Reaction Details | |||
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Target | Alpha-1-antitrypsin | ||
Ligand | BDBM629210 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Biochemical Assay (Z-AAT Elastase Activity Assay) | ||
IC50 | >5000±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Alpha-1-antitrypsin | |||
Name: | Alpha-1-antitrypsin | ||
Synonyms: | Alpha-1 protease inhibitor | Alpha-1-antiproteinase | Serpin A1 | ||
Type: | Protein | ||
Mol. Mass.: | 46727.42 | ||
Organism: | Human | ||
Description: | P01009 | ||
Residue: | 418 | ||
Sequence: |
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BDBM629210 | |||
n/a | |||
Name | BDBM629210 | ||
Synonyms: | US20230339915, Compound 108 | ||
Type | Small organic molecule | ||
Emp. Form. | C26H27F2NO4 | ||
Mol. Mass. | 455.4937 | ||
SMILES | Cc1cc(ccc1F)-n1c(C2CCOCC2)c([C@H]2C[C@@](CF)(C2)C(O)=O)c2cc(O)ccc12 |r,wU:19.21,17.18,wD:19.25,(4.01,-4.74,;2.51,-4.43,;2,-2.98,;.48,-2.69,;-.52,-3.86,;-.01,-5.31,;1.5,-5.6,;1.98,-7.06,;-.02,-1.23,;.89,.01,;2.43,0,;3.2,1.34,;4.74,1.34,;5.51,0,;4.74,-1.33,;3.2,-1.33,;-.02,1.26,;.47,2.72,;-.3,4.05,;1.03,4.82,;.3,6.18,;-1.24,6.18,;1.8,3.49,;2.4,5.52,;3.7,4.68,;2.41,7.06,;-1.48,.78,;-2.82,1.55,;-4.15,.78,;-5.51,1.51,;-4.15,-.76,;-2.82,-1.53,;-1.48,-.76,)| | ||
Structure | ![]() |