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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A2a | ||
| Ligand | BDBM605707 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | A2A Tag-lite HTRF Assay | ||
| Ki | <10±n/a nM | ||
| Citation |  Wang, X; Gan, P; Huang, T; Qi, C; Qian, D; Wu, L; Yao, W; Yu, Z; Zhang, F; Zhao, L; He, C Imidazopyrimidines and triazolopyrimidines as A2A / A2B inhibitors US Patent US11673894 Publication Date 6/13/2023 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A2a | |||
| Name: | Adenosine receptor A2a | ||
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44716.46 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P29274 | ||
| Residue: | 412 | ||
| Sequence: |
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| BDBM605707 | |||
| n/a | |||
| Name | BDBM605707 | ||
| Synonyms: | US11673894, Ex. No. 85 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H17FN8O2 | ||
| Mol. Mass. | 456.4319 | ||
| SMILES | Cc1nc(CO)c(o1)-c1c(nc(N)n2nc(Cc3ncccc3F)nc12)-c1cccc(c1)C#N |(-1.7,4.93,;-.93,3.6,;.61,3.6,;1.09,2.13,;2.57,1.73,;3.66,2.82,;-.16,1.23,;-1.41,2.13,;-.16,-.31,;-1.49,-1.08,;-1.49,-2.62,;-.16,-3.39,;-.16,-4.93,;1.17,-2.62,;2.64,-3.1,;3.54,-1.85,;5.08,-1.85,;5.85,-.52,;5.08,.82,;5.85,2.15,;7.39,2.15,;8.16,.82,;7.39,-.52,;8.16,-1.85,;2.64,-.61,;1.17,-1.08,;-2.83,-.31,;-2.83,1.23,;-4.16,2,;-5.5,1.23,;-5.5,-.31,;-4.16,-1.08,;-6.83,-1.08,;-8.16,-1.85,)| | ||
| Structure | 
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