Reaction Details | |||
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Target | Alpha-1-antitrypsin | ||
Ligand | BDBM629203 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Biochemical Assay (Z-AAT Elastase Activity Assay) | ||
IC50 | 3500±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Alpha-1-antitrypsin | |||
Name: | Alpha-1-antitrypsin | ||
Synonyms: | Alpha-1 protease inhibitor | Alpha-1-antiproteinase | Serpin A1 | ||
Type: | Protein | ||
Mol. Mass.: | 46727.42 | ||
Organism: | Human | ||
Description: | P01009 | ||
Residue: | 418 | ||
Sequence: |
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BDBM629203 | |||
n/a | |||
Name | BDBM629203 | ||
Synonyms: | US20230339915, Compound 89 | ||
Type | Small organic molecule | ||
Emp. Form. | C23H23F2NO3 | ||
Mol. Mass. | 399.4304 | ||
SMILES | CC(C)c1c([C@H]2C[C@@H](C2)C(O)=O)c2c(F)c(O)ccc2n1-c1ccc(F)c(C)c1 |r,wU:5.4,wD:7.9,(3.96,1.17,;3.19,-.17,;3.96,-1.5,;1.65,-.17,;.74,1.08,;1.21,2.55,;.44,3.88,;1.78,4.65,;2.55,3.32,;2.22,6.12,;3.72,6.47,;1.17,7.25,;-.72,.6,;-2.06,1.37,;-2.06,2.91,;-3.39,.6,;-4.74,1.34,;-3.39,-.94,;-2.06,-1.71,;-.72,-.94,;.74,-1.41,;1.25,-2.87,;.23,-4.02,;.72,-5.48,;2.23,-5.78,;2.71,-7.25,;3.25,-4.63,;4.74,-5,;2.76,-3.17,)| | ||
Structure | ![]() |