| Reaction Details |
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 | Report a problem with these data |
| Target | Protein spinster homolog 1 |
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| Ligand | BDBM627465 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | S1P Transporter Assay |
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| IC50 | >2000±n/a nM |
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| Citation |  Lynch, KR; Kharel, Y; Santos, WL; Fritzemeier, RG; Burgio, AL; Shrader, C; Foster, D INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY US Patent US20230331683 Publication Date 10/19/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein spinster homolog 1 |
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| Name: | Protein spinster homolog 1 |
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| Synonyms: | HSpin1 | SPNS1 | Spinster-like protein 1 |
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| Type: | Protein |
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| Mol. Mass.: | 56629.53 |
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| Organism: | Human |
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| Description: | Q9H2V7 |
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| Residue: | 528 |
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| Sequence: | MAGSDTAPFLSQADDPDDGPVPGTPGLPGSTGNPKSEEPEVPDQEGLQRITGLSPGRSAL
IVAVLCYINLLNYMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFGYLGD
RYNRKYLMCGGIAFWSLVTLGSSFIPGEHFWLLLLTRGLVGVGEASYSTIAPTLIADLFV
ADQRSRMLSIFYFAIPVGSGLGYIAGSKVKDMAGDWHWALRVTPGLGVVAVLLLFLVVRE
PPRGAVERHSDLPPLNPTSWWADLRALARNPSFVLSSLGFTAVAFVTGSLALWAPAFLLR
SRVVLGETPPCLPGDSCSSSDSLIFGLITCLTGVLGVGLGVEISRRLRHSNPRADPLVCA
TGLLGSAPFLFLSLACARGSIVATYIFIFIGETLLSMNWAIVADILLYVVIPTRRSTAEA
FQIVLSHLLGDAGSPYLIGLISDRLRRNWPPSFLSEFRALQFSLMLCAFVGALGGAAFLG
TAIFIEADRRRAQLHVQGLLHEAGSTDDRIVVPQRGRSTRVPVASVLI
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| BDBM627465 |
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| n/a |
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| Name | BDBM627465 |
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| Synonyms: | US20230331683, Compound 13n |
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| Type | Small organic molecule |
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| Emp. Form. | C21H33N3O |
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| Mol. Mass. | 343.5062 |
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| SMILES | CCCCCCCCCCc1ccc2oc(nc2c1)N1CC[C@H](N)C1 |
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| Structure | 
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