| Reaction Details |
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 | Report a problem with these data |
| Target | Transmembrane anterior posterior transformation protein 1 homolog |
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| Ligand | BDBM575093 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Assessing Antiviral Activity Against Human Cytomegalovirus (HCMV) |
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| IC50 | 956±n/a nM |
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| Citation |  Remiszewski, S; Chiang, LW; Murphy, EA; Sun, Q; Kayser, F; Fink, SJ Broad spectrum antiviral compositions and methods US Patent US11459321 Publication Date 10/4/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Transmembrane anterior posterior transformation protein 1 homolog |
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| Name: | Transmembrane anterior posterior transformation protein 1 homolog |
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| Synonyms: | CMVFR | Cytomegalovirus partial fusion receptor | TAPT1 | TAPT1_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 64270.48 |
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| Organism: | Human |
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| Description: | Q6NXT6 |
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| Residue: | 567 |
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| Sequence: | MAGVGDAAAPGEGGGGGVDGPQRDGRGEAEQPGGSGGQGPPPAPQLTETLGFYESDRRRE
RRRGRTELSLLRFLSAELTRGYFLEHNEAKYTERRERVYTCLRIPRELEKLMVFGIFLCL
DAFLYVFTLLPLRVFLALFRLLTLPCYGLRDRRLLQPAQVCDILKGVILVICYFMMHYVD
YSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIP
HFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLF
QMSNSDIKERFTNYVLLLIVCLRNMEQFSWNPDHLWVLFPDVCMVIASEIAVDIVKHAFI
TKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVARRMGFIPLPLAVLLIRVVTSS
IKVQGILSYACVILFYFGLISLKVLNSIVLLGKSCQYVKEAKMEEKLSNPPATCTPGKPS
SKSQNKCKPSQGLSTEENLSASITKQPIHQKENIIPLLVTSNSDQFLTTPDGDEKDITQD
NSELKHRSSKKDLLEIDRFTICGNRID
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| BDBM575093 |
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| n/a |
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| Name | BDBM575093 |
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| Synonyms: | US11459321, Example 40 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H24N4O4S |
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| Mol. Mass. | 476.547 |
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| SMILES | O=C1OCCN1c1cccc(Cc2cnc(s2)N2CCc3ccc(cc3C2)N2CCOC2=O)c1 |
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| Structure | 
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