Reaction Details | |||
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Target | Alpha-1-antitrypsin | ||
Ligand | BDBM629207 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Biochemical Assay (Z-AAT Elastase Activity Assay) | ||
IC50 | 3500±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Alpha-1-antitrypsin | |||
Name: | Alpha-1-antitrypsin | ||
Synonyms: | Alpha-1 protease inhibitor | Alpha-1-antiproteinase | Serpin A1 | ||
Type: | Protein | ||
Mol. Mass.: | 46727.42 | ||
Organism: | Human | ||
Description: | P01009 | ||
Residue: | 418 | ||
Sequence: |
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BDBM629207 | |||
n/a | |||
Name | BDBM629207 | ||
Synonyms: | US20230339915, Compound 97 | ||
Type | Small organic molecule | ||
Emp. Form. | C26H28FNO3 | ||
Mol. Mass. | 421.5038 | ||
SMILES | CC(C)c1c(C2CC3(CC(C3)C(O)=O)C2)c2cc(O)ccc2n1-c1ccc(F)c(C)c1 |w:9.11,(3.97,.13,;3.17,-1.18,;3.92,-2.53,;1.63,-1.19,;.73,.05,;1.2,1.52,;2.58,2.22,;1.88,3.59,;3.25,4.29,;2.55,5.66,;1.18,4.96,;3.03,7.12,;4.53,7.44,;1.99,8.27,;.5,2.89,;-.74,-.42,;-2.07,.35,;-3.4,-.42,;-4.75,.32,;-3.4,-1.96,;-2.07,-2.73,;-.74,-1.96,;.73,-2.44,;1.21,-3.9,;.21,-5.07,;.72,-6.52,;2.24,-6.81,;2.72,-8.27,;3.24,-5.64,;4.75,-5.92,;2.73,-4.18,)| | ||
Structure | ![]() |