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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] | ||
| Ligand | BDBM384350 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Biochemical Assay | ||
| IC50 | <30±n/a nM | ||
| Citation |  de Vicente Fidalgo, J; Estrada, AA; Feng, JA; Lyssikatos, JP; Sweeney, ZK Compounds, compositions, and methods US Patent US11591316 Publication Date 2/28/2023 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] | |||
| Name: | Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] | ||
| Synonyms: | LRRK2 | LRRK2 G2019S | LRRK2_HUMAN | Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (G2019S) | Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)(G2019S) | Leucine-rich repeat serine/threonine-protein kinase 2 G2019S | PARK8 | ||
| Type: | n/a | ||
| Mol. Mass.: | 286143.23 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q5S007(G2019S) | ||
| Residue: | 2527 | ||
| Sequence: |
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| BDBM384350 | |||
| n/a | |||
| Name | BDBM384350 | ||
| Synonyms: | US10590114, No. 35B | US11111235, No. 35B | US11591316, Compound 35B | US9932325, Example 35B | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H18F3N7 | ||
| Mol. Mass. | 365.3562 | ||
| SMILES | CCNc1nc(Nc2cn(nc2C)[C@@H]2C[C@@H](C2)C#N)ncc1C(F)(F)F |r,wD:13.13,15.18,(4.7,.38,;3.37,1.15,;3.37,2.69,;2.03,3.46,;.7,2.69,;-.63,3.46,;-1.97,2.69,;-1.97,1.15,;-.72,.25,;-1.2,-1.22,;-2.74,-1.22,;-3.21,.25,;-4.7,.65,;-.43,-2.55,;1.06,-2.95,;.67,-4.46,;-.83,-4.04,;1.44,-5.79,;2.21,-7.13,;-.63,5,;.7,5.77,;2.08,5.03,;3.42,5.8,;4.75,6.57,;2.65,7.13,;4.19,4.47,)| | ||
| Structure | 
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