Reaction Details | |||
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Target | Alpha-1-antitrypsin | ||
Ligand | BDBM629192 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Biochemical Assay (Z-AAT Elastase Activity Assay) | ||
IC50 | >5000±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Alpha-1-antitrypsin | |||
Name: | Alpha-1-antitrypsin | ||
Synonyms: | Alpha-1 protease inhibitor | Alpha-1-antiproteinase | Serpin A1 | ||
Type: | Protein | ||
Mol. Mass.: | 46727.42 | ||
Organism: | Human | ||
Description: | P01009 | ||
Residue: | 418 | ||
Sequence: |
| ||
BDBM629192 | |||
n/a | |||
Name | BDBM629192 | ||
Synonyms: | US20230339915, Compound 60 | ||
Type | Small organic molecule | ||
Emp. Form. | C24H23F4NO3 | ||
Mol. Mass. | 449.4379 | ||
SMILES | CC(C)c1c([C@H]2C[C@@](C2)(C(O)=O)C(F)(F)F)c2cc(O)ccc2n1-c1ccc(F)c(C)c1 |r,wU:7.9,wD:5.4,7.12,(-1.83,2.6,;-1.06,1.27,;-1.83,-.06,;.48,1.27,;1.39,.02,;.91,-1.44,;-.46,-2.14,;.24,-3.51,;1.61,-2.81,;.94,-4.88,;2.47,-4.96,;.1,-6.17,;-1.14,-4.21,;-2.51,-4.91,;-1.83,-2.84,;-.44,-5.58,;2.85,.5,;4.18,-.27,;5.52,.5,;6.85,-.27,;5.52,2.04,;4.18,2.81,;2.85,2.04,;1.39,2.52,;.91,3.98,;1.94,5.13,;1.46,6.59,;-.04,6.91,;-.52,8.37,;-1.07,5.77,;-2.58,6.09,;-.6,4.3,)| | ||
Structure | ![]() |