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TargetTransmembrane anterior posterior transformation protein 1 homolog
LigandBDBM575122
Substrate/Competitorn/a
Meas. Tech.Assessing Antiviral Activity Against Human Cytomegalovirus (HCMV)
IC50 730±n/a nM
Citation Remiszewski, SChiang, LWMurphy, EASun, QKayser, FFink, SJ Broad spectrum antiviral compositions and methods US Patent US11459321 Publication Date 10/4/2022
More Info.:Get all data from this article,  Assay Method
 
Transmembrane anterior posterior transformation protein 1 homolog
Name:Transmembrane anterior posterior transformation protein 1 homolog
Synonyms:CMVFR | Cytomegalovirus partial fusion receptor | TAPT1 | TAPT1_HUMAN
Type:Protein
Mol. Mass.:64270.48
Organism:Human
Description:Q6NXT6
Residue:567
Sequence:
MAGVGDAAAPGEGGGGGVDGPQRDGRGEAEQPGGSGGQGPPPAPQLTETLGFYESDRRRE
RRRGRTELSLLRFLSAELTRGYFLEHNEAKYTERRERVYTCLRIPRELEKLMVFGIFLCL
DAFLYVFTLLPLRVFLALFRLLTLPCYGLRDRRLLQPAQVCDILKGVILVICYFMMHYVD
YSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIP
HFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLF
QMSNSDIKERFTNYVLLLIVCLRNMEQFSWNPDHLWVLFPDVCMVIASEIAVDIVKHAFI
TKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVARRMGFIPLPLAVLLIRVVTSS
IKVQGILSYACVILFYFGLISLKVLNSIVLLGKSCQYVKEAKMEEKLSNPPATCTPGKPS
SKSQNKCKPSQGLSTEENLSASITKQPIHQKENIIPLLVTSNSDQFLTTPDGDEKDITQD
NSELKHRSSKKDLLEIDRFTICGNRID
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM575122
n/a
NameBDBM575122
Synonyms:US11459321, Example 59
TypeSmall organic molecule
Emp. Form.C29H34N4O2S
Mol. Mass.502.671
SMILESCN1CCCN(C1=O)c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)C2CCOCC2)s1
Structure
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