Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50562760 (CHEMBL4750447) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50562761 (CHEMBL4782021) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50562759 (CHEMBL4783605) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50562758 (CHEMBL4755938) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM50343725 ((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of JAK2 V617F mutant (unknown origin) using L-Ahx-IPTSPITTTYFFFKKK-COOH as substrate in presence of ATP | Bioorg Med Chem 24: 4647-4651 (2016) Article DOI: 10.1016/j.bmc.2016.07.069 BindingDB Entry DOI: 10.7270/Q2D79FW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50562757 (CHEMBL3814580) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.980 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50177006 (CHEMBL3814849) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50041978 (CHEMBL3134157) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu... | J Med Chem 58: 1879-99 (2015) Article DOI: 10.1021/jm501760d BindingDB Entry DOI: 10.7270/Q2PK0HV3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50041978 (CHEMBL3134157) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human SphK1 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]SIP production using D-erythro-sphingo... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115941 BindingDB Entry DOI: 10.7270/Q23B63ST | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sphingosine kinase 1 (Mus musculus) | BDBM50041978 (CHEMBL3134157) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of SphK1 in mouse erythrocytes using sphingosine as substrate by luminescence assay | ACS Med Chem Lett 7: 229-34 (2016) Article DOI: 10.1021/acsmedchemlett.5b00304 BindingDB Entry DOI: 10.7270/Q22B90ZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50041978 (CHEMBL3134157) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive-inhibition of recombinant human C-terminal His6-tagged Sphk1 expressed in baculovirus infected Sf21 insect cells using varying levels of ... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50041978 (CHEMBL3134157) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human C-terminal His-tagged SPHK1 expressed in fall armyworm sf21 cells using sphingosine as substrate after 1 hr by FITC-b... | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50562757 (CHEMBL3814580) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50562759 (CHEMBL4783605) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50562758 (CHEMBL4755938) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50562761 (CHEMBL4782021) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50562760 (CHEMBL4750447) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50177006 (CHEMBL3814849) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.113121 BindingDB Entry DOI: 10.7270/Q2F193FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50077147 (CHEMBL3416846) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu... | J Med Chem 58: 1879-99 (2015) Article DOI: 10.1021/jm501760d BindingDB Entry DOI: 10.7270/Q2PK0HV3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50077147 (CHEMBL3416846) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human SphK1 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]SIP production using D-erythro-sphingo... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115941 BindingDB Entry DOI: 10.7270/Q23B63ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50514473 (CHEMBL4453931) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ... | J Med Chem 63: 1178-1198 (2020) Article DOI: 10.1021/acs.jmedchem.9b01508 BindingDB Entry DOI: 10.7270/Q2WH2T9K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50514473 (CHEMBL4453931) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human SphK2 assessed as decrease in [33P]SIP production using sphingosine as substrate in presence of [gamma33P]-ATP by sci... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115941 BindingDB Entry DOI: 10.7270/Q23B63ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50266426 (CHEMBL4076808) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation counting | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50266429 (CHEMBL4074731) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation counting | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM174126 (US9688668, 1a) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Patent Foundation US Patent | Assay Description SLR080811, prepared as the HCl salt, was tested first at recombinant SphK1 and SphK2 using a broken cell assay. | US Patent US9688668 (2017) BindingDB Entry DOI: 10.7270/Q29K48C1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50266426 (CHEMBL4076808) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK1 using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation counting | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50343829 ((S)-1-(4-Dodecylbenzoyl)pyrrolidine-2-carboximidam...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu... | J Med Chem 58: 1879-99 (2015) Article DOI: 10.1021/jm501760d BindingDB Entry DOI: 10.7270/Q2PK0HV3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50266428 (CHEMBL4082275) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation counting | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50266427 (CHEMBL4071762) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation counting | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50514475 (CHEMBL4456325) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 186 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ... | J Med Chem 63: 1178-1198 (2020) Article DOI: 10.1021/acs.jmedchem.9b01508 BindingDB Entry DOI: 10.7270/Q2WH2T9K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50514477 (CHEMBL4593983) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 192 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ... | J Med Chem 63: 1178-1198 (2020) Article DOI: 10.1021/acs.jmedchem.9b01508 BindingDB Entry DOI: 10.7270/Q2WH2T9K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50514478 (CHEMBL4570134) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 197 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ... | J Med Chem 63: 1178-1198 (2020) Article DOI: 10.1021/acs.jmedchem.9b01508 BindingDB Entry DOI: 10.7270/Q2WH2T9K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50514474 (CHEMBL4462152) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 201 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ... | J Med Chem 63: 1178-1198 (2020) Article DOI: 10.1021/acs.jmedchem.9b01508 BindingDB Entry DOI: 10.7270/Q2WH2T9K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50266436 (CHEMBL4093841) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation counting | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50266447 (CHEMBL4062916) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK1 using sphingosine as substrate by ADP-Quest assay | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50514480 (CHEMBL4466524) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of recombinant human SphK2 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]S1P production using varying level of ... | J Med Chem 63: 1178-1198 (2020) Article DOI: 10.1021/acs.jmedchem.9b01508 BindingDB Entry DOI: 10.7270/Q2WH2T9K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50266425 (CHEMBL4076479) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation counting | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Mus musculus (Mouse)) | BDBM50514480 (CHEMBL4466524) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of recombinant mouse SphK2 expressed in baculovirus infected Sf9 insect cells using D-erythro-sphingosine as substrate measured after 30 m... | J Med Chem 63: 1178-1198 (2020) Article DOI: 10.1021/acs.jmedchem.9b01508 BindingDB Entry DOI: 10.7270/Q2WH2T9K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Mus musculus) | BDBM50266437 (CHEMBL4092871) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant mouse SPHK1 using sphingosine as substrate in presence ATP | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50552501 (CHEMBL4799862) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human SphK2 assessed as decrease in [33P]SIP production using sphingosine as substrate in presence of [gamma33P]-ATP by sci... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115941 BindingDB Entry DOI: 10.7270/Q23B63ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50552497 (CHEMBL4763909) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 679 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human SphK1 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]SIP production using D-erythro-sphingo... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115941 BindingDB Entry DOI: 10.7270/Q23B63ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50266427 (CHEMBL4071762) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK1 using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation counting | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50266446 (CHEMBL4074878) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 730 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK1 using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation counting | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50177007 (CHEMBL3814505) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 730 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of human recombinant SphK1 using sphingosine as substrate incubated for 20 mins by scintillation counting analysis in presence of [gamma-3... | ACS Med Chem Lett 7: 229-34 (2016) Article DOI: 10.1021/acsmedchemlett.5b00304 BindingDB Entry DOI: 10.7270/Q22B90ZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50266428 (CHEMBL4082275) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK1 using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation counting | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50266425 (CHEMBL4076479) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK1 using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation counting | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50266446 (CHEMBL4074878) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of recombinant human SPHK2 at using sphingosine as substrate after 30 mins in presence of gamma-[32P]-ATP by liquid scintillation counting | J Med Chem 60: 3933-3957 (2017) Article DOI: 10.1021/acs.jmedchem.7b00233 BindingDB Entry DOI: 10.7270/Q2DJ5J3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50177007 (CHEMBL3814505) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of human recombinant SphK2 using sphingosine as substrate incubated for 20 mins by scintillation counting analysis in presence of [gamma-3... | ACS Med Chem Lett 7: 229-34 (2016) Article DOI: 10.1021/acsmedchemlett.5b00304 BindingDB Entry DOI: 10.7270/Q22B90ZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50177008 (CHEMBL3814234) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 930 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of human recombinant SphK1 using sphingosine as substrate incubated for 20 mins by scintillation counting analysis in presence of [gamma-3... | ACS Med Chem Lett 7: 229-34 (2016) Article DOI: 10.1021/acsmedchemlett.5b00304 BindingDB Entry DOI: 10.7270/Q22B90ZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50552497 (CHEMBL4763909) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 951 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human SphK2 assessed as decrease in [33P]SIP production using sphingosine as substrate in presence of [gamma33P]-ATP by sci... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115941 BindingDB Entry DOI: 10.7270/Q23B63ST | |||||||||||
More data for this Ligand-Target Pair |
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