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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A2a | ||
| Ligand | BDBM605713 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | A2A Tag-lite HTRF Assay | ||
| Ki | <10±n/a nM | ||
| Citation |  Wang, X; Gan, P; Huang, T; Qi, C; Qian, D; Wu, L; Yao, W; Yu, Z; Zhang, F; Zhao, L; He, C Imidazopyrimidines and triazolopyrimidines as A2A / A2B inhibitors US Patent US11673894 Publication Date 6/13/2023 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A2a | |||
| Name: | Adenosine receptor A2a | ||
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44716.46 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P29274 | ||
| Residue: | 412 | ||
| Sequence: |
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| BDBM605713 | |||
| n/a | |||
| Name | BDBM605713 | ||
| Synonyms: | US11673894, Ex. No. 91 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H18N8O2 | ||
| Mol. Mass. | 438.4414 | ||
| SMILES | Cc1ncoc1-c1c(nc(N)n2nc(Cc3ncccc3CO)nc12)-c1cccc(c1)C#N |(1.8,2.86,;.32,3.26,;-.16,4.73,;-1.7,4.73,;-2.18,3.26,;-.93,2.36,;-.93,.82,;-2.26,.05,;-2.26,-1.49,;-.93,-2.26,;-.93,-3.8,;.4,-1.49,;1.87,-1.97,;2.77,-.72,;4.31,-.72,;5.08,-2.06,;4.31,-3.39,;5.08,-4.73,;6.62,-4.73,;7.39,-3.39,;6.62,-2.06,;7.39,-.72,;8.93,-.72,;1.87,.52,;.4,.05,;-3.6,.82,;-3.6,2.36,;-4.93,3.13,;-6.27,2.36,;-6.31,.79,;-4.93,.05,;-7.65,.02,;-8.98,-.75,)| | ||
| Structure | 
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