| Reaction Details |
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 | Report a problem with these data |
| Target | Arginase-2, mitochondrial |
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| Ligand | BDBM568462 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biological Activity of Examples 1 to 30 |
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| IC50 | 850±n/a nM |
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| Citation |  Mlynarski, SN; Grebe, T; Kawatkar, S; Finlay, MR; Simpson, I; Wang, J; Cook, S; Wu, D Arginase inhibitors and methods of use thereof US Patent US11420984 Publication Date 8/23/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Arginase-2, mitochondrial |
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| Name: | Arginase-2, mitochondrial |
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| Synonyms: | ARG2 | ARGI2_HUMAN | Arginase II | Kidney-type arginase | Non-hepatic arginase | Type II arginase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38576.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_978892 |
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| Residue: | 354 |
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| Sequence: | MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDH
SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG
FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG
KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ
LATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
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| BDBM568462 |
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| n/a |
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| Name | BDBM568462 |
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| Synonyms: | US11420984, Example 12 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H26BN3O5 |
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| Mol. Mass. | 327.184 |
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| SMILES | OB(O)CCCC[C@@]1(C[C@H](CN1)NC(=O)[C@@H]1CCCN1)C(O)=O |r,$;;;;;;;;;;;N;;;;;;;;;;;$| |
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| Structure | 
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