| Reaction Details |
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 | Report a problem with these data |
| Target | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 |
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| Ligand | BDBM645959 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MALT1 Protease Assay 2 |
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| IC50 | 550±n/a nM |
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| Citation |  Feng, S; Lawrenz, M; Krilov, G; Placzek, A; Nie, Z; Trzoss, L; Trzoss, M; Tang, H; Lagiakos, HR CYCLIC COMPOUNDS AND METHODS OF USING SAME US Patent US20240018157 Publication Date 1/18/2024 |
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| More Info.: | Get all data from this article, Assay Method |
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| Mucosa-associated lymphoid tissue lymphoma translocation protein 1 |
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| Name: | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 |
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| Synonyms: | MALT lymphoma-associated translocation | MALT lymphoma-associated translocation (MALT1) | MALT1 | MALT1_HUMAN | MLT | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | Paracaspase |
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| Type: | Enzyme |
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| Mol. Mass.: | 92257.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9UDY8 |
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| Residue: | 824 |
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| Sequence: | MSLLGDPLQALPPSAAPTGPLLAPPAGATLNRLREPLLRRLSELLDQAPEGRGWRRLAEL
AGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQ
LLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV
HVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP
GSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQD
SKKVEIIIGRTDEAVECTEDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLK
APLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENF
GNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDAL
KVTANIVFGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCH
LTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFDCGVQI
QLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVS
KDLPKHCLYTRLSSLQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRG
LGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPADSCHCS
RTPDAFISSFAHHASCHFSRSNVPVETTDEIPFSFSDRLRISEK
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| BDBM645959 |
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| n/a |
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| Name | BDBM645959 |
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| Synonyms: | US20240018157, Example 161 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13F6N7O |
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| Mol. Mass. | 445.3218 |
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| SMILES | Cc1nnc(cc1NC(=O)N1C[C@](C)(c2c1cnc1cc(F)nn21)C(F)(F)F)C(F)F |r| |
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| Structure | 
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