Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50318713 ((2S,15S,18S,21S,24S)-15-(3-amino-3-oxopropyl)-2-be...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50318712 ((2S,15S,18S,21S,24S)-15-(2-amino-2-oxoethyl)-2-ben...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314131 ((S,E)-Ethyl 4-((R)-2-(tert-Butoxycarbonylamino)-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314126 ((S)-Benzyl-2-[(Z)-3-((S)-1-benzyloxycarbonyl-2-phe...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50318710 ((2S,15S,18S,21S,24S)-2,15-dibenzyl-24-carbamoyl-18...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using low concentration of enzyme by standard fluorescence assay in presence of de... | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50318714 ((2S,15S,18S,21S,24S)-15-(acetamidomethyl)-2-benzyl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314130 ((S)-2-[(E)-3-((S)-1-Benzyloxycarbonyl-2-phenylethy...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using high concentration of enzyme by standard fluorescence assay in presence of d... | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50318711 ((2S,15S,18S,21S,24S)-15-(2-amino-2-oxoethyl)-2-ben...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using low concentration of enzyme by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314125 ((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using high concentration of enzyme by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50318715 ((2S,15S,18S,21S,24S)-2-benzyl-24-carbamoyl-18,21-d...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50318716 ((2S,8S,15S,18S,21S,24S)-2-benzyl-24-carbamoyl-18,2...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314127 ((S)-Benzyl-2-{(Z)-3-[(S)-1-((S)-1-benzyloxycarbony...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314128 ((S,E)-Methyl 2-(4-Ethoxy-4-oxobut-2-enamido)-5-oxo...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50318712 ((2S,15S,18S,21S,24S)-15-(2-amino-2-oxoethyl)-2-ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of human liver cathepsin B | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50318717 ((2S,15S,18S,21S,24S)-15-(acetamidomethyl)-2-benzyl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50318709 ((2S,15S,18S,21S,24S)-15-(2-amino-2-oxoethyl)-2-ben...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314124 ((S,E)-ethyl 4-(tert-butoxycarbonylamino)-7-oxo-7-(...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay in presence of DTT | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314124 ((S,E)-ethyl 4-(tert-butoxycarbonylamino)-7-oxo-7-(...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314132 ((2S,5S,8S,11S,E)-1-Benzyl 16-ethyl 11-(3-amino-3-o...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine protease (Trypanosoma brucei rhodesiense) | BDBM50314129 ((S,E)-3-((S)-1-Benzyloxycarbonyl-2-phenylethylcarb...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay | J Med Chem 53: 1951-63 (2010) Article DOI: 10.1021/jm900946n BindingDB Entry DOI: 10.7270/Q2V9887Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50318714 ((2S,15S,18S,21S,24S)-15-(acetamidomethyl)-2-benzyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of human liver cathepsin B | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Bos taurus (bovine)) | BDBM50318718 ((2S,15S,18S,21S,24S)-15-(acetamidomethyl)-2-benzyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of bovine spleen cathepsin L | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50318711 ((2S,15S,18S,21S,24S)-15-(2-amino-2-oxoethyl)-2-ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of human liver cathepsin B | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50318710 ((2S,15S,18S,21S,24S)-2,15-dibenzyl-24-carbamoyl-18...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of human liver cathepsin B | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Bos taurus (bovine)) | BDBM50318715 ((2S,15S,18S,21S,24S)-2-benzyl-24-carbamoyl-18,21-d...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of bovine spleen cathepsin L | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Bos taurus (bovine)) | BDBM50318716 ((2S,8S,15S,18S,21S,24S)-2-benzyl-24-carbamoyl-18,2...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of bovine spleen cathepsin L | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Bos taurus (bovine)) | BDBM50318710 ((2S,15S,18S,21S,24S)-2,15-dibenzyl-24-carbamoyl-18...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of bovine spleen cathepsin L | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Bos taurus (bovine)) | BDBM50318712 ((2S,15S,18S,21S,24S)-15-(2-amino-2-oxoethyl)-2-ben...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of bovine spleen cathepsin L | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Bos taurus (bovine)) | BDBM50318717 ((2S,15S,18S,21S,24S)-15-(acetamidomethyl)-2-benzyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Duisburg-Essen Curated by ChEMBL | Assay Description Inhibition of bovine spleen cathepsin L | J Med Chem 52: 5662-72 (2009) Article DOI: 10.1021/jm900629w BindingDB Entry DOI: 10.7270/Q298876S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A/B chain (Human-Homo sapiens (Human)) | BDBM577483 (US11472838, Compound 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The most relevant off-targets are the transglutaminase isoenzymes especially tissue transglutaminase (TG2) because the enzyme is ubiquitously express... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII B chain (Rabbit) | BDBM577483 (US11472838, Compound 5) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The most relevant off-targets are the transglutaminase isoenzymes especially tissue transglutaminase (TG2) because the enzyme is ubiquitously express... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Rat) | BDBM577483 (US11472838, Compound 5) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577537 (US11472838, Compound Ref. 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A/B chain (Human-Homo sapiens (Human)) | BDBM577483 (US11472838, Compound 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577509 (US11472838, Compound 27 | US11472838, Compound 31a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577546 (US11472838, Compound Ref. 21) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM50245478 (CHEMBL4081588 | US11472838, Compound Ref. 25) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577540 (US11472838, Compound Ref. 16) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577484 (US11472838, Compound 1a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577511 (US11472838, Compound 29 | US11472838, Compound 32a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-glutamine gamma-glutamyltransferase 2 (Homo sapiens (Human)) | BDBM577488 (US11472838, Compound 6) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577487 (US11472838, Compound 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-glutamine gamma-glutamyltransferase 2 (Homo sapiens (Human)) | BDBM577487 (US11472838, Compound 4) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577512 (US11472838, Compound 30) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Crab-eating macaque) | BDBM577483 (US11472838, Compound 5) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Mouse) | BDBM577483 (US11472838, Compound 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The most relevant off-targets are the transglutaminase isoenzymes especially tissue transglutaminase (TG2) because the enzyme is ubiquitously express... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair |
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