| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
|---|
| Ligand | BDBM323597 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Luciferase Assay |
|---|
| EC50 | 694±n/a nM |
|---|
| Citation |  Downes, M; Evans, R; Kluge, A; Lagu, B; Miura, M; Panigrahi, SK; Patane, M; Samajdar, S; Senaiar, R; Takahashi, T PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof US Patent US10188627 Publication Date 1/29/2019 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Peroxisome proliferator-activated receptor delta |
|---|
| Name: | Peroxisome proliferator-activated receptor delta |
|---|
| Synonyms: | NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 49910.45 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q03181 |
|---|
| Residue: | 441 |
|---|
| Sequence: | MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY
|
|
|
|---|
| BDBM323597 |
|---|
| n/a |
|---|
| Name | BDBM323597 |
|---|
| Synonyms: | (E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phenoxy)-3-methylhex-2-enoic acid | US10188627, Compound 8i |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H27NO5 |
|---|
| Mol. Mass. | 433.4963 |
|---|
| SMILES | CN(Cc1ccccc1OCCC\C(C)=C\C(O)=O)C(=O)c1ccc(cc1)-c1ccco1 |
|---|
| Structure | 
|
|---|
Search and Browse
