| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein spinster homolog 1 |
|---|
| Ligand | BDBM627463 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | S1P Transporter Assay |
|---|
| IC50 | <2000±n/a nM |
|---|
| Citation |  Lynch, KR; Kharel, Y; Santos, WL; Fritzemeier, RG; Burgio, AL; Shrader, C; Foster, D INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY US Patent US20230331683 Publication Date 10/19/2023 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein spinster homolog 1 |
|---|
| Name: | Protein spinster homolog 1 |
|---|
| Synonyms: | HSpin1 | SPNS1 | Spinster-like protein 1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 56629.53 |
|---|
| Organism: | Human |
|---|
| Description: | Q9H2V7 |
|---|
| Residue: | 528 |
|---|
| Sequence: | MAGSDTAPFLSQADDPDDGPVPGTPGLPGSTGNPKSEEPEVPDQEGLQRITGLSPGRSAL
IVAVLCYINLLNYMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFGYLGD
RYNRKYLMCGGIAFWSLVTLGSSFIPGEHFWLLLLTRGLVGVGEASYSTIAPTLIADLFV
ADQRSRMLSIFYFAIPVGSGLGYIAGSKVKDMAGDWHWALRVTPGLGVVAVLLLFLVVRE
PPRGAVERHSDLPPLNPTSWWADLRALARNPSFVLSSLGFTAVAFVTGSLALWAPAFLLR
SRVVLGETPPCLPGDSCSSSDSLIFGLITCLTGVLGVGLGVEISRRLRHSNPRADPLVCA
TGLLGSAPFLFLSLACARGSIVATYIFIFIGETLLSMNWAIVADILLYVVIPTRRSTAEA
FQIVLSHLLGDAGSPYLIGLISDRLRRNWPPSFLSEFRALQFSLMLCAFVGALGGAAFLG
TAIFIEADRRRAQLHVQGLLHEAGSTDDRIVVPQRGRSTRVPVASVLI
|
|
|
|---|
| BDBM627463 |
|---|
| n/a |
|---|
| Name | BDBM627463 |
|---|
| Synonyms: | US20230331683, Compound 13l |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H32FN3O |
|---|
| Mol. Mass. | 361.4967 |
|---|
| SMILES | CCCCCCCCCCc1ccc2oc(N[C@@H]3CNC[C@@H]3F)nc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
