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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] | ||
| Ligand | BDBM384330 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Biochemical Assay | ||
| IC50 | <30±n/a nM | ||
| Citation |  de Vicente Fidalgo, J; Estrada, AA; Feng, JA; Lyssikatos, JP; Sweeney, ZK Compounds, compositions, and methods US Patent US11591316 Publication Date 2/28/2023 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] | |||
| Name: | Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] | ||
| Synonyms: | LRRK2 | LRRK2 G2019S | LRRK2_HUMAN | Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (G2019S) | Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)(G2019S) | Leucine-rich repeat serine/threonine-protein kinase 2 G2019S | PARK8 | ||
| Type: | n/a | ||
| Mol. Mass.: | 286143.23 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q5S007(G2019S) | ||
| Residue: | 2527 | ||
| Sequence: |
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| BDBM384330 | |||
| n/a | |||
| Name | BDBM384330 | ||
| Synonyms: | US10590114, No. 27 | US11111235, No. 27 | US11591316, Compound 27 | US9932325, Example 26 | US9932325, Example 27 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H18F3N7 | ||
| Mol. Mass. | 365.3562 | ||
| SMILES | CCNc1nc(Nc2cnn(C3C[C@@H](C3)C#N)c2C)ncc1C(F)(F)F |r,wU:13.15,(5.42,.28,;4.09,1.05,;4.09,2.59,;2.75,3.36,;1.42,2.59,;.08,3.36,;-1.25,2.59,;-1.25,1.05,;-0,.14,;-.48,-1.32,;-2.02,-1.32,;-2.79,-2.65,;-4.28,-3.05,;-3.88,-4.54,;-2.39,-4.14,;-4.65,-5.87,;-5.42,-7.21,;-2.5,.14,;-3.98,.54,;.08,4.9,;1.42,5.67,;2.75,4.9,;4.09,5.67,;5.42,4.9,;4.09,7.21,;5.42,6.44,)| | ||
| Structure | 
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