| Reaction Details |
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 | Report a problem with these data |
| Target | Enteropeptidase |
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| Ligand | BDBM571800 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enteropeptidase Inhibition Assay |
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| Ki | 3.00±n/a nM |
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| Citation |  Kim, YK; Kwon, O; Park, H; Park, J; Choi, HG; Son, JB; Ko, E; Kim, SY; Lee, S; Kang, SY; Ko, YK; Park, J Compound exhibiting enteropeptidase inhibitory activity US Patent US11447480 Publication Date 9/20/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Enteropeptidase |
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| Name: | Enteropeptidase |
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| Synonyms: | ENTK | ENTK_HUMAN | PRSS7 | TMPRSS15 |
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| Type: | Enzyme |
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| Mol. Mass.: | 112901.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P98073 |
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| Residue: | 1019 |
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| Sequence: | MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARA
TFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSII
VVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNV
SIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQA
THYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETN
PGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDL
NDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEP
ACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFN
AFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSST
NFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPG
PVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVN
LCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLG
LGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQD
ITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAI
LGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEE
NQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYE
EGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH
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| BDBM571800 |
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| n/a |
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| Name | BDBM571800 |
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| Synonyms: | 4-Carbamimidoyl-2-fluorophenyl 2-((4-methoxy-4-oxobutyl)(methyl)amino)thiazole-5-carboxylate | US11447480, Example 21 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19FN4O4S |
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| Mol. Mass. | 394.421 |
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| SMILES | COC(=O)CCCN(C)c1ncc(s1)C(=O)Oc1ccc(cc1F)C(N)=N |
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| Structure | 
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