Reaction Details | |||
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Target | Alpha-1-antitrypsin | ||
Ligand | BDBM629225 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Biochemical Assay (Z-AAT Elastase Activity Assay) | ||
IC50 | <2000±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Alpha-1-antitrypsin | |||
Name: | Alpha-1-antitrypsin | ||
Synonyms: | Alpha-1 protease inhibitor | Alpha-1-antiproteinase | Serpin A1 | ||
Type: | Protein | ||
Mol. Mass.: | 46727.42 | ||
Organism: | Human | ||
Description: | P01009 | ||
Residue: | 418 | ||
Sequence: |
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BDBM629225 | |||
n/a | |||
Name | BDBM629225 | ||
Synonyms: | US20230339915, Compound 170 | ||
Type | Small organic molecule | ||
Emp. Form. | C26H24FNO3 | ||
Mol. Mass. | 417.4721 | ||
SMILES | CC(C)c1c(-c2ccc(cc2C)C(O)=O)c2cc(O)ccc2n1-c1ccc(F)c(C)c1 |(3.98,.74,;3.18,-.58,;3.93,-1.92,;1.64,-.58,;.74,.66,;1.22,2.12,;2.74,2.41,;3.24,3.87,;2.23,5.03,;.72,4.74,;.22,3.29,;-1.29,2.95,;2.76,6.48,;4.28,6.75,;1.77,7.66,;-.73,.19,;-2.06,.96,;-3.39,.19,;-4.75,.92,;-3.39,-1.35,;-2.06,-2.12,;-.73,-1.35,;.74,-1.83,;1.25,-3.28,;.23,-4.44,;.73,-5.9,;2.24,-6.2,;2.73,-7.66,;3.25,-5.04,;4.75,-5.42,;2.76,-3.58,)| | ||
Structure | ![]() |