Reaction Details | |||
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Target | Alpha-1-antitrypsin | ||
Ligand | BDBM629237 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Biochemical Assay (Z-AAT Elastase Activity Assay) | ||
IC50 | >5000±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Alpha-1-antitrypsin | |||
Name: | Alpha-1-antitrypsin | ||
Synonyms: | Alpha-1 protease inhibitor | Alpha-1-antiproteinase | Serpin A1 | ||
Type: | Protein | ||
Mol. Mass.: | 46727.42 | ||
Organism: | Human | ||
Description: | P01009 | ||
Residue: | 418 | ||
Sequence: |
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BDBM629237 | |||
n/a | |||
Name | BDBM629237 | ||
Synonyms: | US20230339915, Compound 219 | ||
Type | Small organic molecule | ||
Emp. Form. | C24H27FN2O4S | ||
Mol. Mass. | 458.546 | ||
SMILES | CC(C)c1c([C@@H]2C[C@@H](C2)C(=O)NS(C)(=O)=O)c2cc(O)ccc2n1-c1ccc(F)c(C)c1 |r,wU:5.4,7.9,(3.68,.89,;2.56,-.17,;3.62,-1.29,;1.02,-.18,;.12,1.07,;.61,2.52,;1.95,3.29,;1.18,4.63,;-.16,3.86,;1.69,6.08,;.69,7.25,;3.17,6.51,;4.24,5.41,;5.36,6.47,;5.32,4.31,;3.47,4.08,;-1.35,.59,;-2.68,1.36,;-4.01,.59,;-5.36,1.34,;-4.01,-.95,;-2.68,-1.72,;-1.35,-.95,;.12,-1.43,;.61,-2.88,;-.39,-4.06,;.13,-5.51,;1.64,-5.79,;2.13,-7.25,;2.64,-4.62,;4.16,-4.91,;2.13,-3.16,)| | ||
Structure | ![]() |