-related) | mcl1/EAT | ||
Type: | Membrane; Single-pass membrane protein | ||
Mol. Mass.: | 37332.87 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q07820 | ||
Residue: | 350 | ||
Sequence: |
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BDBM429164 | |||
n/a | |||
Name | BDBM429164 | ||
Synonyms: | US10533010, Example I-286 | US11208415, Example I-286 | ||
Type | Small organic molecule | ||
Emp. Form. | C28H31ClN4O4 | ||
Mol. Mass. | 523.023 | ||
SMILES | Cc1nn(C)c(C)c1-c1cccc2c(CCCOc3cc(C)c(Cl)c(C)c3)c([nH]c12)C(=O)NCC(O)=O |(-1.3,5.31,;-2.64,6.08,;-3.11,7.54,;-4.65,7.54,;-5.42,8.88,;-5.13,6.08,;-6.46,5.31,;-3.88,5.17,;-3.88,3.63,;-5.22,2.86,;-5.22,1.32,;-3.88,.55,;-2.55,1.32,;-1.08,.85,;-.68,-.64,;.8,-1.04,;1.2,-2.53,;2.69,-2.93,;3.09,-4.41,;4.58,-4.81,;4.97,-6.3,;6.46,-6.7,;3.88,-7.39,;4.28,-8.88,;2.4,-6.99,;1.31,-8.08,;2,-5.5,;-.18,2.09,;-1.08,3.34,;-2.55,2.86,;1.36,2.09,;2.13,.76,;2.13,3.43,;3.67,3.43,;4.44,4.76,;5.98,4.76,;3.67,6.09,)| | ||
Structure | ![]() |