Reaction Details | |||
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Target | Alpha-1-antitrypsin | ||
Ligand | BDBM629199 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Biochemical Assay (Z-AAT Elastase Activity Assay) | ||
IC50 | >5000±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Alpha-1-antitrypsin | |||
Name: | Alpha-1-antitrypsin | ||
Synonyms: | Alpha-1 protease inhibitor | Alpha-1-antiproteinase | Serpin A1 | ||
Type: | Protein | ||
Mol. Mass.: | 46727.42 | ||
Organism: | Human | ||
Description: | P01009 | ||
Residue: | 418 | ||
Sequence: |
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BDBM629199 | |||
n/a | |||
Name | BDBM629199 | ||
Synonyms: | US20230339915, Compound 77 | ||
Type | Small organic molecule | ||
Emp. Form. | C22H21ClFNO3 | ||
Mol. Mass. | 401.858 | ||
SMILES | CC(C)c1c([C@H]2C[C@@H](C2)C(O)=O)c2cc(O)ccc2n1-c1ccc(F)c(Cl)c1 |r,wU:5.4,wD:7.9,(3.99,1.15,;3.19,-.17,;3.95,-1.51,;1.65,-.18,;.75,1.07,;1.24,2.53,;.47,3.86,;1.81,4.63,;2.58,3.3,;2.29,6.09,;3.8,6.42,;1.27,7.25,;-.72,.59,;-2.05,1.36,;-3.38,.59,;-4.74,1.32,;-3.38,-.95,;-2.05,-1.72,;-.72,-.95,;.75,-1.42,;1.25,-2.88,;.25,-4.04,;.76,-5.5,;2.27,-5.78,;2.76,-7.25,;3.27,-4.62,;4.74,-4.97,;2.77,-3.16,)| | ||
Structure | ![]() |