| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Coagulation factor XIII A chain |
|---|
| Ligand | BDBM577487 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Isopeptidase Assay for Estimating Inhibitor Potency |
|---|
| IC50 | 13.0±n/a nM |
|---|
| Citation |  Hils, M; Pasternack, R; Büchold, C Inhibitors of blood coagulation factor XIII US Patent US11472838 Publication Date 10/18/2022 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Coagulation factor XIII A chain |
|---|
| Name: | Coagulation factor XIII A chain |
|---|
| Synonyms: | Coagulation factor XIII | F13A | F13A1 | F13A_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 83261.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1475048 |
|---|
| Residue: | 732 |
|---|
| Sequence: | MSETSRTAFGGRRAVPPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDT
NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPV
PIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETD
TYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCL
YVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDIL
LEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGN
VNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKH
GHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMMDITD
TYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKLSITF
RNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLL
EQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVQFTNPLKET
LRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYG
ELDVQIQRRPSM
|
|
|
|---|
| BDBM577487 |
|---|
| n/a |
|---|
| Name | BDBM577487 |
|---|
| Synonyms: | US11472838, Compound 4 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C43H59N7O13 |
|---|
| Mol. Mass. | 881.9677 |
|---|
| SMILES | COC(=O)\C=C\CC[C@H](NC(=O)c1cc(cc(c1)[N+]([O-])=O)C(O)=O)C(=O)N[C@H](C(=O)N1CC(=O)C[C@H]1C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@@H](C1CCCCC1)C(N)=O)C(C)(C)C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
